WO2006130049A2 - Method for emigraphic diagnosing of organism state and 'emigraph' apparatus - Google Patents
Method for emigraphic diagnosing of organism state and 'emigraph' apparatus Download PDFInfo
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- WO2006130049A2 WO2006130049A2 PCT/RU2006/000280 RU2006000280W WO2006130049A2 WO 2006130049 A2 WO2006130049 A2 WO 2006130049A2 RU 2006000280 W RU2006000280 W RU 2006000280W WO 2006130049 A2 WO2006130049 A2 WO 2006130049A2
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- 238000000034 method Methods 0.000 title claims abstract description 39
- 210000000056 organ Anatomy 0.000 claims abstract description 16
- 238000012545 processing Methods 0.000 claims abstract description 15
- 210000004907 gland Anatomy 0.000 claims abstract description 11
- 238000004458 analytical method Methods 0.000 claims abstract description 10
- 230000007170 pathology Effects 0.000 claims abstract description 10
- 230000005670 electromagnetic radiation Effects 0.000 claims abstract description 7
- 208000037273 Pathologic Processes Diseases 0.000 claims abstract description 6
- 238000001914 filtration Methods 0.000 claims abstract description 6
- 230000009054 pathological process Effects 0.000 claims abstract description 6
- 230000001575 pathological effect Effects 0.000 claims abstract description 4
- 230000000977 initiatory effect Effects 0.000 claims abstract 2
- 238000005259 measurement Methods 0.000 claims description 7
- 230000010355 oscillation Effects 0.000 claims description 2
- 238000000611 regression analysis Methods 0.000 claims description 2
- 238000012731 temporal analysis Methods 0.000 claims description 2
- 238000000700 time series analysis Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 4
- 238000011160 research Methods 0.000 abstract description 4
- 208000035473 Communicable disease Diseases 0.000 abstract description 3
- 230000005672 electromagnetic field Effects 0.000 abstract description 3
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- 230000002269 spontaneous effect Effects 0.000 abstract description 2
- 230000003612 virological effect Effects 0.000 abstract description 2
- 230000003466 anti-cipated effect Effects 0.000 abstract 1
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- 238000001228 spectrum Methods 0.000 description 6
- 230000003321 amplification Effects 0.000 description 3
- 238000013459 approach Methods 0.000 description 3
- 238000003199 nucleic acid amplification method Methods 0.000 description 3
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- 208000017604 Hodgkin disease Diseases 0.000 description 1
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- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000003855 cell nucleus Anatomy 0.000 description 1
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- 210000004720 cerebrum Anatomy 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
- A61B5/0086—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters using infrared radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/415—Evaluating particular organs or parts of the immune or lymphatic systems the glands, e.g. tonsils, adenoids or thymus
Definitions
- the invention relates to a medicine technique and can be used for human organism diagnostics.
- Emigraph and method provide diagnostics the state of organs and glands in a non-invasive way and without any negative effect to the biological subject by means of electromagnetic radiation; it assists to reveal the nature and the degree of pathology as well as to define cause-and-effect relations of the pathology progress within one measurement.
- the diagnostic results permit to define an optimized therapeutic approach and methods of the biological subject correction. This method is extremely actual in the research field of oncological processes growth, viral and a lot other infectious diseases and in some other pathologies.
- the biological subjects' electro-magnetic radiation research in the radio- frequency range makes it possible to obtain more extensive information about those subjects.
- a lot of the radio-frequency range based medical diagnostic methods are well known and proved their effectivity. These are first of all nuclear and paramagnetic resonance methods, and infra-red range thermal imaging methods, decimeter range deep-laid radiometry in the millimeter range information content waves. It is accustomed to divide between two components of the biological subject electromagnetic radiation: one of which is a thermal one (with the equivalent temperature signals above 0.1 0 C) and a non-thermal (with the equivalent temperature signals below 0.1 0 C). It is natural that this margin is a relative kind and depends on particular assignments to be solved.
- thermal processes in an organism play a great part in METABOLISM, and their registrations provide detection them very effectively at the earliest stages of their indication; due to this fact it benefits several years in advance as compared to results, based on the diagnosis of morphological changes in tissues.
- the special part is played by dynamic parameters of thermal processes in an organism.
- the registration of electromagnetic radiation fields of the non-thermal and the information content level is a definitely new sphere in the biological subjects' research method. Obtaining these data provides making a deeper glance on processes taking place not merely in an organ as a general, but on the cellular level as well, and as a future trend it's going up to processes run in the cell nucleus level.
- the problem of the signal registration of both the thermal level low range and the non-thermal level strikes against a number of complexities that sufficiently hamper the task of obtaining true and reproducible results. It is caused by a noisy (or quasi-noisy) nature of observed signals, plus background interferences and internal noises of the receiver. That is why as a majority cases, these radiometric tasks are solved by means of statistical methods. Both of these tasks are hindered by an a priori uncertainty, which is associated with unknown characteristics of the background, and by unstable parameters of the equipment. In spite of the use of quasi-optimal ways of solving those tasks, from the viewpoint of some criteria, nowadays the problem of a theory for the optimal radiometric reception, taking into account the a priori uncertainty, stays unsettled.
- the suggested method of the emigraphic diagnostics of biological subjects is a kind of the first approach to solving the problem pointed out and permits to acquire definite partial results in the course of emigraphic diagnostics activities.
- High-frequency noise signal detection will definitely disfigure or destroy the non-thermal (information) component of the useful signal
- the state of the biological subject is determined only based on the information obtained from its organs and systems.
- Another well known method is the one based on the information- wave diagnostics and therapy, where it is used information signals received by means of measuring radio signals and spectrums of infralow frequencies of information-type signals, that are inherented in organs and systems of patient, and subsequent analysis and comparison those spectrums with spectrums of wittingly healthy organs (patent RU -Ns 2141785 Cl, 1998.07.24). Disadvantages of this method are similar to those mentioned in Point 1, and besides that the spectrums of useful signals are compared to that of wittingly healthy organs only by a feature the deviation is fixed, but it does not permit to identify the nature of a pathologic process.
- the main point of the invention is a design of Emigraph and a method for the emigraphic diagnosing of the organism state, which registers own spontaneous electromagnetic waves emissions from the surface area of a human body on which a projection to the selected organ or gland is done.
- Two components are registered: thermal and non-thermal one.
- the processing is conducted by the input channel calibration for both the thermal and non-thermal coomponents.
- the calibrated signals are shaped in conformity with expected parameters of the emitted electromagnetic field structure.
- parameters of internal noises of receiver are defined; those ones that distort the emitted electromagnetic parameters of the biological subject body area. After that, parameters of internal noises are used for the optimal correlation of the internal useful signal.
- the technological result of the claimed method and the apparatus design for biological subjects' emigraphic diagnosing is an increase of the validity and the reproducibility of measurement results, and, as a final outcome - it is a diagnostic efficiency increase by means of two electromagnetic field components' measurement, which are the thermal and non-thermal (information) components, and calibration of the input channel and making their optimal correlation processing, and identification of the pathological process nature.
- the claimed technical result is obtained due to the fact that measurements are conducted in the infra-red and/or submillimetric radio waves range using a modulation straight receiver with double modulation by means of special synthesized thermal and non-thermal level intensity signals. Further on, in order to eliminate signal distortion, when it is detected, a multistage down conversion is conducted down to values, which allow their further computer processing; and comparison the calibrated signals with their values at ultrahigh frequencies (UHF) outlet, parameters of internal noises are defined, which are used for the optimal correlational processing of the useful signal.
- UHF ultrahigh frequencies
- Emigraph apparatus consists of the following structural elements (Fig. 1),
- the personal computer software is intended for the visual imaging of the data regarding the biological subject state and for its subsequent processing.
- the method of the emigraphic diagnosing of a biological subject state is realized as the following procedure,
- a patient is seated in an armchair in an anechoic shielded room.
- the receiving antenna of the the modulating selected wavelength band straight receiver is positioned at the distance of 5 to 300 sm. away from the patient body's surface; depending on the type of the antenna - a reflector antenna or a horn antenna.
- the antenna's longitudinal axis must be oriented perpendicularly to the body surface for the required organ or gland plane. The energy emitted from the biological subject zone on capacity proportional during each moment of time to its thermodynamic temperature, is received by the antenna.
- the part of energy is reflected from the antenna and fades in the space environment; and the rest of it is transmitted to the Antenna Radiometer System 1 and is further transmitted to directional couplers 2 and 3, assigned to be transmitted to primary thermal and non-thermal level channels by means of the Attenuators 4 and 5, which are controlled by the personal computer, that modify capacity of the 6 and 7 Generators.
- the structure of synthesized calibrated signals is determined according to the type of the assignment the diagnosing is supposed to solve. After that, calibrated and useful signals are transmitted through two independent channels of Band-pass filters 8 and 9, High frequency amplification units 10 and 11, Frequency down-convertion devices 12 and 13 to reduce it down to the level required for the reliable interface operation, as well as system and applicated computer programs.
- the suggested emigraphic diagnosing method has confirmed a high degree of the diagnostic validity and the reproducibility of results when making special tests.
Abstract
The present invention relates to a medical techniques and can be used for diagnostics of human organism state. The general idea of the invention is a method of emigraphic researches of the biological subject state at which is registered own spontaneous electromagnetic radiation emitted from the body area with the projection of the selected organ or gland. Two components are registered: a thermal (equivalent temperature signals more than 0.10C) and non thermal or information (equivalent temperature signals below 0.10C). The processing is conducted using input channel calibration through the thermal and non thermal components. Within the framework of this the signals are calibrated in accordance with the anticipated values of the emitted electromagnetic field. After that, making a comparison of synthesized calibrated signals with the calibrated signals which have passed the input channel, receiver internal noises parameters are defined, which distort parameters of the electromagnetic structure, emitted from the human body area. After that the internal noises parameters are used for an optimal correlation processing of the input useful signal. Further on, using a wave structures resonant searching analysis methods at limited centered slidings with minimal shift lengthways control process intervals, quasi-harmonic components are reconstructed (modified wavelet analysis) and non periodic wave structures owing to the excessive volume of information and adapted filtration. In addition to that, in order to eliminate unaccounted processed artefacts at the beginning stage, a cubical spline- interpolation is accomplished and/or multiscale filtration with symmetric non- recursive filters utilized. Calculated dynamic parameters of the thermal and non thermal components are compared with basic (reference) parameters, and it is estimated a pathological degree of organ or gland and a nature of this pathology. After the diagnostics of state of selected organ of gland it is conducted a combined analysis to define a cause-and-reason correlations initiation and a pathological process expansion. The method permits impartially and without any effect to an organism to diagnostics of organ of gland state non-invasively, and reveal the degree and the nature of pathology as well as to estimate cause-and-reason correlations of this pathology. This circumstance is a most actual one in the field of oncological processes, viral and some other infectious diseases, as well as a number of other pathologies. Diagnosing results permit to select an optimal treatment tactics and correcting methods of the biological subject state. 1 - Radiometer, 2 and 3 - Calibrating directional couplers of the thermal and non-thermal levels, 4 and 5 - Attenuators controlled by a PC, 6 and 7 - Generators, 8 and 9 - Band-pass filters, 10 and 11 - High frequency amplifier units, 12 and 13 - Downconvertion device to the level required for the dependable interface and the computer system applied programs operation, 14 and 15 - Downconvertion device after ADC-DAC, PC - personal computer.
Description
Method for emigraphic diagnosing of organism state and "Emigraph" apparatus
Technical field
The invention relates to a medicine technique and can be used for human organism diagnostics. Emigraph and method provide diagnostics the state of organs and glands in a non-invasive way and without any negative effect to the biological subject by means of electromagnetic radiation; it assists to reveal the nature and the degree of pathology as well as to define cause-and-effect relations of the pathology progress within one measurement. The diagnostic results permit to define an optimized therapeutic approach and methods of the biological subject correction. This method is extremely actual in the research field of oncological processes growth, viral and a lot other infectious diseases and in some other pathologies.
Background of the invention
The biological subjects' electro-magnetic radiation research in the radio- frequency range makes it possible to obtain more extensive information about those subjects. A lot of the radio-frequency range based medical diagnostic methods are well known and proved their effectivity. These are first of all nuclear and paramagnetic resonance methods, and infra-red range thermal imaging methods, decimeter range deep-laid radiometry in the millimeter range information content waves. It is accustomed to divide between two components of the biological subject electromagnetic radiation: one of which is a thermal one (with the equivalent temperature signals above 0.10C) and a non-thermal (with the equivalent temperature signals below 0.10C). It is natural that this margin is a relative kind and depends on particular assignments to be solved.
It is well known, thermal processes in an organism play a great part in METABOLISM, and their registrations provide detection them very effectively at the earliest stages of their indication; due to this fact it benefits several years
in advance as compared to results, based on the diagnosis of morphological changes in tissues. The special part is played by dynamic parameters of thermal processes in an organism. The registration of electromagnetic radiation fields of the non-thermal and the information content level is a definitely new sphere in the biological subjects' research method. Obtaining these data provides making a deeper glance on processes taking place not merely in an organ as a general, but on the cellular level as well, and as a future trend it's going up to processes run in the cell nucleus level. However, the problem of the signal registration of both the thermal level low range and the non-thermal level strikes against a number of complexities that sufficiently hamper the task of obtaining true and reproducible results. It is caused by a noisy (or quasi-noisy) nature of observed signals, plus background interferences and internal noises of the receiver. That is why as a majority cases, these radiometric tasks are solved by means of statistical methods. Both of these tasks are hindered by an a priori uncertainty, which is associated with unknown characteristics of the background, and by unstable parameters of the equipment. In spite of the use of quasi-optimal ways of solving those tasks, from the viewpoint of some criteria, nowadays the problem of a theory for the optimal radiometric reception, taking into account the a priori uncertainty, stays unsettled. The suggested method of the emigraphic diagnostics of biological subjects is a kind of the first approach to solving the problem pointed out and permits to acquire definite partial results in the course of emigraphic diagnostics activities.
There are two other methods that approach the most closely to the presented method and apparatus of the emigraphic diagnostics activities on a biological subject condition; and they are as follows,
1. There is know a method of the remote noninvasive diagnostics of the biological subject condition by means of measuring its electromagnetic radiation using a highly sensitive receiver of the millimeter and/or decimeter ranges, where processing is conducted by detecting a high-frequency noise signal and
takeoff a low-frequency modulating component. Further a spectral analysis is conducted with an assistance of various spectral smoothing windows, and then systematic components in the spectrums using the nonlinear evaluation method are determined together with subsequent elimination of residual curves in the spectrum assessment with the deduction of the constant component. Hereafter diagnostic criteria are built-up in the form of parameters of systematic and characteristics of residual curves, on which basis the state of a biological subject is determined with the help of the statical and/or neuronet classifier (License No. RU JTs 2144786, 1999.05.28).
Disadvantages of this well known method are as follows,
- Channeling absence of the received signal on the thermal level (with the equivalent temperature signals above 0.10C) and the non-thermal one or the information (with the equivalent temperature signals below 0.10C)3
High-frequency noise signal detection will definitely disfigure or destroy the non-thermal (information) component of the useful signal,
- The absence of the receiving channel calibration on both the thermal and the non-thermal (information) component would not allow to receive the optimal useful signals,
- The signal processing is carried out only by means of the spectrum analysis,
- The state of the biological subject is determined only based on the information obtained from its organs and systems.
2. Another well known method is the one based on the information- wave diagnostics and therapy, where it is used information signals received by means of measuring radio signals and spectrums of infralow frequencies of information-type signals, that are inherented in organs and systems of patient, and subsequent analysis and comparison those spectrums with spectrums of wittingly healthy organs (patent RU -Ns 2141785 Cl, 1998.07.24).
Disadvantages of this method are similar to those mentioned in Point 1, and besides that the spectrums of useful signals are compared to that of wittingly healthy organs only by a feature the deviation is fixed, but it does not permit to identify the nature of a pathologic process.
The main point of the invention is a design of Emigraph and a method for the emigraphic diagnosing of the organism state, which registers own spontaneous electromagnetic waves emissions from the surface area of a human body on which a projection to the selected organ or gland is done. Two components are registered: thermal and non-thermal one. The processing is conducted by the input channel calibration for both the thermal and non-thermal coomponents. At the same time the calibrated signals are shaped in conformity with expected parameters of the emitted electromagnetic field structure. And then, by making a comparison of synthesized calibrated signals with calibrated signals, which have passed the input channel, parameters of internal noises of receiver are defined; those ones that distort the emitted electromagnetic parameters of the biological subject body area. After that, parameters of internal noises are used for the optimal correlation of the internal useful signal.
The technological result of the claimed method and the apparatus design for biological subjects' emigraphic diagnosing is an increase of the validity and the reproducibility of measurement results, and, as a final outcome - it is a diagnostic efficiency increase by means of two electromagnetic field components' measurement, which are the thermal and non-thermal (information) components, and calibration of the input channel and making their optimal correlation processing, and identification of the pathological process nature.
The claimed technical result is obtained due to the fact that measurements are conducted in the infra-red and/or submillimetric radio waves range using a modulation straight receiver with double modulation by means of special synthesized thermal and non-thermal level intensity signals.
Further on, in order to eliminate signal distortion, when it is detected, a multistage down conversion is conducted down to values, which allow their further computer processing; and comparison the calibrated signals with their values at ultrahigh frequencies (UHF) outlet, parameters of internal noises are defined, which are used for the optimal correlational processing of the useful signal.
After that, using resonant searching methods of analysys for wave structures at limited centralized slidings with minimal shift intervals of an observation lenght ways the analyzed process the quasi-harmonic structures are reconstructed (modified wavelet analysis), and non periodic wave structures due to surplus volumes of information and adaptive filtration. In addition to that, with the idea to eliminate unaccounted artefacts at the beginning stage, a cubical spline-interpolation and/or multi-scaled filtration are conducted using symmetric non-recursive filters. Calculated dynamic parameters of the thermal and non-thermal components are compared with basic (reference) parameters and it is estimated a degree of the pathological state of an organ or a gland, as well as the nature of that pathology. After diagnosing state of selected organ or a gland a combined analysis is conducted on the basis of all measurements realized for the purpose of the cause-and-reason correlations of the pathological process origin and its expansion.
Emigraph apparatus consists of the following structural elements (Fig. 1),
1. Antenna system
2. Directional coupler
3. Directional coupler
4. Attenuator
5. Attenuator
6. Generator
7. Generator
8. Band-pass filter
9. Band-pass filter
10. High frequency amplification device
11. High frequency amplification device
12. Downconvertion frequency device
13. Downconvertion frequency device
14. Amplifier
15. Amplifier
- The analog-digital converter - The digital-analog converter (ADC-DAC)
- The personal computer software is intended for the visual imaging of the data regarding the biological subject state and for its subsequent processing.
Sample
The method of the emigraphic diagnosing of a biological subject state is realized as the following procedure,
A patient is seated in an armchair in an anechoic shielded room. The receiving antenna of the the modulating selected wavelength band straight receiver is positioned at the distance of 5 to 300 sm. away from the patient body's surface; depending on the type of the antenna - a reflector antenna or a horn antenna. The antenna's longitudinal axis must be oriented perpendicularly to the body surface for the required organ or gland plane. The energy emitted from the biological subject zone on capacity proportional during each moment of time to its thermodynamic temperature, is received by the antenna. The part of energy is reflected from the antenna and fades in the space environment; and the rest of it is transmitted to the Antenna Radiometer System 1 and is further transmitted to directional couplers 2 and 3, assigned to be transmitted to primary thermal and non-thermal level channels by means of the Attenuators 4 and 5, which are controlled by the personal computer, that modify capacity of the 6 and 7 Generators. Herein the structure of synthesized calibrated signals is determined according to the type of the assignment the diagnosing is supposed to solve. After that, calibrated and useful signals are transmitted through two
independent channels of Band-pass filters 8 and 9, High frequency amplification units 10 and 11, Frequency down-convertion devices 12 and 13 to reduce it down to the level required for the reliable interface operation, as well as system and applicated computer programs. The summary of useful and calibrated signal after down-convertion, after Amplifiers 14 and 15 are transmitted to analog inputs ADC-DAC and further for the subsequent processing by the computer. Then after the time series are recorded by the computer, the useful and calibrated signals are subject to the mathematical processing, as follows,
- The analyses and elimination of the revealed artefacts,
- Sorting out and formation of time series: the useful signal and thermal level calibrated signal and non-thermal level calibrated signal,
- Comparison of the synthesized calibrated signal with the calibrated signal that have passed the input channel bythe way of the sequential sectioning time series analysis.
- Definition of the internal noises structural parameters of the input channel,
- Reconstruction of the useful signal structure together with compensation of input channel internal noises using the step-by-step nonlinear regression analysis method with the use of harmonic oscillations and sliding centering,
- The optimized correlation processing of the thermal and non-thermal level reconstructed useful signals using basis calibrating structures,
- The resonant searching method of analysis for wave structures at limited centered slidings with a minimum shift of intervals longitudinally as to the analyzed process,
- Cubical spline-interpolation and/or multi-scaled filtration with the use of symmetric nonrecursive filters (in case of a necessity),
- Estimation of dynamic parameters of the thermal and non-thermal components, comparing them with basic (reference) parameters and estimation of the pathological state degree of an organ or a gland; and the nature of that pathology,
- A combined analysis to reveal the cause-and-reason correlations of the pathological process expansion.
The following basic (or reference) diagnostic parameters are applied, The normal, Infectious diseases:
- Tuberculosis,
- Salmonellosis,
- E-coli,
- Clamidiosis, Pancreatic diabetes, Leucosis,
Lymphogranulomatosis, Cerebrum diseases,
- Schizophrenia,
- Epilepsy, Oncological processes factors.
The suggested emigraphic diagnosing method has confirmed a high degree of the diagnostic validity and the reproducibility of results when making special tests.
Claims
Claims
A method for emigraphic diagnosing of organism by means of measuring its electromagnetic radiation and subsequent processing and analyzing the measurement results comprising: those measurements are conducted in infrared, submillimetric and radio ranges for thermal (equivalent temperature signals above 0.10C) and non-thermal or information component (equivalent temperature signals below 0.10C) of the emitted signal by using a straight amplifier receiver; the processing is conducted by a comparison of synthesized calibrating signals with calibrating signals, which have passed input channel, using sequential sectioning time series analysis; herewith structural parameters of input channel internal noises are defined, and a useful signal structure with input channel internal noises is reconstructed using a step-by-step nonlinear regression analysis method on areas of harmonic oscillations and sliding centering; after that an optimal correlation processing of the reconstructed thermal and non-thermal level useful signal is conducted using basic calibrating components, and analyzing wave structures at limited centered slidings with the minimal shift in control intervals lengthways the analyzed process; in case of a necessity cubical spline-inter-polation and/or multiscale filtration is conducted with symmetric non-recursive filter utilized; after that dynamic parameters of thermal and non-thermal components are calculated, which are compared with basic parameters, and then a pathological state degree of the examined organ or gland is estimated, as well as a pathology nature, and a combined analysis is conducted to define cause-and-reason correlations initiation and a pathological process expansion.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2005116314 | 2005-05-31 | ||
| RU2005116314/14A RU2005116314A (en) | 2005-05-31 | 2005-05-31 | METHOD FOR EMIGRAPHIC STUDIES OF THE STATE OF BIO OBJECTS AND EMIGRAPH |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2006130049A2 true WO2006130049A2 (en) | 2006-12-07 |
| WO2006130049A3 WO2006130049A3 (en) | 2007-02-08 |
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|---|---|---|---|
| PCT/RU2006/000280 WO2006130049A2 (en) | 2005-05-31 | 2006-05-30 | Method for emigraphic diagnosing of organism state and 'emigraph' apparatus |
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| Country | Link |
|---|---|
| RU (1) | RU2005116314A (en) |
| WO (1) | WO2006130049A2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EA012029B1 (en) * | 2008-02-08 | 2009-06-30 | Общество С Ограниченной Ответственностью "Макена Рус" | Method for diagnosing of human's pathological conditions |
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| RU2141785C1 (en) * | 1998-07-24 | 1999-11-27 | Закрытое акционерное общество НЦИМ "ЛИДО" | Method for carrying out wave information diagnosis and therapy |
| RU2144786C1 (en) * | 1999-05-28 | 2000-01-27 | Авшалумов Александр Шамаилович | Distant control noninvasive method for diagnosing biological object state |
| WO2001005304A1 (en) * | 1999-07-15 | 2001-01-25 | Dobi Medical Systems, Llc | Method of living organism multimodal functional mapping |
| WO2004034231A2 (en) * | 2002-10-11 | 2004-04-22 | Flint Hills Scientific, L.L.C. | Intrinsic timescale decomposition, filtering, and automated analysis of signals of arbitrary origin or timescale |
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2005
- 2005-05-31 RU RU2005116314/14A patent/RU2005116314A/en not_active Application Discontinuation
-
2006
- 2006-05-30 WO PCT/RU2006/000280 patent/WO2006130049A2/en active Application Filing
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5458142A (en) * | 1993-03-19 | 1995-10-17 | Farmer; Edward J. | Device for monitoring a magnetic field emanating from an organism |
| RU2141785C1 (en) * | 1998-07-24 | 1999-11-27 | Закрытое акционерное общество НЦИМ "ЛИДО" | Method for carrying out wave information diagnosis and therapy |
| RU2144786C1 (en) * | 1999-05-28 | 2000-01-27 | Авшалумов Александр Шамаилович | Distant control noninvasive method for diagnosing biological object state |
| WO2001005304A1 (en) * | 1999-07-15 | 2001-01-25 | Dobi Medical Systems, Llc | Method of living organism multimodal functional mapping |
| WO2004034231A2 (en) * | 2002-10-11 | 2004-04-22 | Flint Hills Scientific, L.L.C. | Intrinsic timescale decomposition, filtering, and automated analysis of signals of arbitrary origin or timescale |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2005116314A (en) | 2006-12-10 |
| WO2006130049A3 (en) | 2007-02-08 |
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