WO2006098624A3 - Anti-viral use of a coumarin agent - Google Patents

Anti-viral use of a coumarin agent Download PDF

Info

Publication number
WO2006098624A3
WO2006098624A3 PCT/NL2006/000147 NL2006000147W WO2006098624A3 WO 2006098624 A3 WO2006098624 A3 WO 2006098624A3 NL 2006000147 W NL2006000147 W NL 2006000147W WO 2006098624 A3 WO2006098624 A3 WO 2006098624A3
Authority
WO
WIPO (PCT)
Prior art keywords
carboxylic acid
acid derivatives
coumarin
agent
dihydropyridine
Prior art date
Application number
PCT/NL2006/000147
Other languages
French (fr)
Other versions
WO2006098624A2 (en
Inventor
Geert Jan Sterk
Bernardus Rademaker
Original Assignee
Rademaker Holding B V
Geert Jan Sterk
Bernardus Rademaker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rademaker Holding B V, Geert Jan Sterk, Bernardus Rademaker filed Critical Rademaker Holding B V
Publication of WO2006098624A2 publication Critical patent/WO2006098624A2/en
Publication of WO2006098624A3 publication Critical patent/WO2006098624A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to the use of 1,4-dihydropyridine-5-carboxylic acid derivatives comprising a coumarine group and pyridine-5-carboxylic acid derivatives 1,4-dihydropyridine-5-carboxylic acid derivatives comprising a coumarine group of the general formula (I) or (II) for the preparation of a drug against the cat virus Feline Infectious Peritonitis Syndrome (caused by FIPV) . The importance of an effective agent against FIPV is great since there is no known effective treatment. The invention also relates to cat food.
PCT/NL2006/000147 2005-03-18 2006-03-20 Anti-viral use of a coumarin agent WO2006098624A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1028569A NL1028569C2 (en) 2005-03-18 2005-03-18 Use of a coumarin group comprising derivatives for the preparation of an antiviral agent, as well as cat food.
NL1028569 2005-03-18

Publications (2)

Publication Number Publication Date
WO2006098624A2 WO2006098624A2 (en) 2006-09-21
WO2006098624A3 true WO2006098624A3 (en) 2007-03-08

Family

ID=36592867

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL2006/000147 WO2006098624A2 (en) 2005-03-18 2006-03-20 Anti-viral use of a coumarin agent

Country Status (2)

Country Link
NL (1) NL1028569C2 (en)
WO (1) WO2006098624A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8258154B2 (en) 2006-07-07 2012-09-04 Kalypsys Inc. Bicyclic heteroaryl inhibitors of PDE4

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001014370A1 (en) * 1999-08-23 2001-03-01 Rephartox 1,4-dihydropyridine-5-carboxylic acid ester derivatives and method for the preparation thereof
WO2006098620A1 (en) * 2005-03-17 2006-09-21 Rademaker Holding B.V. Use of derivatives comprising a coumarin group for the preparation of an antiviral agent, derivatives comprising a coumarin group, a method for the preparation thereof, and pharmaceutical compositions containing them

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001014370A1 (en) * 1999-08-23 2001-03-01 Rephartox 1,4-dihydropyridine-5-carboxylic acid ester derivatives and method for the preparation thereof
WO2006098620A1 (en) * 2005-03-17 2006-09-21 Rademaker Holding B.V. Use of derivatives comprising a coumarin group for the preparation of an antiviral agent, derivatives comprising a coumarin group, a method for the preparation thereof, and pharmaceutical compositions containing them

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BALZARINI JAN ET AL: "Pyridine N-oxide derivatives are inhibitory to the human SARS and feline infectious peritonitis coronavirus in cell culture.", THE JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. MAR 2006, vol. 57, no. 3, March 2006 (2006-03-01), pages 472 - 481, XP008073270, ISSN: 0305-7453 *
WEISS RICHARD C: "Treatment of Feline Infectious Peritonitis With Immunomodulating Agents and Antiviral Drugs: A Review", FELINE PRACTICE, vol. 23, no. 3, 1995, pages 103 - 106, XP008073286, ISSN: 1057-6614 *

Also Published As

Publication number Publication date
WO2006098624A2 (en) 2006-09-21
NL1028569C2 (en) 2006-09-20

Similar Documents

Publication Publication Date Title
WO2006046039A3 (en) Tetracyclic indole derivatives as antiviral agents
EP2041159B8 (en) Macrocyclic compounds as antiviral agents
NO20081071L (en) Macrocyclic inhibitors of hepatitis C virus
WO2008064218A3 (en) Amido anti-viral compounds
WO2002100851A3 (en) Thiophene derivatives as antiviral agents for flavivirus infection
WO2004041201A3 (en) Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases
GB0418045D0 (en) Compounds
WO2005035525A3 (en) 2-amido-4-aryloxy-1-carbonylpyrrolidine derivatives as inhibitors of serine proteases, particularly hcv ns3-ns4a protease
WO2005084192A3 (en) Novel 2’-c-methyl nucleoside derivatives
EP3042660A3 (en) Nucleoside derivatives for treatment of caliciviridae infections, including norovirus infections
WO2005113553A3 (en) Azinyl imidazoazine and azinyl carboxamide
WO2007009721A3 (en) Indoline-substituted pyrazoline derivatives, their preparation and use as medicaments
WO2008002924A3 (en) Quinoxalinyl macrocyclic hepatitis c virus serine protease inhibitors
EA200700202A1 (en) Heteroaryl compounds as betamimetics for the treatment of respiratory tract diseases
WO2010033444A8 (en) Crystalline forms of a 2-thiazolyl- 4-quinolinyl-oxy derivative, a potent hcv inhibitor
WO2007041632A3 (en) Methods and pharmaceutical compositions for the treatment and prevention of hepatitis c infection
RU2009126767A (en) 1-Phenyl-1-thio-d-glucitol derivative
WO2007038425A3 (en) Anti-viral compouinds
WO2005084315A3 (en) Pyranoindole derivatives and the use thereof for the treatment of hepatitis c virus infection or disease
WO2006077024A3 (en) 5-aminoindole derivatives
WO2007035010A3 (en) 5,6-dimethylthieno[2,3-di] pyrimidine derivatives, the preparation method thereof and the pharmaceutical composition comprising the same for anti-virus
EP1655292A4 (en) Preventive or therapeutic composition for viral infectious disease
WO2007080270A3 (en) New cholest-4-en-3-one oxime derivatives, pharmaceutical compositions comprising them, and preparation process
SI1970372T1 (en) Salts of 9-oxoacridine-10-acetic acid with 1-alkylamno-1-desoxy-polyols
WO2003090744A8 (en) Antibacterial compositions comprising metal phthalocyanine analogues

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

NENP Non-entry into the national phase

Ref country code: RU

122 Ep: pct application non-entry in european phase

Ref document number: 06732954

Country of ref document: EP

Kind code of ref document: A2