WO2006116167A8 - Method for determination of glycoprotein ibalpha (gpibalpha) protein - Google Patents

Method for determination of glycoprotein ibalpha (gpibalpha) protein Download PDF

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Publication number
WO2006116167A8
WO2006116167A8 PCT/US2006/015211 US2006015211W WO2006116167A8 WO 2006116167 A8 WO2006116167 A8 WO 2006116167A8 US 2006015211 W US2006015211 W US 2006015211W WO 2006116167 A8 WO2006116167 A8 WO 2006116167A8
Authority
WO
WIPO (PCT)
Prior art keywords
gpibα
protein
gpibalpha
determination
biological sample
Prior art date
Application number
PCT/US2006/015211
Other languages
French (fr)
Other versions
WO2006116167A9 (en
WO2006116167A1 (en
Inventor
Judy H. Chou
Original Assignee
Wyeth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth filed Critical Wyeth
Priority to CA002603732A priority Critical patent/CA2603732A1/en
Priority to AU2006239939A priority patent/AU2006239939A1/en
Priority to EP06751055A priority patent/EP1877804A1/en
Priority to MX2007012747A priority patent/MX2007012747A/en
Priority to BRPI0609935-1A priority patent/BRPI0609935A2/en
Priority to JP2008507953A priority patent/JP2008538610A/en
Publication of WO2006116167A1 publication Critical patent/WO2006116167A1/en
Publication of WO2006116167A9 publication Critical patent/WO2006116167A9/en
Publication of WO2006116167A8 publication Critical patent/WO2006116167A8/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention provides a novel assay system for detecting the presence, concentration and binding activity of GPIbα in a biological sample. The method for determining the presence of GPIbα in a biological sample comprises: (a) providing a substance comprising GPIbα; (b) contacting the substance from step (a) with a binding protein which binds to GPIbα; (c) adding a detection compound specific to GPIbα; (d) adding a complexing compound that binds the binding protein from step (b); and (e) detecting the detection compound from step (c) wherein a positive detection signal indicates the presence of GPIbα in the biological sample.
PCT/US2006/015211 2005-04-22 2006-04-21 Method for determination of glycoprotein ibalpha (gpibalpha) protein WO2006116167A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA002603732A CA2603732A1 (en) 2005-04-22 2006-04-21 Method for determination of glycoprotein ibalpha (gpibalpha) protein
AU2006239939A AU2006239939A1 (en) 2005-04-22 2006-04-21 Method for determination of glycoprotein ibalpha (GPibalpha) protein
EP06751055A EP1877804A1 (en) 2005-04-22 2006-04-21 Method for determination of glycoprotein ibalpha (gpibalpha) protein
MX2007012747A MX2007012747A (en) 2005-04-22 2006-04-21 Method for determination of glycoprotein ibalpha (gpibalpha) protein.
BRPI0609935-1A BRPI0609935A2 (en) 2005-04-22 2006-04-21 process for the determination of glycoprotein ibalfa protein (gpibalfa)
JP2008507953A JP2008538610A (en) 2005-04-22 2006-04-21 Method for measuring glycoprotein IBα (GPIBα) protein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67392605P 2005-04-22 2005-04-22
US60/673,926 2005-04-22

Publications (3)

Publication Number Publication Date
WO2006116167A1 WO2006116167A1 (en) 2006-11-02
WO2006116167A9 WO2006116167A9 (en) 2007-11-29
WO2006116167A8 true WO2006116167A8 (en) 2010-01-14

Family

ID=36636260

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/015211 WO2006116167A1 (en) 2005-04-22 2006-04-21 Method for determination of glycoprotein ibalpha (gpibalpha) protein

Country Status (8)

Country Link
EP (1) EP1877804A1 (en)
JP (1) JP2008538610A (en)
CN (1) CN101176000A (en)
AU (1) AU2006239939A1 (en)
BR (1) BRPI0609935A2 (en)
CA (1) CA2603732A1 (en)
MX (1) MX2007012747A (en)
WO (1) WO2006116167A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102988983B (en) * 2011-09-09 2014-06-11 苏州苏大赛尔免疫生物技术有限公司 Anti-human platelet membrane glycoprotein Ib alpha chimeric antibody pharmaceutical composition
CN102415478B (en) * 2011-12-12 2014-07-02 北京和利美生物科技有限公司 Ion ligand capable of promoting absorption of trace elements, compound trace element feed additive and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999054360A1 (en) * 1998-04-23 1999-10-28 Ajinomoto Co., Inc. Substance with antithrombotic activity and method for detecting glycokallidin
EP2309275A1 (en) * 1999-07-05 2011-04-13 K.U.Leuven Research & Development Detection of Von-Willebrand factor (vwf) activity

Also Published As

Publication number Publication date
EP1877804A1 (en) 2008-01-16
WO2006116167A9 (en) 2007-11-29
CA2603732A1 (en) 2006-11-02
WO2006116167A1 (en) 2006-11-02
MX2007012747A (en) 2008-01-14
CN101176000A (en) 2008-05-07
BRPI0609935A2 (en) 2010-05-11
JP2008538610A (en) 2008-10-30
AU2006239939A1 (en) 2006-11-02

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