WO2007009541A8 - Medical test device and method for the optical determination of an analyte comprising means for compensating the ambient light background - Google Patents

Medical test device and method for the optical determination of an analyte comprising means for compensating the ambient light background

Info

Publication number
WO2007009541A8
WO2007009541A8 PCT/EP2006/005821 EP2006005821W WO2007009541A8 WO 2007009541 A8 WO2007009541 A8 WO 2007009541A8 EP 2006005821 W EP2006005821 W EP 2006005821W WO 2007009541 A8 WO2007009541 A8 WO 2007009541A8
Authority
WO
WIPO (PCT)
Prior art keywords
lightdetector
light
signal
test device
analyte
Prior art date
Application number
PCT/EP2006/005821
Other languages
French (fr)
Other versions
WO2007009541A1 (en
Inventor
Frederic Wehowski
Jean-Michel Asfour
Bernd Roesicke
Kai Hebestreit
Bernd Limburg
Original Assignee
Roche Diagnostics Gmbh
Hoffmann La Roche
Frederic Wehowski
Jean-Michel Asfour
Bernd Roesicke
Kai Hebestreit
Bernd Limburg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh, Hoffmann La Roche, Frederic Wehowski, Jean-Michel Asfour, Bernd Roesicke, Kai Hebestreit, Bernd Limburg filed Critical Roche Diagnostics Gmbh
Publication of WO2007009541A1 publication Critical patent/WO2007009541A1/en
Publication of WO2007009541A8 publication Critical patent/WO2007009541A8/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00—Photometry, e.g. photographic exposure meter
    • G01J1/02—Details
    • G01J1/04—Optical or mechanical part supplementary adjustable parts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00—Photometry, e.g. photographic exposure meter
    • G01J1/02—Details
    • G01J1/04—Optical or mechanical part supplementary adjustable parts
    • G01J1/0407—Optical elements not provided otherwise, e.g. manifolds, windows, holograms, gratings
    • G01J1/0425—Optical elements not provided otherwise, e.g. manifolds, windows, holograms, gratings using optical fibers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00—Photometry, e.g. photographic exposure meter
    • G01J1/10—Photometry, e.g. photographic exposure meter by comparison with reference light or electric value provisionally void
    • G01J1/16—Photometry, e.g. photographic exposure meter by comparison with reference light or electric value provisionally void using electric radiation detectors
    • G01J1/1626—Arrangements with two photodetectors, the signals of which are compared
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00—Photometry, e.g. photographic exposure meter
    • G01J1/42—Photometry, e.g. photographic exposure meter using electric radiation detectors
    • G01J1/4204—Photometry, e.g. photographic exposure meter using electric radiation detectors with determination of ambient light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00—Photometry, e.g. photographic exposure meter
    • G01J1/42—Photometry, e.g. photographic exposure meter using electric radiation detectors
    • G01J1/4228—Photometry, e.g. photographic exposure meter using electric radiation detectors arrangements with two or more detectors, e.g. for sensitivity compensation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00—Photometry, e.g. photographic exposure meter
    • G01J1/42—Photometry, e.g. photographic exposure meter using electric radiation detectors
    • G01J1/44—Electric circuits
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00—Photometry, e.g. photographic exposure meter
    • G01J1/02—Details
    • G01J1/0214—Constructional arrangements for removing stray light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00—Photometry, e.g. photographic exposure meter
    • G01J1/42—Photometry, e.g. photographic exposure meter using electric radiation detectors
    • G01J1/44—Electric circuits
    • G01J2001/444—Compensating; Calibrating, e.g. dark current, temperature drift, noise reduction or baseline correction; Adjusting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274—Calibration, base line adjustment, drift correction

Abstract

The invention refers to a Medical test device for the optical determination of a medically important analyte in an aqueous fluid sample, particularly in blood, said test device comprising: a light source (5) for irradiating a sample with primary light (4), a signal lightdetector (10) which provides an analogue measurement signal characterizing the intensity of detected light and which is arranged for detection of secondary light (6) resulting from interaction of primary light (4) with the sample, a base lightdetector (13) which provides an analogue base signal characterizing the intensity of detected light and which is arranged for detection of ambient light (9) , which may contain primary light (4) , analyzing means (15) for analyzing the signals created by the signal lightdetector (10) and the base lightdetector (13) in order to determine the presence and/or concentration of the analyte in the sample. In order to compensate for the part of the measurement signal caused by ambient light (9) , which is detected by the signal lightdetector (10) in addition to secondary light (6) , the signal lightdetector (10) and the base lightdetector (13) are connected to a common line (14) , which leads to the analyzing means (15) , in such a way that the analogue signals created by the lightdetectors (10,13) are subtracted from each other resulting in a compensated analogue signal provided to the analyzing means (15).
PCT/EP2006/005821 2005-07-16 2006-06-17 Medical test device and method for the optical determination of an analyte comprising means for compensating the ambient light background WO2007009541A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200510033327 DE102005033327A1 (en) 2005-07-16 2005-07-16 Medical test device and method for optical analysis of an analyte
DE102005033327.3 2005-07-16

Publications (2)

Publication Number Publication Date
WO2007009541A1 WO2007009541A1 (en) 2007-01-25
WO2007009541A8 true WO2007009541A8 (en) 2007-03-22

Family

ID=36950371

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/005821 WO2007009541A1 (en) 2005-07-16 2006-06-17 Medical test device and method for the optical determination of an analyte comprising means for compensating the ambient light background

Country Status (2)

Country Link
DE (1) DE102005033327A1 (en)
WO (1) WO2007009541A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2335779A1 (en) 2008-08-08 2011-06-22 New York Blood Center Small Molecule Inhibitors of Retroviral Assembly & Maturation
EP2586366B1 (en) 2010-06-24 2016-04-06 Pioneer Corporation Photo-detection device and fluid measurement device
US11747197B2 (en) 2021-09-15 2023-09-05 Endress+Hauser Conducta, Inc. Photometer and method of performing photometric measurements with a photometer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3138879A1 (en) * 1981-09-30 1983-04-14 Boehringer Mannheim Gmbh, 6800 Mannheim METHOD FOR DETECTING PHOTOMETRIC SIGNALS AND ARRANGEMENT FOR IMPLEMENTING THE METHOD
US5117099A (en) * 1989-09-01 1992-05-26 Schmidt Terrence C Ambient light rejecting quad photodiode sensor
US5376783A (en) * 1992-09-16 1994-12-27 Ophir Optronics Ltd. Power meter with background subtraction
US5410145A (en) * 1994-02-25 1995-04-25 Coroy; Trenton G. Light detector using reverse biased photodiodes with dark current compensation

Also Published As

Publication number Publication date
DE102005033327A1 (en) 2007-01-25
WO2007009541A1 (en) 2007-01-25

Similar Documents

Publication Publication Date Title
SE0800724L (en) Blood Viscosity Analysis
ATE447355T1 (en) COMBINED DEVICE FOR MEASUREMENT OF BLOOD SUGAR FROM EYE FLUID
ATE438853T1 (en) DIAGNOSTIC TEST APPARATUS
PT1095270E (en) A screening device and method of screening an immunoassay test
WO2006138294A3 (en) Fiber-optic assay apparatus based on phase-shift interferometry
IL155349A0 (en) Analyte concentration determination devices and methods of using the same
EP1359417A3 (en) Devices and methods for analyte concentration determination
EP3432002A8 (en) Blood coagulation analyzer, blood coagulation analysis method, and computer program
WO2007090147A3 (en) Method and apparatus for measurement of optical properties in tissue
WO2020019014A8 (en) Lateral flow assay devices and method of use
WO2006047388A3 (en) Correlation of concurrent non-invasively acquired signals
WO2010045949A3 (en) Apparatus and methods for analysing fluorescent particles
DE602007011014D1 (en) Immunoassay test device and method of use therefor
WO2009120600A3 (en) Method and system for non-invasive blood glucose detection utilizing spectral data of one or more components other than glucose
EP2430981A4 (en) Blood vessel inner wall analyzing device and blood vessel inner wall analyzing method
WO2008070865A3 (en) Materials and methods for efficient and accurate detection of analytes
EP1894520A3 (en) Body fat measurement apparatus and method of operating the apparatus
WO2005077061A3 (en) Selectivity enhancement in photoacoustic gas analysis via phase-sensitive detection at high modulation frequency
WO2007109710A3 (en) Optical device for detecting live insect infestation
WO2005012553A3 (en) Optical in vivo probe of analyte concentration within the sterile matrix under the human nail
KR100711046B1 (en) Use of nicotinamide n-methyltransferase as a marker for colorectal cancer
WO2010083204A3 (en) Noninvasive measurement of flavonoid compounds in biological tissue
BRPI1014846A8 (en) "surface plasmon resonance detection method and system"
ATE412772T1 (en) FLUORESCENCE SPECTROSCOPY IN ABSORBING MEDIA
MX369024B (en) Reducing optical interference in a fluidic device.

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase in:

Ref country code: DE

WWW Wipo information: withdrawn in national office

Country of ref document: DE

122 Ep: pct application non-entry in european phase

Ref document number: 06754420

Country of ref document: EP

Kind code of ref document: A1