WO2007016455A3 - Compositions and methods using aminoglycosides to bind dna and rna - Google Patents

Compositions and methods using aminoglycosides to bind dna and rna Download PDF

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Publication number
WO2007016455A3
WO2007016455A3 PCT/US2006/029675 US2006029675W WO2007016455A3 WO 2007016455 A3 WO2007016455 A3 WO 2007016455A3 US 2006029675 W US2006029675 W US 2006029675W WO 2007016455 A3 WO2007016455 A3 WO 2007016455A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
methods
aminoglycosides
rna
bind dna
Prior art date
Application number
PCT/US2006/029675
Other languages
French (fr)
Other versions
WO2007016455A2 (en
Inventor
Dev Priya Arya
Liang Xue
Bert Willis
Irudayasamy Charles
Original Assignee
Univ Clemson Res Foundation
Dev Priya Arya
Liang Xue
Bert Willis
Irudayasamy Charles
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Clemson Res Foundation, Dev Priya Arya, Liang Xue, Bert Willis, Irudayasamy Charles filed Critical Univ Clemson Res Foundation
Publication of WO2007016455A2 publication Critical patent/WO2007016455A2/en
Publication of WO2007016455A3 publication Critical patent/WO2007016455A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Disclosed are compositions and methods related to aminoglycoside dimers aminoglycoside conjugates, and their uses.
PCT/US2006/029675 2005-07-29 2006-07-31 Compositions and methods using aminoglycosides to bind dna and rna WO2007016455A2 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US70414605P 2005-07-29 2005-07-29
US70414705P 2005-07-29 2005-07-29
US70394705P 2005-07-29 2005-07-29
US60/704,147 2005-07-29
US60/704,146 2005-07-29
US60/703,947 2005-07-29
US70926305P 2005-08-18 2005-08-18
US60/709,263 2005-08-18

Publications (2)

Publication Number Publication Date
WO2007016455A2 WO2007016455A2 (en) 2007-02-08
WO2007016455A3 true WO2007016455A3 (en) 2007-12-13

Family

ID=37709260

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/029675 WO2007016455A2 (en) 2005-07-29 2006-07-31 Compositions and methods using aminoglycosides to bind dna and rna

Country Status (1)

Country Link
WO (1) WO2007016455A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9260476B2 (en) 2007-02-23 2016-02-16 The Research Foundation For The State University Of New York RNA targeting compounds and methods for making and using same
AU2008218939B2 (en) 2007-02-23 2014-05-08 The Research Foundation Of State University Of New York RNA targeting compounds and methods for making and using same
CN102256989B (en) * 2008-10-03 2016-01-06 聚糖生物科学有限责任公司 The anionic conjugates of glycosylated bacterial metabolite
WO2013016321A1 (en) 2011-07-26 2013-01-31 Elitech Holding B.V. Minor groove binder phosphoramidites and methods of use
US9410186B2 (en) 2012-07-11 2016-08-09 Nubad Llc Methods and compositions related to nucleic acid binding assays
CN113652432A (en) * 2021-08-20 2021-11-16 山东理工大学 Aminoglycoside antibiotic broad-spectrum aptamer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050085413A1 (en) * 2001-11-09 2005-04-21 Betty Jin Dimeric pharmaceutical compounds and their use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050085413A1 (en) * 2001-11-09 2005-04-21 Betty Jin Dimeric pharmaceutical compounds and their use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ARYA D.P.: "Reaching into the Major Groove of B-DNA: Synthesis and Nucleic Acid Binding of a Neomycin - Hoechst 33258 Conjugate", JACS COMMUNICATIONS, 19 September 2003 (2003-09-19), XP008091374, Retrieved from the Internet <URL:http://www.chemistry.clemson.edu/pdfs/Dev_3_neochoechst.pdf> *

Also Published As

Publication number Publication date
WO2007016455A2 (en) 2007-02-08

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