WO2007009457A3 - Identification of protein ligands modifying a cellular response - Google Patents
Identification of protein ligands modifying a cellular response Download PDFInfo
- Publication number
- WO2007009457A3 WO2007009457A3 PCT/DK2006/000410 DK2006000410W WO2007009457A3 WO 2007009457 A3 WO2007009457 A3 WO 2007009457A3 DK 2006000410 W DK2006000410 W DK 2006000410W WO 2007009457 A3 WO2007009457 A3 WO 2007009457A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cellular response
- identification
- modifying
- protein ligands
- screening
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Abstract
The present invention relates to a method for identifying protein ligands capable of modulating a cellular response. The method furthermore enables identification of the protein(s) binding to the identified ligand. The method may in particular be useful in drug screening processes and allows screening for biological activity and for drug targets in a high through-put screening format.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200501068 | 2005-07-18 | ||
DKPA200501068 | 2005-07-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007009457A2 WO2007009457A2 (en) | 2007-01-25 |
WO2007009457A3 true WO2007009457A3 (en) | 2007-05-24 |
Family
ID=37159296
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DK2006/000410 WO2007009457A2 (en) | 2005-07-18 | 2006-07-12 | Identification of protein ligands modifying a cellular response |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2007009457A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2472563B (en) * | 2009-04-28 | 2013-02-27 | Univ Leicester | Method of preparing hairpin and cyclic polyamides |
EP2454269A4 (en) * | 2009-07-15 | 2013-03-06 | Agency Science Tech & Res | Improved screening of biopolymers |
WO2011010964A1 (en) | 2009-07-22 | 2011-01-27 | Agency For Science, Technology And Research | Differentiation of isobaric amino acids and other species |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005045430A1 (en) * | 2003-10-08 | 2005-05-19 | The Regents Of The University Of California | Screening combinatorial bead libraries for cancer ligands |
WO2005116643A2 (en) * | 2004-05-25 | 2005-12-08 | Carlsberg A/S | Identification of compounds modifying a cellular response |
-
2006
- 2006-07-12 WO PCT/DK2006/000410 patent/WO2007009457A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005045430A1 (en) * | 2003-10-08 | 2005-05-19 | The Regents Of The University Of California | Screening combinatorial bead libraries for cancer ligands |
WO2005116643A2 (en) * | 2004-05-25 | 2005-12-08 | Carlsberg A/S | Identification of compounds modifying a cellular response |
WO2005116656A1 (en) * | 2004-05-25 | 2005-12-08 | 2Curex | Identification of compounds modifying a cellular response |
Non-Patent Citations (3)
Title |
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AINA OLULANU H ET AL: "Identification of novel targeting peptides for human ovarian cancer cells using "one-bead one-compound" combinatorial libraries.", MOLECULAR CANCER THERAPEUTICS. MAY 2005, vol. 4, no. 5, May 2005 (2005-05-01), pages 806 - 813, XP002405735, ISSN: 1535-7163 * |
PETERS JENNIFER L ET AL: "Melatonin modulates intercellular communication among cultured chick astrocytes.", BRAIN RESEARCH. 7 JAN 2005, vol. 1031, no. 1, 7 January 2005 (2005-01-07), pages 10 - 19, XP002405734, ISSN: 0006-8993 * |
REZAEE MEHRDAD ET AL: "Del1 mediates VSMC adhesion, migration, and proliferation through interaction with integrin alpha(v)beta(3).", AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. MAY 2002, vol. 282, no. 5, May 2002 (2002-05-01), pages H1924 - H1932, XP002405733, ISSN: 0363-6135 * |
Also Published As
Publication number | Publication date |
---|---|
WO2007009457A2 (en) | 2007-01-25 |
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