WO2006087147A3 - Derivatives of aryl (or heteroaryl) azolylcarbinols for the treatment of fibromyalgia - Google Patents

Derivatives of aryl (or heteroaryl) azolylcarbinols for the treatment of fibromyalgia Download PDF

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Publication number
WO2006087147A3
WO2006087147A3 PCT/EP2006/001239 EP2006001239W WO2006087147A3 WO 2006087147 A3 WO2006087147 A3 WO 2006087147A3 EP 2006001239 W EP2006001239 W EP 2006001239W WO 2006087147 A3 WO2006087147 A3 WO 2006087147A3
Authority
WO
WIPO (PCT)
Prior art keywords
fibromyalgia
azolylcarbinols
heteroaryl
aryl
derivatives
Prior art date
Application number
PCT/EP2006/001239
Other languages
French (fr)
Other versions
WO2006087147A2 (en
Inventor
Gomis Antonio Jose Farre
Original Assignee
Esteve Labor Dr
Gomis Antonio Jose Farre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP05003116A external-priority patent/EP1690537A1/en
Priority claimed from EP05004328A external-priority patent/EP1695704A1/en
Priority claimed from ES200500793A external-priority patent/ES2286920B1/en
Application filed by Esteve Labor Dr, Gomis Antonio Jose Farre filed Critical Esteve Labor Dr
Publication of WO2006087147A2 publication Critical patent/WO2006087147A2/en
Publication of WO2006087147A3 publication Critical patent/WO2006087147A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

The present invention refers to the use of derivatives of aryl (or heteroaryl) azolylcarbinols of general formula (I), and their physiologically acceptable salts, as medicinal products for human and/or animal therapeutics for the treatment of the symptoms of fibromyalgia, the prevention or the prophylaxis of the symptoms of fibromyalgia, as well as the prevention or the prophylaxis of the disease causing the symptoms.
PCT/EP2006/001239 2005-02-15 2006-02-10 Derivatives of aryl (or heteroaryl) azolylcarbinols for the treatment of fibromyalgia WO2006087147A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP05003116.0 2005-02-15
EP05003116A EP1690537A1 (en) 2005-02-15 2005-02-15 Derivatives of aryl(or heteroaryl) azolycarbinols for the treatment of fibromyalgia
EP05004328A EP1695704A1 (en) 2005-02-28 2005-02-28 Derivatives of aryl (or heteroaryl) azolylcarbinols for the treatment of fibromyalgia
EP05004328.0 2005-02-28
ES200500793 2005-04-01
ES200500793A ES2286920B1 (en) 2005-02-15 2005-04-01 DERIVATIVES OF ARIL (OR HETEROARIL) AZOLILCARBINOLES FOR THE TREATMENT OF FIBROMIALGIA.

Publications (2)

Publication Number Publication Date
WO2006087147A2 WO2006087147A2 (en) 2006-08-24
WO2006087147A3 true WO2006087147A3 (en) 2006-10-12

Family

ID=36693609

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/001239 WO2006087147A2 (en) 2005-02-15 2006-02-10 Derivatives of aryl (or heteroaryl) azolylcarbinols for the treatment of fibromyalgia

Country Status (1)

Country Link
WO (1) WO2006087147A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007017127A2 (en) * 2005-07-29 2007-02-15 Laboratorios Del Dr. Esteve, S.A Controlled realease dosage form of pirazole compounds to treat urinary incontinence
ES2439255T3 (en) 2007-06-21 2014-01-22 Cara Therapeutics, Inc. Imidazoheterocycles substituted
US8859538B2 (en) 2007-06-21 2014-10-14 Cara Therapeutics, Inc. Uses of substituted imidazoheterocycles

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0289380A1 (en) * 1987-04-10 1988-11-02 Laboratorios Del Dr. Esteve, S.A. Aryl-heteroaryl-carbinol derivatives having an analgesic activity
US6518295B1 (en) * 1998-08-07 2003-02-11 Laboratorios Del Dr. Esteve, S.A. Utilization of aryl(or heteroaryl)azolylcarbinol derivatives in the preparation of a medicament for the treatment of troubles mediated by an excess of substance P
WO2005011684A1 (en) * 2003-07-31 2005-02-10 Grünenthal GmbH Medicaments containing derivatives of aryl (or heteroaryl) azolylcarbinols

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0289380A1 (en) * 1987-04-10 1988-11-02 Laboratorios Del Dr. Esteve, S.A. Aryl-heteroaryl-carbinol derivatives having an analgesic activity
US6518295B1 (en) * 1998-08-07 2003-02-11 Laboratorios Del Dr. Esteve, S.A. Utilization of aryl(or heteroaryl)azolylcarbinol derivatives in the preparation of a medicament for the treatment of troubles mediated by an excess of substance P
WO2005011684A1 (en) * 2003-07-31 2005-02-10 Grünenthal GmbH Medicaments containing derivatives of aryl (or heteroaryl) azolylcarbinols

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
FARRE A J ET AL: "CIZOLIRTINE CITRATE", DRUGS OF THE FUTURE, BARCELONA, ES, vol. 27, no. 8, 1 August 2002 (2002-08-01), pages 721 - 732, XP009043624, ISSN: 0377-8282 *
GOLDENBERG D L: "FIBROMYALGIA, CHRONIC FATIGUE SYNDROME, AND MYOFASCIAL PAIN SYNDROME", CURRENT OPINION IN RHEUMATOLOGY, CURRENT SCIENCE, LONDON, GB, vol. 6, no. 2, 1994, pages 223 - 233, XP001022309, ISSN: 1040-8711 *
KLIMAS N: "Pathogenesis of chronic fatiguesyndrome and fibromyalgia", GROWTH HORMONE AND IGF RESEARCH, CHURCHILL LIVINGSTONE, LONDON,, GB, vol. 8, April 1998 (1998-04-01), pages 123 - 126, XP004849760, ISSN: 1096-6374 *
MONCK N: "CIZOLIRTINE LABORATORIOS DR ESTEVE", CURRENT OPINION IN INVESTIGATIONAL DRUGS, CURRENT DRUGS, LONDON, GB, vol. 2, no. 9, 2001, pages 1269 - 1272, XP009043627, ISSN: 0967-8298 *
SHEMBALKAR P ET AL: "CIZOLIRTINE CITRATE (E-4018) IN THE TREATMENT OF CHRONIC NEUROPATHIC PAIN", CURRENT MEDICAL RESEARCH AND OPINION, HANTS, GB, vol. 17, no. 4, 2001, pages 262 - 266, XP009043626 *

Also Published As

Publication number Publication date
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