WO2007016377A3 - Dialysis solution including water-soluble polyelectrolyte osmotic agent - Google Patents
Dialysis solution including water-soluble polyelectrolyte osmotic agent Download PDFInfo
- Publication number
- WO2007016377A3 WO2007016377A3 PCT/US2006/029494 US2006029494W WO2007016377A3 WO 2007016377 A3 WO2007016377 A3 WO 2007016377A3 US 2006029494 W US2006029494 W US 2006029494W WO 2007016377 A3 WO2007016377 A3 WO 2007016377A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dialysis
- subject
- osmotic
- osmotic agents
- dialysis solution
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
Abstract
Dialysis solutions comprising aqueous solutions including physiologically acceptable salts and a polyelectrolyte osmotic agent are disclosed. The subject solutions provide an improved osmotic gradient resulting in reduced dialysis times and/or reduced volumes of required dialysis solution. Moreover, the subject osmotic agents do not significantly migrate into the patient's blood over the time period of dialysis nor are the subject osmotic agents as susceptible to forming detrimental degradation products during gamma sterilization. The subject osmotic agents are much less susceptible to microbial contamination than currently available osmotic agents used in dialysis. The use of free radical scavengers is also described along with the use of a filter to reduce the introduction of bacteria into the peritoneal cavity.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70348605P | 2005-07-28 | 2005-07-28 | |
US60/703,486 | 2005-07-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007016377A2 WO2007016377A2 (en) | 2007-02-08 |
WO2007016377A3 true WO2007016377A3 (en) | 2007-07-19 |
Family
ID=37709225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/029494 WO2007016377A2 (en) | 2005-07-28 | 2006-07-27 | Dialysis solution including water-soluble polyelectrolyte osmotic agent |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2007016377A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102012002372B4 (en) | 2012-02-08 | 2013-11-21 | Fresenius Medical Care Deutschland Gmbh | Concentrate for a dialysis fluid and dialysis fluid prepared therefrom |
WO2018215917A1 (en) * | 2017-05-24 | 2018-11-29 | Sequana Medical Ag | Direct sodium removal method, solution and apparatus to reduce fluid overload in heart failure patients |
CN115624566B (en) * | 2022-12-22 | 2023-03-10 | 广东省人民医院 | Peritoneal dialysis solution and preparation method and application thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020146386A1 (en) * | 2000-11-20 | 2002-10-10 | Jaime Simon | In vivo use of water absorbent polymers |
US20030202958A1 (en) * | 1999-10-15 | 2003-10-30 | Strickland Alan D. | Dialysis solution including polyglycol osmotic agent |
-
2006
- 2006-07-27 WO PCT/US2006/029494 patent/WO2007016377A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030202958A1 (en) * | 1999-10-15 | 2003-10-30 | Strickland Alan D. | Dialysis solution including polyglycol osmotic agent |
US20020146386A1 (en) * | 2000-11-20 | 2002-10-10 | Jaime Simon | In vivo use of water absorbent polymers |
Non-Patent Citations (3)
Title |
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TWARDOWSKI Z J ET AL: "COMPARISON OF GLUCOSE AND POLY ACRYLATE AS OSMOTIC AGENTS FOR PERITONEAL DIALYSIS IN-VITRO AND RAT STUDIES", CLINICAL RESEARCH, vol. 29, no. 5, 1981, & ANNUAL MEETING OF THE SOUTHERN SOCIETY FOR CLINICAL INVESTIGATION, NEW ORLEANS, LA., USA, JAN. 14-16, pages 874A, XP009081107, ISSN: 0009-9279 * |
TWARDOWSKI Z J ET AL: "LONG DWELL PERITONEAL DIALYSIS EXCHANGES IN RATS WITH POLY ACRYLATE AND GLUCOSE AS OSMOTIC AGENTS", CLINICAL RESEARCH, vol. 30, no. 1, 1982, & ANNUAL MEETING OF THE WESTERN SECTION OF THE AMERICAN FEDERATION FOR CLINICAL RESEARCH, CARMEL, CALI, pages 80A, XP009081106, ISSN: 0009-9279 * |
TWARDOWSKI Z J ET AL: "POLY ANIONS AND GLUCOSE AS OSMOTIC AGENTS IN SIMULATED PERITONEAL DIALYSIS", ARTIFICIAL ORGANS, vol. 7, no. 4, 1983, pages 420 - 427, XP009081105, ISSN: 0160-564X * |
Also Published As
Publication number | Publication date |
---|---|
WO2007016377A2 (en) | 2007-02-08 |
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