WO2006117526A3 - Determining the age of skin bruises - Google Patents

Determining the age of skin bruises Download PDF

Info

Publication number
WO2006117526A3
WO2006117526A3 PCT/GB2006/001566 GB2006001566W WO2006117526A3 WO 2006117526 A3 WO2006117526 A3 WO 2006117526A3 GB 2006001566 W GB2006001566 W GB 2006001566W WO 2006117526 A3 WO2006117526 A3 WO 2006117526A3
Authority
WO
WIPO (PCT)
Prior art keywords
injury
haemoglobin
age
bilirubin
spectra
Prior art date
Application number
PCT/GB2006/001566
Other languages
French (fr)
Other versions
WO2006117526A2 (en
Inventor
Lise Lyngsnes Randeberg
Lars Othar Svaasand
Original Assignee
Ntnu Technology Transfer As
Jackson Robert
Lise Lyngsnes Randeberg
Lars Othar Svaasand
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ntnu Technology Transfer As, Jackson Robert, Lise Lyngsnes Randeberg, Lars Othar Svaasand filed Critical Ntnu Technology Transfer As
Publication of WO2006117526A2 publication Critical patent/WO2006117526A2/en
Publication of WO2006117526A3 publication Critical patent/WO2006117526A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/445—Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/443—Evaluating skin constituents, e.g. elastin, melanin, water

Abstract

A method of estimating the age of a haematoma involves measuring skin reflectance of both normal and bruised skin. A model is provided that relates haemoglobin and bilirubin content with time after injury, and is used to estimate the haemoglobin and bilirubin distributions as a function of depth, for different times after injury. A photon transport model is then used to simulate reflectance spectra corresponding to the estimated haemoglobin and bilirubin distributions at different times after injury. The photon transport model also takes various input parameters calculated from the measured spectra such as melanin content and blood oxygenation. The age of the haematoma is found by comparing the measured and simulated reflectance spectra and determining the time that gives the best fit. Such a method can be implemented using an integrating sphere (2) and a suitably programmed computer (3). The integrating sphere (2) is placed opposite the skin (1) and collects reflectance spectra of both normal and bruised skin. The computer (3) calculates the various parameters required for the photon transport model from the reflectance spectra. The computer (3) also estimates haemoglobin and bilirubin distributions at different times after injury. The computer (3) then simulates reflectance spectra at different times after injury using the photon transport model. Finally, the measured spectrum and simulated spectra are compared in order to estimate the age of the bruise.
PCT/GB2006/001566 2005-04-29 2006-04-28 Determining the age of skin bruises WO2006117526A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0508840A GB0508840D0 (en) 2005-04-29 2005-04-29 Determining the age of skin bruises
GB0508840.6 2005-04-29

Publications (2)

Publication Number Publication Date
WO2006117526A2 WO2006117526A2 (en) 2006-11-09
WO2006117526A3 true WO2006117526A3 (en) 2007-01-18

Family

ID=34674141

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2006/001566 WO2006117526A2 (en) 2005-04-29 2006-04-28 Determining the age of skin bruises

Country Status (2)

Country Link
GB (1) GB0508840D0 (en)
WO (1) WO2006117526A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2443389A (en) * 2006-11-03 2008-05-07 Astron Clinica Ltd Method and apparatus for obtaining a measurement of sun damage
GB2461246A (en) 2008-04-21 2009-12-30 Amc Amsterdam Dating a sample of a body fluid using optical spectroscopy
GB2588200A (en) * 2019-10-15 2021-04-21 Picterus As Method and device for determining the age of a haematoma

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19638839A1 (en) * 1996-09-21 1998-03-26 Univ Schiller Jena Spectrophotometric determination of haematoma originating time for medical applications

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19638839A1 (en) * 1996-09-21 1998-03-26 Univ Schiller Jena Spectrophotometric determination of haematoma originating time for medical applications

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KINCADE KATHY: "Broadband system evaluates age and origin of bruises", LASER FOCUS WORLD; LASER FOCUS WORLD MAY 2004, vol. 40, no. 5, May 2004 (2004-05-01), pages 48 - 53, XP008067947 *

Also Published As

Publication number Publication date
GB0508840D0 (en) 2005-06-08
WO2006117526A2 (en) 2006-11-09

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