WO2006076255A3 - Method of treating or preventing microbial eye infection - Google Patents

Method of treating or preventing microbial eye infection Download PDF

Info

Publication number
WO2006076255A3
WO2006076255A3 PCT/US2006/000593 US2006000593W WO2006076255A3 WO 2006076255 A3 WO2006076255 A3 WO 2006076255A3 US 2006000593 W US2006000593 W US 2006000593W WO 2006076255 A3 WO2006076255 A3 WO 2006076255A3
Authority
WO
WIPO (PCT)
Prior art keywords
treating
infection
eye infection
preventing microbial
eye
Prior art date
Application number
PCT/US2006/000593
Other languages
French (fr)
Other versions
WO2006076255A2 (en
Inventor
Ling Chi Huang
Allan L Goldstein
David Crockford
Jack Finkelstein Jr
Original Assignee
Regenerx Biopharmaceuticals
Ling Chi Huang
Allan L Goldstein
David Crockford
Jack Finkelstein Jr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regenerx Biopharmaceuticals, Ling Chi Huang, Allan L Goldstein, David Crockford, Jack Finkelstein Jr filed Critical Regenerx Biopharmaceuticals
Publication of WO2006076255A2 publication Critical patent/WO2006076255A2/en
Publication of WO2006076255A3 publication Critical patent/WO2006076255A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2292—Thymosin; Related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A method of treatment for treating, preventing, inhibiting or reducing microbial eye infection of eye tissue of a subject, includes administering to a subject in need of such treatment an effective amount of a composition including an antimicrobial agent including amino acid sequence LKKTET or LKKTNT, a conservative variant thereof, or an agent that stimulates production of an LKKTET or LKKTNT peptide, or a conservative variant thereof, in the tissue, so as to inhibit the infection.
PCT/US2006/000593 2005-01-11 2006-01-10 Method of treating or preventing microbial eye infection WO2006076255A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US64252005P 2005-01-11 2005-01-11
US64251605P 2005-01-11 2005-01-11
US60/642,516 2005-01-11
US60/642,520 2005-01-11

Publications (2)

Publication Number Publication Date
WO2006076255A2 WO2006076255A2 (en) 2006-07-20
WO2006076255A3 true WO2006076255A3 (en) 2007-12-13

Family

ID=36678103

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/000593 WO2006076255A2 (en) 2005-01-11 2006-01-10 Method of treating or preventing microbial eye infection

Country Status (1)

Country Link
WO (1) WO2006076255A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011279539A1 (en) * 2010-07-14 2013-03-07 Adistem Ltd Method of treatment of HIV or AIDS

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030040617A9 (en) * 1999-03-12 2003-02-27 Rosen Craig A. Nucleic acids, proteins and antibodies
US20040131626A1 (en) * 2001-03-15 2004-07-08 Goldstein Allan L. Methods of treating disorders of the eye and surrounding tissue with thymosin beta4 (tb4) analogues, isoforms and other derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030040617A9 (en) * 1999-03-12 2003-02-27 Rosen Craig A. Nucleic acids, proteins and antibodies
US20040131626A1 (en) * 2001-03-15 2004-07-08 Goldstein Allan L. Methods of treating disorders of the eye and surrounding tissue with thymosin beta4 (tb4) analogues, isoforms and other derivatives

Also Published As

Publication number Publication date
WO2006076255A2 (en) 2006-07-20

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