WO2006108830A3 - TRANSPLASTOMIC PLANTS EXPRESSING α 1-ANTITRYPSIN - Google Patents

TRANSPLASTOMIC PLANTS EXPRESSING α 1-ANTITRYPSIN Download PDF

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Publication number
WO2006108830A3
WO2006108830A3 PCT/EP2006/061502 EP2006061502W WO2006108830A3 WO 2006108830 A3 WO2006108830 A3 WO 2006108830A3 EP 2006061502 W EP2006061502 W EP 2006061502W WO 2006108830 A3 WO2006108830 A3 WO 2006108830A3
Authority
WO
WIPO (PCT)
Prior art keywords
antitrypsin
plants
plants expressing
relates
present
Prior art date
Application number
PCT/EP2006/061502
Other languages
French (fr)
Other versions
WO2006108830A2 (en
Inventor
Manuel Dubald
Ghislaine Tissot
Marie Nadai
Maxime Vitel
Original Assignee
Bayer Cropscience Sa
Manuel Dubald
Ghislaine Tissot
Marie Nadai
Maxime Vitel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Sa, Manuel Dubald, Ghislaine Tissot, Marie Nadai, Maxime Vitel filed Critical Bayer Cropscience Sa
Publication of WO2006108830A2 publication Critical patent/WO2006108830A2/en
Publication of WO2006108830A3 publication Critical patent/WO2006108830A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8214—Plastid transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

The present invention relates to transplastomic plant cells and plants, wherein the genetic modification leads to the expression in plastids of such plants cells and plants of a recombinant αl -antitrypsin. Furthermore, the present invention relates to methods for the manufacture of such plants and to method for producing αl -antitrypsin from such plants. The present invention also relates to chimeric genes encoding αl -antitrypsin.
PCT/EP2006/061502 2005-04-13 2006-04-11 TRANSPLASTOMIC PLANTS EXPRESSING α 1-ANTITRYPSIN WO2006108830A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP05356065.2 2005-04-13
EP05356065 2005-04-13
US68024405P 2005-05-12 2005-05-12
US60/680,244 2005-05-12

Publications (2)

Publication Number Publication Date
WO2006108830A2 WO2006108830A2 (en) 2006-10-19
WO2006108830A3 true WO2006108830A3 (en) 2006-12-07

Family

ID=36609631

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/061502 WO2006108830A2 (en) 2005-04-13 2006-04-11 TRANSPLASTOMIC PLANTS EXPRESSING α 1-ANTITRYPSIN

Country Status (1)

Country Link
WO (1) WO2006108830A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011076885A1 (en) 2009-12-23 2011-06-30 Bayer Cropscience Ag Plants tolerant to hppd inhibitor herbicides
EA201290560A1 (en) 2009-12-23 2014-05-30 Байер Интеллектуэль Проперти Гмбх PLANTS RESISTANT TO HERBICIDES - HPPD INHIBITORS
WO2011076877A1 (en) 2009-12-23 2011-06-30 Bayer Cropscience Ag Plants tolerant to hppd inhibitor herbicides
EP2516631B1 (en) 2009-12-23 2018-02-14 Bayer Intellectual Property GmbH Plants tolerant to hppd inhibitor herbicides
ES2659085T3 (en) 2009-12-23 2018-03-13 Bayer Intellectual Property Gmbh HPPD Inhibitor Herbicide Tolerant Plants
BR112012019365A2 (en) 2010-02-04 2020-08-25 Bayer Cropscience Ag method to increase the production of biomass, nucleic acid, transgenic plant cell, transgenic plant and transgenic seed
US20130074221A1 (en) * 2010-02-25 2013-03-21 Bioglow, L.L.C. Autoluminescent plants including the bacterial lux operon and methods of making same
BR112013024659A2 (en) 2011-03-25 2018-08-07 Bayer Ip Gmbh use of n- (1,2,5-oxadiazol-3-yl) benzamides to control unwanted plants in transgenic crop areas that are tolerant to hppd inhibitor herbicides
EA201391301A1 (en) 2011-03-25 2014-03-31 Байер Интеллектуэль Проперти Гмбх USE OF N- (tetrazol-4-YL) - or N- (triazol-3-YL) arylcarboxamide or salts thereof for controlling unwanted plants in the growing area of the transgenic crop plants resistant to herbicides HPPD-inhibitors
MA41180A (en) 2014-12-17 2017-10-24 Bayer Cropscience Nv PLANTS CHARACTERIZED BY IMPROVED PHOTOSYNTHETIC CARBON BINDING CAPACITY
WO2019233349A1 (en) 2018-06-04 2019-12-12 青岛清原化合物有限公司 Mutant p-hydroxyphenylpyruvate dioxygenase, and coding nucleic acid and use thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0137633A1 (en) * 1983-08-10 1985-04-17 Zymogenetics, Inc. Method of expressing alpha-1-antitrypsin in bacteria and its use in therapeutic formulations, and vectors and bacteria for such method and their production
WO1998036085A1 (en) * 1997-02-13 1998-08-20 Applied Phytologics, Inc. Production of mature proteins in plants
WO1999038987A1 (en) * 1998-01-30 1999-08-05 Meristem Therapeutics METHOD FOR PRODUCING, BY PLANT CELLS, α1-ANTITRYPSIN AND ITS ALLELES, AND PRODUCTS CONTAINING THE RESULTING α1-ANTITRYPSIN
US20040210966A1 (en) * 2000-02-29 2004-10-21 Henry Daniell Multiple gene expression for engineering novel pathways and hyperexpression of foreign proteins in plants
WO2004099405A1 (en) * 2003-04-11 2004-11-18 Ventria Bioscience Human blood proteins expressed in monocot seeds
WO2005017168A1 (en) * 2003-08-12 2005-02-24 Ventria Bioscience Expression of human milk proteins in transgenic plants

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0137633A1 (en) * 1983-08-10 1985-04-17 Zymogenetics, Inc. Method of expressing alpha-1-antitrypsin in bacteria and its use in therapeutic formulations, and vectors and bacteria for such method and their production
WO1998036085A1 (en) * 1997-02-13 1998-08-20 Applied Phytologics, Inc. Production of mature proteins in plants
WO1999038987A1 (en) * 1998-01-30 1999-08-05 Meristem Therapeutics METHOD FOR PRODUCING, BY PLANT CELLS, α1-ANTITRYPSIN AND ITS ALLELES, AND PRODUCTS CONTAINING THE RESULTING α1-ANTITRYPSIN
US20040210966A1 (en) * 2000-02-29 2004-10-21 Henry Daniell Multiple gene expression for engineering novel pathways and hyperexpression of foreign proteins in plants
WO2004099405A1 (en) * 2003-04-11 2004-11-18 Ventria Bioscience Human blood proteins expressed in monocot seeds
WO2005017168A1 (en) * 2003-08-12 2005-02-24 Ventria Bioscience Expression of human milk proteins in transgenic plants

Also Published As

Publication number Publication date
WO2006108830A2 (en) 2006-10-19

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