WO2006126059A1 - Dispositif de refroidissement - Google Patents

Dispositif de refroidissement Download PDF

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Publication number
WO2006126059A1
WO2006126059A1 PCT/IB2006/001341 IB2006001341W WO2006126059A1 WO 2006126059 A1 WO2006126059 A1 WO 2006126059A1 IB 2006001341 W IB2006001341 W IB 2006001341W WO 2006126059 A1 WO2006126059 A1 WO 2006126059A1
Authority
WO
WIPO (PCT)
Prior art keywords
glove
cooling
temperature
fluid
flow passages
Prior art date
Application number
PCT/IB2006/001341
Other languages
English (en)
Inventor
John Kern
Yvonne Olofsson
Lars Kjaerulff
Original Assignee
Fiomed Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fiomed Aps filed Critical Fiomed Aps
Publication of WO2006126059A1 publication Critical patent/WO2006126059A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/10Cooling bags, e.g. ice-bags
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001Body part
    • A61F2007/0029Arm or parts thereof
    • A61F2007/0036Hand
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001Body part
    • A61F2007/0029Arm or parts thereof
    • A61F2007/0037Finger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001Body part
    • A61F2007/0039Leg or parts thereof
    • A61F2007/0045Foot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001Body part
    • A61F2007/0039Leg or parts thereof
    • A61F2007/0046Toe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0054Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
    • A61F2007/0056Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water for cooling

Definitions

  • the present invention relates to coaling gloves and moccasins to be worn on a human hand and foot, respectively, and more specifically to cooling gloves and moccasins comprising a flowing liquid for cooling the gloves and moccasins to a temperature around 0-5 0 C in order to reduce undesired effects from chemotherapy, e.g. loss of naiis and painful skin reactions.
  • a well-known problem associated with chemotherapy treatment is loss of hair.
  • the side effects of chemotherapy depend on the type of chemotherapy and the amount given. Anticipating and managing side effects can help to minimize them and provide the best possible experience for the person receiving chemotherapy. Many patients who undergo chemotherapy are also surprised to learn that their nails become brittle or discolored, crack easily, or even fall off. The only parts of the human body which continue to grow after adulthood is reached are the hair and nails. In other words, if it needs trimming, there is a risk that it will be affected by chemotherapy. If a nail is lost, it can take 6 months or longer for it to grow back. These nail changes are especially common with chemotherapy such as Taxotere (Docetaxel or paclitaxel) and 5-FU (Fluorouracil).
  • Taxotere Docetaxel or paclitaxel
  • 5-FU Fluorouracil
  • WO 98/16176 discloses an apparatus for regulating the temperature of the scatp of a person undergoing chemotherapy.
  • the apparatus comprises a head covering that includes a plurality of flow passages that extend from the edge of the head covering up towards the crown of said covering.
  • US patent No 5,950,234 discloses a cooling pack in the form of a container encapsulating a cooling substance for preventing loss of hair during chemotherapy treatment.
  • the cooling pack may be formed in a bowl shape to cover the scalp portion of the users head.
  • US patent No 4,765,338 discloses a reusable heat exchanging head piece employable with cancer therapy patients in order to cool the scalp zone of the head for preventing hair loss during chemotherapy treatment.
  • US patent No 4,753,242 discloses a skull helmet, which in use, is worn on the head of a patient and receives circulatory cooling fluid to cool the patient's scalp.
  • the helmet is particularly useful when a patient undergoes chemotherapy.
  • US patent No 5,509,801 discloses an oral therapeutic apparatus comprising an oral device formed to be insertable within a patient's mouth and receiving a circulated cooling medium.
  • US patent No 6,315,696 discloses a therapeutic device for use in the treatment and/or rehabilitation of injuries to bodily extremities, such as the hands or feet.
  • a capsule or chamber is provided which is at least partially filled with a Newtonian or non-Newtonian liquid.
  • An area approximating the shape of the extremity, such as a hand, is formed and made an integral part of the capsule such that the extremity may be inserted to move freely within the liquid physically coming into contact with the liquid.
  • WO 99/47011 discloses a thermal glove fitted to a human hand having integrated with a body of the glove a thermal gel-filled pack.
  • the gel pack includes a sealed bladder constructed of a flexible, durable material resistant to heat and rupture.
  • the bladder encloses a thermal gel adapted for repeated heating and cooling for comfort, prosthetic and/or injury preventive use for technical workers, such as computer users and laboratory workers.
  • the prior art does not describe gloves or moccasins adapted for cooling the fingers and toes, respectively, during chemotherapy treatment.
  • the devices disclosed in US patent No 6,315,696 and WO 99/47011 do not make use of any temperature- regulating means during the treatment period.
  • the devices do not include flow passages causing the cooling fluid to flow in the regions adjacent to the nails, and thus the body temperature would inevitably increase the temperature of the cooling liquid giving rise to less efficient cooling. It should be noted that the most efficient treatment is achieved at temperatures between 0 and 5 0 C; at lower temperatures freeze-injuries will appear, and at higher temperatures the treatment is inefficient.
  • US patent No 5,871,526 discloses a light-weight portable temperature control unit integrating a variety of face and body pads that will conform to the various contours of the face and body to aid in the therapeutic treatment of sports injuries and other forms of trauma.
  • the patent does not envisage a system which would be able to cool all fingers or all toes sufficiently well for being suitable in connection with chemotherapy. Importantly, it fails to constantly and uniformly cool all of the fingers and toes simultaneously.
  • the known methods and apparatus for cooling extremities would either not maintain the skin at a constant desired temperature for the duration of extended treatments or otherwise not be suitable for cooling the entire region, i.e. all fingers or all toes.
  • the present invention comprises an apparatus for reducing the undesired side-effects on extremities of a patient being subjected to a chemotherapy treatment, which comprises a hand or foot therapeutic device having an inner contour that conforms to the patient's hand or foot and contacts the patient's fingers or toes.
  • the device contains a cooling medium, which is preferably circulated therethrough by a supply source, which maintains the cooling medium at the desired temperature to prevent warming of the device for the duration of the chemotherapy treatment.
  • an apparatus for regulating the temperature of a human hand in particular the apical parts thereof, comprising a glove that includes a plurality of flow passages and a cooling fluid which flows through the passages from an inlet and which are connected through an outlet to a circulating system, wherein the flow passages are provided with baffles or the like and a regulating device is provided for regulating the temperature and/or the flow of the fluid flowing through the respective flow passages.
  • the present invention is directed to a system for cooling the hands, in particular the apical parts thereof, of a patient undergoing chemotherapy comprising:
  • -a cooling unit and a pump for supplying the glove with cooling fluid at a predetermined temperature
  • -tubes for transporting the cooling fluid from the cooling unit to the glove wherein the flow passages are connected in serial or parallel, and which extend along the fingers of the glove.
  • the flow passages are connected in serial. This offers a very simple design since the supply of cooling fluid to the glove may be accomplished by virtue of a single tube connected to one end of the glove.
  • the flow passages may be provided with baffles in order to establish a guided flow around the fingers (see e.g. Figure 1). Such baffles have in some cases proven to be decisive for optimum cooling around the fingers, since they may prevent dead volumes, air bubbles and other undesired fluid dynamics.
  • One aspect of the present invention is that the cooling unit and the glove are connected so as to form a circulating system for the cooling fluid.
  • a simple design may have several advantages including low manufacturing cost and facilitates the disconnection of the glove from the cooling unit, However, such a system may also suffer from the fact that the temperature of the cooling fluid increases when it travels from one end of the glove to the other end.
  • the cooling unit of the system may be adapted for regulating the temperature and/or the flow of the fluid flowing through the flow passages.
  • the material of the cooling glove several natural and synthetic polymers are suitable provided that the material exhibits a sufficient degree of elasticity and chemical inertness. Preferred materials include natural rubber and silicone rubber.
  • the system may be made so that the cooling fluid circulates between the glove and the cooling unit.
  • the system may be provided with two sets of quick disconnects, one being coupled by tubes to the cooling unit and the other being coupled to the pump for return of the fluid. In this way the patient may easily and rapidly disintegrate from the cooling unit.
  • the system utilizes water as the cooling fluid kept at a temperature between 0 and 5 0 C 1 more preferably between 2 and 4 ⁇ C, and most preferably between 2.5 and 3.5°C.
  • an apparatus for regulating the temperature of a human foot, in particular the apical parts thereof, comprising a moccasin or shoe that includes a plurality of flow passages and a cooling fluid which flows through the passages from an inlet and which are connected through an outlet to a circulating system, wherein the flow passages are provided with baffles or the like and a regulating device is provided for regulating the temperature and/or the flow of the fluid flowing through the respective flow passages.
  • Figure 1 shows a cooling glove according to a preferred embodiment of the invention.
  • Figure 2 shows a cooling moccasin according to a preferred embodiment of the invention.
  • Figure 1 shows a cooling glove 1 according to a preferred embodiment of the invention.
  • the glove is made of an elastic material so that it will fit to the fingers of the patient and remain in place without being dislodged from the patient should he/she change the position of his/her body during treatment.
  • the glove may also be supplemented with a strap for instance, if so desired.
  • the material from which the glove is made will also be capable of enclosing a cooling fluid intended for circulation between walls embodied in the glove, in the manner described in more detail hereinafter, without the fluid leaking from the glove.
  • the glove is produced from a rubber fabric. It will be understood, however, that this fabric Is only an example of possible materials that can be used and does not constitute a limitation of the scope of the invention. Different types of elastic, impervious materials or coated and therefore densely net- formed material structures can also be used with advantage.
  • the glove includes an inner fabric 2 which lies proximal to the patient's fingers, and externally of the fabric an outer fabric 3,
  • the fabrics define therebetween a space 4 through which cooling fluid shall flow.
  • the fabrics are joined together at their bottom regions around the edge 5 of the glove and along walls 6 defining passages through which the cooling fluid may flow.
  • the walls 6 extend from said edge towards the apices/tips 7 of the glove.
  • the glove thereby defines sections 8 for separately cooling the patient's fingers.
  • an inlet 9 and an outlet 10 for flow connection of the sections and for flow connection of the glove to a cooling unit (not shown).
  • the inlet and outlet of each section may be individually connected to the cooling unit, whereby the sections are connected in parallel. This may have the advantage that each finger is cooled with cooling fluid having a uniform temperature; this may be necessary where the cooling fluid has to be kept at a very low temperature, where serially connected sections are, in some instances, not cooled to the same degree.
  • a temperature sensor may be provided, which monitors the current local temperature.
  • the sensor may be electric and the temperature reading delivered via a cable. This cable may be drawn out of the section through the inlet or the outlet and passed out of the section through the inlet or the outlet and passed out through the conductor wall at an appropriate position.
  • the sensor will preferably lie in abutment with the inner fabric wail 2.
  • the temperature sensor may alternatively be mounted in the interior of the glove, which simplifies the delivery of the information from the temperature sensor and slightly enhances monitoring precision.
  • the sensor may be mounted on or in the inner fabric wall 2, for instance in immediate contact with the head, inwardly of respective sections.
  • This regulation can be effected manually after manually reading the temperatures, or automatically with the aid of an electronic monitoring and regulating means.
  • a desired set point value e.g. +3 0 C can be compared in a computer with current information from the temperature sensors in the respective sections, said computer functioning to initiate adjustment of the cooling effect in each section in relation to the difference.
  • such an apparatus may include a program for regulated cooling.
  • the glove may be at room temperature when placed on the patient's fingers and the patient given the choice of lowering the temperature rapidly or slowly.
  • the glove may be provided externally with an outer insulating guard.
  • This guard may, for instance, include a heat-radiation reflecting and/or a porous insulating material.
  • an outer covering that comprises several layers which include separate air-filled cavities or channels that function to counteract conduction, radiation and convection of heat.
  • a cooling unit may be used for each section (in parallel), so that flow rate and temperature can be regulated individually for each section.
  • the joints can be produced by any means suitable in respect of the material chosen.
  • the joints may be vulcanized or glued.
  • the joints may be glued or welded, e.g. high-frequency welds, etc.
  • the materials will preferably be elastic so as to fit the patient's fingers. Moldabiiity assists in ensuring that the inner wall of the inner fabric of the sections will lie against the whole of the fingers so no part of the fingers go untreated.
  • the cooling fluid used may be any fluid known to the skilled person, in this particular technical field any fluid suitable for the temperature intervals and cooling units concerned.
  • Water is the preferred cooling fluid because it has desirable heat transfer properties; however, other cooling mediums such as solutions of water and alcohol may optionally be used.
  • the cooling medium is maintained at a temperature of approximately 0 0 C to approximately 5 ⁇ C.
  • Figure 2 shows a cooling moccasin according to a preferred embodiment of the invention, with the moccasin applied to a patient's foot for the purpose of cooling the patient's toes.
  • the cooling glove and/or moccasins may be connected to a portable temperature control system (cooling unit).
  • the basic components of a portable temperature control system according to the present invention are means, usually a pump, for circulating the cooling fluid through the temperature control system, and means for cooling the fluid.
  • the system may comprise an electronic programmable temperature controller for minute adjustments of the temperature of the fluid flowing through the system such that the control system can be programmed to provide cooling cycles in any sequence for variable periods of time, a power supply for powering the temperature control system, a keypad connected to the electronic programmable temperature controller for programming the cooling and heating variable periods of time.
  • the temperature control system may also include a liquid crystal display screen for communicating with the machine's operator, and liquid electronic displays.
  • the system preferably comprises a dual output system wherein there is a fixed voltage output for the pump and a programmable voltage for regulating the temperature.
  • the power supply may be a single output DC system and the pump operated from the AC line source.
  • thermoelectric elements preferably utilizes an arrangement of the thermoelectric elements to effect a lightweight portable cooler.
  • These thermoelectric elements or couplers heat or cool depending on the direction of the current flow through the elements (Peltier effect).
  • the cooler is precisely temperature controlled and can be coupled through quick disconnects to the glove or moccasin of the present invention.
  • the programmable temperature controller includes a microprocessor capable of controlling the temperature of the circulating fluid within ⁇ 0.5°C of the preset temperature.
  • the microprocessor of the programmable temperature controller can be programmed to automatically provide heating and cooling cycles in any desired sequence and duration of time.
  • the power supply of the temperature control unit preferably comprises an international front end power supply having a direct current voltage converter adaptable with an international input power supply functional on either 40 to 60 cycles and 90 to 270 volts AC or operational on battery power.
  • the power supply may be an AC power supply, or the temperature control unit may have more than one power supply.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Thermal Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)

Abstract

L'invention concerne un système de refroidissement des mains, en particulier des parties apicales de ces dernières, d'un patient soumis à une chimiothérapie. Ledit système comprend : - un gant adapté aux doigts du patient, ledit gant étant pourvu de passages d'écoulement pour un liquide de refroidissement, - une unité de refroidissement et une pompe destinée à alimenter le gant à l'aide d'un liquide de refroidissement à une température prédéterminée, et - des tubes destinés à transporter le liquide de refroidissement de l'unité de refroidissement au gant, les passages d'écoulement étant reliés en série ou en parallèle et s'étendant le long des doigts du gant.
PCT/IB2006/001341 2005-05-24 2006-05-23 Dispositif de refroidissement WO2006126059A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200500752 2005-05-24
DKPA200500752 2005-05-24

Publications (1)

Publication Number Publication Date
WO2006126059A1 true WO2006126059A1 (fr) 2006-11-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/001341 WO2006126059A1 (fr) 2005-05-24 2006-05-23 Dispositif de refroidissement

Country Status (1)

Country Link
WO (1) WO2006126059A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012020267A1 (fr) 2010-08-13 2012-02-16 Paxman Coolers Limited Appareil de régulation de la température d'une partie de l'organisme
WO2014057450A1 (fr) * 2012-10-10 2014-04-17 Neuron Guard S.R.L.S. Collier thérapeutique
US11141309B2 (en) 2019-06-03 2021-10-12 Cooler Heads Care, Inc. Cooling cap assembly and cooling unit
CN114795642A (zh) * 2022-06-24 2022-07-29 浙江省肿瘤医院 一种冷疗温度控制方法和装置

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2479784A (en) * 1945-01-12 1949-08-23 Colvin Templeton Inc Cold application
US4753242A (en) 1985-01-28 1988-06-28 Saggers Michael J Skull helmet for circulating cooling fluid
US4765338A (en) 1982-12-29 1988-08-23 Turner Richard W Reuseable heat transfer devices for the scalp
DE8715804U1 (de) * 1987-11-29 1989-03-30 Walter, Klaus, 8211 Breitbrunn Vorrichtung zur gezielten Kälte- oder Wärmebehandlung o.ä. erkrankter Gelenke und sonstiger Körperpartien bestehend aus beschickbaren Hohlkörpern
US5509801A (en) 1993-08-02 1996-04-23 Nicholson; James A. Oral therapeutic apparatus for cooling oral tissues
WO1998016176A1 (fr) 1996-10-17 1998-04-23 Yvonne Olofsson Dispositif de refroidissement du cuir chevelu
US5871526A (en) 1993-10-13 1999-02-16 Gibbs; Roselle Portable temperature control system
US5950234A (en) 1997-03-31 1999-09-14 Leong; Randy Cooling pack head covering
WO1999047011A1 (fr) 1998-03-17 1999-09-23 Consumers Choice Systems, Inc. Gant thermique
US6315696B1 (en) 1997-01-30 2001-11-13 Robin Goldstein Liquid immersion therapeutic device
US20030028948A1 (en) * 2001-06-25 2003-02-13 Chambers Paul A. Personal cooling or warming system using closed loop fluid flow
NL1025362C1 (nl) * 2004-01-30 2005-08-02 Jacoba Bijl Inrichting en werkwijze voor het behandelen van de uiteinden van de ledematen van patienten.

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2479784A (en) * 1945-01-12 1949-08-23 Colvin Templeton Inc Cold application
US4765338A (en) 1982-12-29 1988-08-23 Turner Richard W Reuseable heat transfer devices for the scalp
US4753242A (en) 1985-01-28 1988-06-28 Saggers Michael J Skull helmet for circulating cooling fluid
DE8715804U1 (de) * 1987-11-29 1989-03-30 Walter, Klaus, 8211 Breitbrunn Vorrichtung zur gezielten Kälte- oder Wärmebehandlung o.ä. erkrankter Gelenke und sonstiger Körperpartien bestehend aus beschickbaren Hohlkörpern
US5509801A (en) 1993-08-02 1996-04-23 Nicholson; James A. Oral therapeutic apparatus for cooling oral tissues
US5871526A (en) 1993-10-13 1999-02-16 Gibbs; Roselle Portable temperature control system
WO1998016176A1 (fr) 1996-10-17 1998-04-23 Yvonne Olofsson Dispositif de refroidissement du cuir chevelu
US6315696B1 (en) 1997-01-30 2001-11-13 Robin Goldstein Liquid immersion therapeutic device
US5950234A (en) 1997-03-31 1999-09-14 Leong; Randy Cooling pack head covering
WO1999047011A1 (fr) 1998-03-17 1999-09-23 Consumers Choice Systems, Inc. Gant thermique
US20030028948A1 (en) * 2001-06-25 2003-02-13 Chambers Paul A. Personal cooling or warming system using closed loop fluid flow
NL1025362C1 (nl) * 2004-01-30 2005-08-02 Jacoba Bijl Inrichting en werkwijze voor het behandelen van de uiteinden van de ledematen van patienten.

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012020267A1 (fr) 2010-08-13 2012-02-16 Paxman Coolers Limited Appareil de régulation de la température d'une partie de l'organisme
WO2014057450A1 (fr) * 2012-10-10 2014-04-17 Neuron Guard S.R.L.S. Collier thérapeutique
US9622904B2 (en) 2012-10-10 2017-04-18 Neuron Guard S.R.L. Therapeutic collar
US11141310B2 (en) 2012-10-10 2021-10-12 Neuron Guard S.R.L. Method for inducing hypothermia in a patient
US11141309B2 (en) 2019-06-03 2021-10-12 Cooler Heads Care, Inc. Cooling cap assembly and cooling unit
US11622881B2 (en) 2019-06-03 2023-04-11 Cooler Heads Care, Inc. Cooling cap assembly and cooling unit
CN114795642A (zh) * 2022-06-24 2022-07-29 浙江省肿瘤医院 一种冷疗温度控制方法和装置
CN114795642B (zh) * 2022-06-24 2022-10-18 浙江省肿瘤医院 一种冷疗温度控制方法和装置

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