WO2006092385A3 - Use of xcr1 for diagnosing or monitoring of immune tolerance - Google Patents

Use of xcr1 for diagnosing or monitoring of immune tolerance Download PDF

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Publication number
WO2006092385A3
WO2006092385A3 PCT/EP2006/060285 EP2006060285W WO2006092385A3 WO 2006092385 A3 WO2006092385 A3 WO 2006092385A3 EP 2006060285 W EP2006060285 W EP 2006060285W WO 2006092385 A3 WO2006092385 A3 WO 2006092385A3
Authority
WO
WIPO (PCT)
Prior art keywords
xcr1
measuring
expression level
cell sample
diagnosing
Prior art date
Application number
PCT/EP2006/060285
Other languages
English (en)
French (fr)
Other versions
WO2006092385A2 (en
Inventor
Thilo Oelert
Bernd Arnold
Guenter Haemmerling
Original Assignee
Dkfz Krebsforschungszentrum
Univ Ruprecht Karls Heidelberg
Thilo Oelert
Bernd Arnold
Guenter Haemmerling
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dkfz Krebsforschungszentrum, Univ Ruprecht Karls Heidelberg, Thilo Oelert, Bernd Arnold, Guenter Haemmerling filed Critical Dkfz Krebsforschungszentrum
Priority to US11/884,944 priority Critical patent/US20100087630A1/en
Priority to DE602006014103T priority patent/DE602006014103D1/de
Priority to EP06724890A priority patent/EP1861718B1/en
Priority to AT06724890T priority patent/ATE467130T1/de
Publication of WO2006092385A2 publication Critical patent/WO2006092385A2/en
Publication of WO2006092385A3 publication Critical patent/WO2006092385A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Eye Examination Apparatus (AREA)
PCT/EP2006/060285 2005-03-01 2006-02-27 Use of xcr1 for diagnosing or monitoring of immune tolerance WO2006092385A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US11/884,944 US20100087630A1 (en) 2005-03-01 2006-02-27 Use of XCR1 for Diagnosing or Monitoring of Immune Tolerance
DE602006014103T DE602006014103D1 (de) 2005-03-01 2006-02-27 Verwendung von xcri zur diagnose oder überwachung von immuntoleranz
EP06724890A EP1861718B1 (en) 2005-03-01 2006-02-27 Use of xcri for diagnosing or monitoring of immune tolerance
AT06724890T ATE467130T1 (de) 2005-03-01 2006-02-27 Verwendung von xcri zur diagnose oder überwachung von immuntoleranz

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05004392.6 2005-03-01
EP05004392A EP1698902A1 (en) 2005-03-01 2005-03-01 Use of XCR1 for diagnosing or monitoring of immune tolerance

Publications (2)

Publication Number Publication Date
WO2006092385A2 WO2006092385A2 (en) 2006-09-08
WO2006092385A3 true WO2006092385A3 (en) 2007-03-22

Family

ID=34933993

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/060285 WO2006092385A2 (en) 2005-03-01 2006-02-27 Use of xcr1 for diagnosing or monitoring of immune tolerance

Country Status (5)

Country Link
US (1) US20100087630A1 (en10)
EP (2) EP1698902A1 (en10)
AT (1) ATE467130T1 (en10)
DE (1) DE602006014103D1 (en10)
WO (1) WO2006092385A2 (en10)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2062592A1 (en) * 2007-11-20 2009-05-27 BUNDESREPUBLIK DEUTSCHLAND letztvertreten durch das Robert Koch-Institut vertreten durch seinen Präsidenten System for delivery into a XCR1 positive cell and uses thereof
US20120083007A1 (en) * 2010-10-01 2012-04-05 Nadeau Kari C Basophil Activation Based Allergy Diagnostic Test
US9946836B2 (en) 2011-01-31 2018-04-17 Robert Bosch Gmbh Biomarker monitoring device and method
MY166152A (en) * 2011-09-01 2018-06-06 Eisai R&D Man Co Ltd Anti-human xcr1 antibodies
US20130245236A1 (en) * 2012-03-15 2013-09-19 Richard Kroczek Antibodies to the chemokine receptor xcr1

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001072830A2 (de) * 2000-03-31 2001-10-04 Ipf Pharmaceuticals Gmbh Diagnostik- und arzneimittel zur untersuchung des zelloberflächenproteoms von tumor- und entzündungszellen sowie zur behandlung von tumorerkrankungen und entzündlichen erkrankungen vorzugsweise mit hilfe einer spezifischen chemokinrezeptor-analyse und der chemokinrezeptor-ligand-interaktion
WO2002012343A2 (en) * 2000-08-07 2002-02-14 Curagen Corporation Proteins and nucleic acids encoding g-protein coupled receptors
WO2002059608A2 (en) * 2000-11-29 2002-08-01 Lifespan Biosciences, Inc. Compositions and methods related to chemokine (c motif) xc receptor 1 (ccxcr1)
US20030124627A1 (en) * 2001-11-29 2003-07-03 Burmer Glenna C. Diagnostic and therapeutic compositions and methods related to chemokine (C motif ) XC receptor 1 (CCXCR1), a G protein-coupled receptor (GPCR)
US20040191255A1 (en) * 2002-11-15 2004-09-30 Lillard James W. Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001072830A2 (de) * 2000-03-31 2001-10-04 Ipf Pharmaceuticals Gmbh Diagnostik- und arzneimittel zur untersuchung des zelloberflächenproteoms von tumor- und entzündungszellen sowie zur behandlung von tumorerkrankungen und entzündlichen erkrankungen vorzugsweise mit hilfe einer spezifischen chemokinrezeptor-analyse und der chemokinrezeptor-ligand-interaktion
WO2002012343A2 (en) * 2000-08-07 2002-02-14 Curagen Corporation Proteins and nucleic acids encoding g-protein coupled receptors
WO2002059608A2 (en) * 2000-11-29 2002-08-01 Lifespan Biosciences, Inc. Compositions and methods related to chemokine (c motif) xc receptor 1 (ccxcr1)
US20030124627A1 (en) * 2001-11-29 2003-07-03 Burmer Glenna C. Diagnostic and therapeutic compositions and methods related to chemokine (C motif ) XC receptor 1 (CCXCR1), a G protein-coupled receptor (GPCR)
US20040191255A1 (en) * 2002-11-15 2004-09-30 Lillard James W. Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BURST VOLKER R ET AL: "Urinary chemokine (CK) and chemokine receptor (CKR) expression in renal transplantation", JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, vol. 12, no. Program and Abstract Issue, September 2001 (2001-09-01), & ASN (AMERICAN SOCIETY OF NEPHROLOGY)/ISN (INTERNATIONAL SOCIETY OF NEPHROLOGY) WORLD CONGRESS OF NEP; SAN FRANCISCO, CA, USA; OCTOBER 10-17, 2001, pages 854A, XP008049762, ISSN: 1046-6673 *
HIPKIN R WILLIAM ET AL: "Cloning and pharmacological characterization of CXCR1 and CXCR2 from Macaca fascicularis", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 310, no. 1, 1 July 2004 (2004-07-01), pages 291 - 300, XP002335821, ISSN: 0022-3565 *
MIDDEL PETER ET AL: "Expression of the T-cell chemoattractant chemokine lymphotactin in Crohn's disease", AMERICAN JOURNAL OF PATHOLOGY, vol. 159, no. 5, November 2001 (2001-11-01), pages 1751 - 1761, XP002335820, ISSN: 0002-9440 *

Also Published As

Publication number Publication date
WO2006092385A2 (en) 2006-09-08
DE602006014103D1 (de) 2010-06-17
EP1698902A1 (en) 2006-09-06
EP1861718A2 (en) 2007-12-05
US20100087630A1 (en) 2010-04-08
EP1861718B1 (en) 2010-05-05
ATE467130T1 (de) 2010-05-15

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