WO2006131783A3 - Polynucleotides, polypeptides, and diagnosing lung cancer - Google Patents

Polynucleotides, polypeptides, and diagnosing lung cancer Download PDF

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Publication number
WO2006131783A3
WO2006131783A3 PCT/IB2005/004037 IB2005004037W WO2006131783A3 WO 2006131783 A3 WO2006131783 A3 WO 2006131783A3 IB 2005004037 W IB2005004037 W IB 2005004037W WO 2006131783 A3 WO2006131783 A3 WO 2006131783A3
Authority
WO
WIPO (PCT)
Prior art keywords
lung cancer
markers
polynucleotides
polypeptides
diagnosing lung
Prior art date
Application number
PCT/IB2005/004037
Other languages
French (fr)
Other versions
WO2006131783A2 (en
Inventor
Sarah Pollock
Zurit Levine
Amit Novik
Dvir Dahary
Rotem Sorek
Amir Toporik
Shirley Sameah-Greenwald
Osnat Sella-Tavor
Alexander Diber
Gad S. Cojocaru
Michal Ayalon-Soffer
Shira Walach
Pinchas Akiva
Naomi Keren
Ronen Shemesh
Original Assignee
Compugen Usa, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Compugen Usa, Inc. filed Critical Compugen Usa, Inc.
Priority to JP2007519922A priority Critical patent/JP2008507261A/en
Priority to CA002555509A priority patent/CA2555509A1/en
Priority to AU2005320352A priority patent/AU2005320352A1/en
Priority to EP05857765A priority patent/EP1774046A4/en
Priority claimed from US11/051,720 external-priority patent/US7569662B2/en
Publication of WO2006131783A2 publication Critical patent/WO2006131783A2/en
Publication of WO2006131783A3 publication Critical patent/WO2006131783A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification

Abstract

Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.
PCT/IB2005/004037 2004-01-27 2005-01-27 Polynucleotides, polypeptides, and diagnosing lung cancer WO2006131783A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2007519922A JP2008507261A (en) 2004-01-27 2005-01-27 Novel nucleotide and amino acid sequences for lung cancer diagnosis, and assays and methods of use thereof
CA002555509A CA2555509A1 (en) 2004-01-27 2005-01-27 Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer
AU2005320352A AU2005320352A1 (en) 2004-01-27 2005-01-27 Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer
EP05857765A EP1774046A4 (en) 2004-01-27 2005-01-27 Novel nucleotide and amino acid sequences and assays and methods of use thereof for diagnosis of lung cancer

Applications Claiming Priority (62)

Application Number Priority Date Filing Date Title
US53912804P 2004-01-27 2004-01-27
US53912904P 2004-01-27 2004-01-27
US60/539,128 2004-01-27
US60/539,129 2004-01-27
US58981504P 2004-07-22 2004-07-22
US60/589,815 2004-07-22
US60730704P 2004-09-07 2004-09-07
US60/607,307 2004-09-07
US62091604P 2004-10-22 2004-10-22
US62092404P 2004-10-22 2004-10-22
US62067704P 2004-10-22 2004-10-22
US62087404P 2004-10-22 2004-10-22
US62086804P 2004-10-22 2004-10-22
US62097404P 2004-10-22 2004-10-22
US62091704P 2004-10-22 2004-10-22
US62097504P 2004-10-22 2004-10-22
US62100404P 2004-10-22 2004-10-22
US62091804P 2004-10-22 2004-10-22
US62085304P 2004-10-22 2004-10-22
US62065604P 2004-10-22 2004-10-22
US60/620,677 2004-10-22
US60/620,874 2004-10-22
US60/620,917 2004-10-22
US60/620,853 2004-10-22
US60/620,918 2004-10-22
US60/620,974 2004-10-22
US60/620,975 2004-10-22
US60/620,656 2004-10-22
US60/620,868 2004-10-22
US60/620,924 2004-10-22
US60/620,916 2004-10-22
US60/621,004 2004-10-22
US62113104P 2004-10-25 2004-10-25
US62105304P 2004-10-25 2004-10-25
US60/621,053 2004-10-25
US60/621,131 2004-10-25
US62810104P 2004-11-17 2004-11-17
US62813404P 2004-11-17 2004-11-17
US62811104P 2004-11-17 2004-11-17
US62811204P 2004-11-17 2004-11-17
US62814504P 2004-11-17 2004-11-17
US62817804P 2004-11-17 2004-11-17
US62812304P 2004-11-17 2004-11-17
US62818904P 2004-11-17 2004-11-17
US62815604P 2004-11-17 2004-11-17
US62825104P 2004-11-17 2004-11-17
US62816704P 2004-11-17 2004-11-17
US60/628,145 2004-11-17
US60/628,123 2004-11-17
US60/628,178 2004-11-17
US60/628,189 2004-11-17
US60/628,101 2004-11-17
US60/628,156 2004-11-17
US60/628,111 2004-11-17
US60/628,112 2004-11-17
US60/628,134 2004-11-17
US60/628,251 2004-11-17
US60/628,167 2004-11-17
US63407504P 2004-12-08 2004-12-08
US60/634,075 2004-12-08
US11/051,720 US7569662B2 (en) 2004-01-27 2005-01-27 Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer
US11/051,720 2005-01-27

Publications (2)

Publication Number Publication Date
WO2006131783A2 WO2006131783A2 (en) 2006-12-14
WO2006131783A3 true WO2006131783A3 (en) 2009-08-27

Family

ID=37450522

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/004037 WO2006131783A2 (en) 2004-01-27 2005-01-27 Polynucleotides, polypeptides, and diagnosing lung cancer

Country Status (5)

Country Link
EP (1) EP1774046A4 (en)
JP (1) JP2008507261A (en)
AU (1) AU2005320352A1 (en)
CA (1) CA2555509A1 (en)
WO (1) WO2006131783A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2590751A1 (en) 2004-12-13 2006-06-22 Roy Rabindranauth Sooknanan Polynucleotides and polypeptide sequences involved in the process of bone remodeling
CN114835812A (en) 2008-12-09 2022-08-02 霍夫曼-拉罗奇有限公司 anti-PD-L1 antibodies and their use for enhancing T cell function
KR101403019B1 (en) 2013-02-25 2014-06-03 서울대학교산학협력단 Novel biomarker for the diagnosis of lung cancer
CN114804550B (en) * 2022-06-10 2023-06-02 安徽新宇环保科技股份有限公司 Sewage treatment regulation and control system based on neural network model
CN115894942B (en) * 2022-11-07 2024-01-12 同济大学 Hyperbranched comb-type polylysine modified by polycaprolactone and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251386B1 (en) * 1997-08-14 2001-06-26 Novo Nordisk A/S Antimicrobial composition containing a haloperoxidase, a hydrogen peroxide source, a halide source and an ammonium source

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030170255A1 (en) * 1999-06-30 2003-09-11 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
JP2004512824A (en) * 2000-07-11 2004-04-30 コリクサ　コーポレイション Compositions and methods for treatment and diagnosis of lung cancer
CA2444691A1 (en) * 2001-04-18 2002-10-31 Protein Design Labs, Inc. Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
US7705120B2 (en) * 2001-06-21 2010-04-27 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
WO2003097666A2 (en) * 2002-05-16 2003-11-27 Euro-Celtique, S.A. Use of gastrin releasing peptide (grp) and its receptor in cancer screening

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251386B1 (en) * 1997-08-14 2001-06-26 Novo Nordisk A/S Antimicrobial composition containing a haloperoxidase, a hydrogen peroxide source, a halide source and an ammonium source

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1774046A4 *

Also Published As

Publication number Publication date
JP2008507261A (en) 2008-03-13
WO2006131783A2 (en) 2006-12-14
AU2005320352A2 (en) 2006-08-31
AU2005320352A1 (en) 2006-08-31
AU2005320352A8 (en) 2009-04-30
EP1774046A2 (en) 2007-04-18
CA2555509A1 (en) 2005-07-27
EP1774046A4 (en) 2010-09-15

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