WO2006124888A3 - Detection of antigen specific immunocomplexes - Google Patents

Detection of antigen specific immunocomplexes Download PDF

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Publication number
WO2006124888A3
WO2006124888A3 PCT/US2006/018902 US2006018902W WO2006124888A3 WO 2006124888 A3 WO2006124888 A3 WO 2006124888A3 US 2006018902 W US2006018902 W US 2006018902W WO 2006124888 A3 WO2006124888 A3 WO 2006124888A3
Authority
WO
WIPO (PCT)
Prior art keywords
detection
antigen specific
specific immunocomplexes
immunocomplexes
detecting
Prior art date
Application number
PCT/US2006/018902
Other languages
French (fr)
Other versions
WO2006124888A2 (en
Inventor
Daniel C Dantini
Brent Dorval
Original Assignee
Brendan Bioscience Llc
Daniel C Dantini
Brent Dorval
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brendan Bioscience Llc, Daniel C Dantini, Brent Dorval filed Critical Brendan Bioscience Llc
Publication of WO2006124888A2 publication Critical patent/WO2006124888A2/en
Publication of WO2006124888A3 publication Critical patent/WO2006124888A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention relates to methods and devices for detecting biological entities and components associated with hypersensitivity reactions in patients with allergies, cancer or autoimmune disease. Specifically, the assays of the invention are capable of qualitatively and/or quantitatively detecting allergen specific immunocomplexes by assaying for immobilized C3b in a biological sample produced as a result of exposure to food.
PCT/US2006/018902 2005-05-16 2006-05-16 Detection of antigen specific immunocomplexes WO2006124888A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68115405P 2005-05-16 2005-05-16
US60/681,154 2005-05-16

Publications (2)

Publication Number Publication Date
WO2006124888A2 WO2006124888A2 (en) 2006-11-23
WO2006124888A3 true WO2006124888A3 (en) 2007-05-24

Family

ID=37432032

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/018902 WO2006124888A2 (en) 2005-05-16 2006-05-16 Detection of antigen specific immunocomplexes

Country Status (1)

Country Link
WO (1) WO2006124888A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011332241B2 (en) * 2010-11-02 2015-11-26 Kypha, Inc. Lateral flow immunoassay for complement activation and methods of use for point-of-care assessment of complement-associated disorders
US8865164B2 (en) 2010-11-02 2014-10-21 Kypha, Inc. Detecting complement activation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960712A (en) * 1983-11-15 1990-10-02 Scripps Clinic And Research Foundation System and method for complement pathway analysis
WO2005078442A1 (en) * 2004-02-10 2005-08-25 Dantini Daniel C Comprehensive food allergy test

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960712A (en) * 1983-11-15 1990-10-02 Scripps Clinic And Research Foundation System and method for complement pathway analysis
WO2005078442A1 (en) * 2004-02-10 2005-08-25 Dantini Daniel C Comprehensive food allergy test

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BUNNAG C ET AL: "A PRELIMINARY STUDY OF CIRCULATING IMMUNE COMPLEXES DURING ALLERGEN IMMUNOTHERAPY IN THAI PATIENTS", ASIAN PACIFIC JOURNAL OF ALLERGY AND IMMUNOLOGY, vol. 7, no. 1, 1989, pages 15 - 22, XP009080768, ISSN: 0125-877X *
IIDA K ET AL: "A SOLID-PHASE ANTI-C3 ASSAY FOR DETECTION OF IMMUNE COMPLEXES IN SIX DISTINGUISHED FORMS", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 98, no. 1, 1987, pages 23 - 28, XP002332792, ISSN: 0022-1759 *

Also Published As

Publication number Publication date
WO2006124888A2 (en) 2006-11-23

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