WO2006113448A1 - Traitement pharmacologique pour le traitement des apnees du sommeil - Google Patents

Traitement pharmacologique pour le traitement des apnees du sommeil Download PDF

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Publication number
WO2006113448A1
WO2006113448A1 PCT/US2006/014099 US2006014099W WO2006113448A1 WO 2006113448 A1 WO2006113448 A1 WO 2006113448A1 US 2006014099 W US2006014099 W US 2006014099W WO 2006113448 A1 WO2006113448 A1 WO 2006113448A1
Authority
WO
WIPO (PCT)
Prior art keywords
sleep
serotonin
ssri
receptor antagonist
apnea
Prior art date
Application number
PCT/US2006/014099
Other languages
English (en)
Inventor
Miodrag Radulovacki
David W. Carley
Original Assignee
The Board Of Trustees Of The University Of Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Board Of Trustees Of The University Of Illinois filed Critical The Board Of Trustees Of The University Of Illinois
Priority to AU2006236602A priority Critical patent/AU2006236602B2/en
Priority to CA002603920A priority patent/CA2603920A1/fr
Priority to EP06740950A priority patent/EP1868602A1/fr
Publication of WO2006113448A1 publication Critical patent/WO2006113448A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne, généralement, des méthodes pharmacologiques destinées à la prévention ou à l'amélioration des troubles respiratoires liés au sommeil par administration d'agents ou de mélanges d'agents qui possèdent une activité pharmacologique liée à la sérotonine.
PCT/US2006/014099 2005-04-15 2006-04-14 Traitement pharmacologique pour le traitement des apnees du sommeil WO2006113448A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2006236602A AU2006236602B2 (en) 2005-04-15 2006-04-14 Pharmacological treatment for sleep apnea
CA002603920A CA2603920A1 (fr) 2005-04-15 2006-04-14 Traitement pharmacologique pour le traitement des apnees du sommeil
EP06740950A EP1868602A1 (fr) 2005-04-15 2006-04-14 Traitement pharmacologique pour le traitement des apnees du sommeil

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67216805P 2005-04-15 2005-04-15
US60/672,168 2005-04-15

Publications (1)

Publication Number Publication Date
WO2006113448A1 true WO2006113448A1 (fr) 2006-10-26

Family

ID=36757052

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/014099 WO2006113448A1 (fr) 2005-04-15 2006-04-14 Traitement pharmacologique pour le traitement des apnees du sommeil

Country Status (4)

Country Link
EP (1) EP1868602A1 (fr)
AU (1) AU2006236602B2 (fr)
CA (1) CA2603920A1 (fr)
WO (1) WO2006113448A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11911351B2 (en) 2018-01-30 2024-02-27 Apnimed, Inc. (Delaware) Methods for treating sleep apnea with combinations of atomoxetine and (R)-oxybutynin

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040013741A1 (en) * 2002-07-15 2004-01-22 Meisel Gerard M. Gastrointestinal compositions
WO2004041272A2 (fr) * 2002-10-31 2004-05-21 The Board Of Trustees Of The University Of Illinois Traitement pharmacologique de l'apnee du sommeil
WO2006069030A1 (fr) * 2004-12-20 2006-06-29 Collegium Pharmaceutical, Inc. Compositions pharmaceutiques destinees a des troubles du sommeil

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040013741A1 (en) * 2002-07-15 2004-01-22 Meisel Gerard M. Gastrointestinal compositions
WO2004041272A2 (fr) * 2002-10-31 2004-05-21 The Board Of Trustees Of The University Of Illinois Traitement pharmacologique de l'apnee du sommeil
WO2006069030A1 (fr) * 2004-12-20 2006-06-29 Collegium Pharmaceutical, Inc. Compositions pharmaceutiques destinees a des troubles du sommeil

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KOPELMAN P G ET AL: "SHORT TERM USE OF FLUOXETINE IN ASYMPTOMATIC OBESE SUBJECTS WITH SLEEP-RELATED HYPOVENTILATION", INTERNATIONAL JOURNAL OF OBESITY, NEWMAN PUBLISHING, LONDON, GB, vol. 16, no. 10, October 1992 (1992-10-01), pages 825 - 830, XP000892935, ISSN: 0307-0565 *
VEASEY S C ET AL: "THE EFFECTS OF ONDANSETRON ON SLEEP-DISORDERED BREATHING IN THE ENGLISH BULLDOG", SLEEP, ALLEN PRESS, LAWRENCE, KS, US, vol. 24, no. 2, 15 March 2001 (2001-03-15), pages 155 - 160, XP001011258, ISSN: 0161-8105 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11911351B2 (en) 2018-01-30 2024-02-27 Apnimed, Inc. (Delaware) Methods for treating sleep apnea with combinations of atomoxetine and (R)-oxybutynin

Also Published As

Publication number Publication date
AU2006236602B2 (en) 2011-10-13
EP1868602A1 (fr) 2007-12-26
AU2006236602A1 (en) 2006-10-26
CA2603920A1 (fr) 2006-10-26

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