WO2007005787A3 - Methods and compositions for keratinocyte culture and therapeutics - Google Patents

Methods and compositions for keratinocyte culture and therapeutics Download PDF

Info

Publication number
WO2007005787A3
WO2007005787A3 PCT/US2006/025907 US2006025907W WO2007005787A3 WO 2007005787 A3 WO2007005787 A3 WO 2007005787A3 US 2006025907 W US2006025907 W US 2006025907W WO 2007005787 A3 WO2007005787 A3 WO 2007005787A3
Authority
WO
WIPO (PCT)
Prior art keywords
collagenase
methods
compositions
therapeutics
keratinocyte culture
Prior art date
Application number
PCT/US2006/025907
Other languages
French (fr)
Other versions
WO2007005787A2 (en
Inventor
Rodolfo Faudoa
Maria L Medina
Original Assignee
Elfamed Inc
Rodolfo Faudoa
Maria L Medina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/257,928 external-priority patent/US20070003541A1/en
Priority claimed from US11/257,927 external-priority patent/US20070128685A1/en
Priority claimed from US11/257,573 external-priority patent/US20070004036A1/en
Application filed by Elfamed Inc, Rodolfo Faudoa, Maria L Medina filed Critical Elfamed Inc
Publication of WO2007005787A2 publication Critical patent/WO2007005787A2/en
Publication of WO2007005787A3 publication Critical patent/WO2007005787A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629—Keratinocytes; Whole skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere

Abstract

The invention encompasses composition and methods for cell culture and for therapeutic and cosmetic use. The compositions and methods utilize collagenase, e.g., bacterial collagenase, other isolated collagenase, or synthetic collagenase, e.g., recombinant collagenase. One form of collagenase that can be used in some embodiments of the invention is matrix metalloproteinase-1. The compositions and methods of the invention also optionally utilize a cAMP-elevating agent.
PCT/US2006/025907 2005-07-01 2006-06-30 Methods and compositions for keratinocyte culture and therapeutics WO2007005787A2 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US69595605P 2005-07-01 2005-07-01
US60/695,956 2005-07-01
US11/257,927 2005-10-24
US11/257,928 US20070003541A1 (en) 2005-07-01 2005-10-24 Methods and compositions for therapeutics
US11/257,573 2005-10-24
US11/257,928 2005-10-24
US11/257,927 US20070128685A1 (en) 2005-07-01 2005-10-24 Methods and compositions for cell culture
US11/257,573 US20070004036A1 (en) 2005-07-01 2005-10-24 Methods and compositions for keratinocyte culture

Publications (2)

Publication Number Publication Date
WO2007005787A2 WO2007005787A2 (en) 2007-01-11
WO2007005787A3 true WO2007005787A3 (en) 2009-04-23

Family

ID=37605118

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/025907 WO2007005787A2 (en) 2005-07-01 2006-06-30 Methods and compositions for keratinocyte culture and therapeutics

Country Status (1)

Country Link
WO (1) WO2007005787A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0613856D0 (en) * 2006-07-13 2006-08-23 Isis Innovation Method for reducing spasms
CN110358723A (en) * 2019-05-08 2019-10-22 广州医科大学附属第二医院 A kind of fibroblastic cultural method of adult mouse heart
KR102560183B1 (en) * 2021-02-09 2023-07-27 한국과학기술원 Medium composition of cell culture for enhancing medical protein production and method of producing medical protein using the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6692961B1 (en) * 1996-10-11 2004-02-17 Invitrogen Corporation Defined systems for epithelial cell culture and use thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6692961B1 (en) * 1996-10-11 2004-02-17 Invitrogen Corporation Defined systems for epithelial cell culture and use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
RILEY ET AL.: "Collagenase Promotes the Cellular Responses to Injury and Wound Healing In Vivo.", JOURNAL OF BUMS AND WOUNDS, vol. 4, May 2005 (2005-05-01), pages 112 - 124 *
TEMPLETON ET AL.: "Cloning and Characterization of Human Tumor Interstitial Collagenase.", CANCER RESEARCH, vol. 50, September 1990 (1990-09-01), pages 5431 - 5437 *

Also Published As

Publication number Publication date
WO2007005787A2 (en) 2007-01-11

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