WO2006113599A3 - Methods of diagnosing inflammatory diseases of intestine - Google Patents
Methods of diagnosing inflammatory diseases of intestine Download PDFInfo
- Publication number
- WO2006113599A3 WO2006113599A3 PCT/US2006/014362 US2006014362W WO2006113599A3 WO 2006113599 A3 WO2006113599 A3 WO 2006113599A3 US 2006014362 W US2006014362 W US 2006014362W WO 2006113599 A3 WO2006113599 A3 WO 2006113599A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- intestine
- subclasses
- antigens
- inflammatory diseases
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
Abstract
The present invention provides methods of diagnosing an inflammatory disease of the intestine (IDI) based on detecting altered levels of individual antibody classes and/or subclasses that are specific for Tf-like and/or Tn-like antigens. Additionally, the present invention provides diagnostic methods based on detecting altered levels of two or more antibody classes and/or subclasses that are specific for Tf-like and/or Tn-like antigens. A discriminant function analysis is provided, which reflects the alterations of the levels of two or more antibody classes and/or subclasses that are specific for Tf-like and/or Tn-like antigens. Methods of treating an IDI are also provided.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67174505P | 2005-04-15 | 2005-04-15 | |
US60/671,745 | 2005-04-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006113599A2 WO2006113599A2 (en) | 2006-10-26 |
WO2006113599A3 true WO2006113599A3 (en) | 2006-12-21 |
Family
ID=37054510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/014362 WO2006113599A2 (en) | 2005-04-15 | 2006-04-14 | Methods of diagnosing inflammatory diseases of intestine |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2006113599A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201218341D0 (en) * | 2012-10-12 | 2012-11-28 | Orign Sciences Ltd | Diagnostic method |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010039019A1 (en) * | 1998-12-18 | 2001-11-08 | Antonio Picarelli | Method for the in vitro diagnosis of coeliac disease by secondary antibodies |
US20010046713A1 (en) * | 2000-04-19 | 2001-11-29 | Research Corporation Technologies, Inc. | Diagnostic assay for endometriosis |
WO2005054853A2 (en) * | 2003-12-03 | 2005-06-16 | Glycominds, Ltd | Method for diagnosing diseases based on levels of anti-glycan antibodies |
-
2006
- 2006-04-14 WO PCT/US2006/014362 patent/WO2006113599A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010039019A1 (en) * | 1998-12-18 | 2001-11-08 | Antonio Picarelli | Method for the in vitro diagnosis of coeliac disease by secondary antibodies |
US20010046713A1 (en) * | 2000-04-19 | 2001-11-29 | Research Corporation Technologies, Inc. | Diagnostic assay for endometriosis |
WO2005054853A2 (en) * | 2003-12-03 | 2005-06-16 | Glycominds, Ltd | Method for diagnosing diseases based on levels of anti-glycan antibodies |
Non-Patent Citations (1)
Title |
---|
CAMPBELL BARRY J ET AL: "Altered glycosylation in inflammatory bowel disease: A possible role in cancer development.", GLYCOCONJUGATE JOURNAL, vol. 18, no. 11-12, November 2001 (2001-11-01), pages 851 - 858, XP009073572, ISSN: 0282-0080 * |
Also Published As
Publication number | Publication date |
---|---|
WO2006113599A2 (en) | 2006-10-26 |
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