WO2007009711A3 - Octahydropentalene-substituted pyrazoline compounds, their preparation and use as medicaments - Google Patents

Octahydropentalene-substituted pyrazoline compounds, their preparation and use as medicaments Download PDF

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Publication number
WO2007009711A3
WO2007009711A3 PCT/EP2006/006985 EP2006006985W WO2007009711A3 WO 2007009711 A3 WO2007009711 A3 WO 2007009711A3 EP 2006006985 W EP2006006985 W EP 2006006985W WO 2007009711 A3 WO2007009711 A3 WO 2007009711A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
octahydropentalene
medicaments
pyrazoline compounds
substituted pyrazoline
Prior art date
Application number
PCT/EP2006/006985
Other languages
French (fr)
Other versions
WO2007009711A2 (en
Inventor
Jover Antonio Torrens
Minguez Susana Yenes
Original Assignee
Esteve Labor Dr
Jover Antonio Torrens
Minguez Susana Yenes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP05384018A external-priority patent/EP1743888A1/en
Priority claimed from EP06008579A external-priority patent/EP1849783A1/en
Application filed by Esteve Labor Dr, Jover Antonio Torrens, Minguez Susana Yenes filed Critical Esteve Labor Dr
Publication of WO2007009711A2 publication Critical patent/WO2007009711A2/en
Publication of WO2007009711A3 publication Critical patent/WO2007009711A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to octahydropentalene-substituted pyrazoline compounds, methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animals.
PCT/EP2006/006985 2005-07-15 2006-07-16 Octahydropentalene-substituted pyrazoline compounds, their preparation and use as medicaments WO2007009711A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP05384018A EP1743888A1 (en) 2005-07-15 2005-07-15 Carbonyl substituted pyrazoline compounds, their preparation and use as CB1 receptor modulators
US60/705,433 2005-07-15
EP05384018.7 2005-07-15
US70543305P 2005-08-05 2005-08-05
EP06008579A EP1849783A1 (en) 2006-04-26 2006-04-26 Octahydropentalene-substituted pyrazoline compounds, their preparation and use as medicaments
EP06008579.2 2006-04-26

Publications (2)

Publication Number Publication Date
WO2007009711A2 WO2007009711A2 (en) 2007-01-25
WO2007009711A3 true WO2007009711A3 (en) 2007-04-12

Family

ID=37622146

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/006985 WO2007009711A2 (en) 2005-07-15 2006-07-16 Octahydropentalene-substituted pyrazoline compounds, their preparation and use as medicaments

Country Status (2)

Country Link
ES (1) ES2327204B1 (en)
WO (1) WO2007009711A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005037199A2 (en) * 2003-10-10 2005-04-28 Bristol-Myers Squibb Company Pyrazole derivatives as cannabinoid receptor modulators
WO2005077911A1 (en) * 2004-02-17 2005-08-25 Laboratorios Del Dr. Esteve S.A. Substituted pyrazoline compounds, their preparation and use as medicaments
US20050261281A1 (en) * 2004-05-24 2005-11-24 Paolo Lazzari Pharmaceutical compounds
US20060030563A1 (en) * 1999-10-18 2006-02-09 Alexandros Makriyannis Novel pyrazole analogs acting on cannabinoid receptors

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060030563A1 (en) * 1999-10-18 2006-02-09 Alexandros Makriyannis Novel pyrazole analogs acting on cannabinoid receptors
WO2005037199A2 (en) * 2003-10-10 2005-04-28 Bristol-Myers Squibb Company Pyrazole derivatives as cannabinoid receptor modulators
WO2005077911A1 (en) * 2004-02-17 2005-08-25 Laboratorios Del Dr. Esteve S.A. Substituted pyrazoline compounds, their preparation and use as medicaments
US20050261281A1 (en) * 2004-05-24 2005-11-24 Paolo Lazzari Pharmaceutical compounds

Also Published As

Publication number Publication date
ES2327204B1 (en) 2010-06-07
WO2007009711A2 (en) 2007-01-25
ES2327204A1 (en) 2009-10-26

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