WO2007005715A3 - Staphylococcal antibodies which cross-react with fungal antigens - Google Patents

Staphylococcal antibodies which cross-react with fungal antigens Download PDF

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Publication number
WO2007005715A3
WO2007005715A3 PCT/US2006/025782 US2006025782W WO2007005715A3 WO 2007005715 A3 WO2007005715 A3 WO 2007005715A3 US 2006025782 W US2006025782 W US 2006025782W WO 2007005715 A3 WO2007005715 A3 WO 2007005715A3
Authority
WO
WIPO (PCT)
Prior art keywords
cross
antibodies
react
fungal antigens
staphylococcal antibodies
Prior art date
Application number
PCT/US2006/025782
Other languages
French (fr)
Other versions
WO2007005715A2 (en
Inventor
Joseph M Patti
Yule Liu
John Vernachio
Jeff T Hutchins
Original Assignee
Inhibtex Inc
Joseph M Patti
Yule Liu
John Vernachio
Jeff T Hutchins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inhibtex Inc, Joseph M Patti, Yule Liu, John Vernachio, Jeff T Hutchins filed Critical Inhibtex Inc
Publication of WO2007005715A2 publication Critical patent/WO2007005715A2/en
Publication of WO2007005715A3 publication Critical patent/WO2007005715A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/14—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from fungi, algea or lichens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Abstract

Cross-reactive antibodies are provided which can recognize antigens from Staphylococcus epidermidis such as the SdrG protein and from Candida albicans, such the Hsp70 protein. These antibodies will thus be useful in methods of treating or preventing infections from Staphylococcus and Candida microorganisms at the same time. Compositions and kits containing these antibodies as well as methods for their use are also provided.
PCT/US2006/025782 2005-07-01 2006-07-03 Staphylococcal antibodies which cross-react with fungal antigens WO2007005715A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US69544105P 2005-07-01 2005-07-01
US60/695,441 2005-07-01
US77287106P 2006-02-14 2006-02-14
US60/772,871 2006-02-14

Publications (2)

Publication Number Publication Date
WO2007005715A2 WO2007005715A2 (en) 2007-01-11
WO2007005715A3 true WO2007005715A3 (en) 2009-04-16

Family

ID=37605080

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/025782 WO2007005715A2 (en) 2005-07-01 2006-07-03 Staphylococcal antibodies which cross-react with fungal antigens

Country Status (1)

Country Link
WO (1) WO2007005715A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6699677B1 (en) * 1999-12-20 2004-03-02 Chemocentryx, Inc. Tethered ligands and methods of use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6699677B1 (en) * 1999-12-20 2004-03-02 Chemocentryx, Inc. Tethered ligands and methods of use

Also Published As

Publication number Publication date
WO2007005715A2 (en) 2007-01-11

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