WO2006074914A3 - Helicase d'arn humaine et ses utilisations therapeutiques - Google Patents

Helicase d'arn humaine et ses utilisations therapeutiques Download PDF

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Publication number
WO2006074914A3
WO2006074914A3 PCT/EP2006/000190 EP2006000190W WO2006074914A3 WO 2006074914 A3 WO2006074914 A3 WO 2006074914A3 EP 2006000190 W EP2006000190 W EP 2006000190W WO 2006074914 A3 WO2006074914 A3 WO 2006074914A3
Authority
WO
WIPO (PCT)
Prior art keywords
rna helicase
human rna
therapeutic uses
rhau
nucleic acid
Prior art date
Application number
PCT/EP2006/000190
Other languages
English (en)
Other versions
WO2006074914A2 (fr
Inventor
Yoshikuni Nagamine
Hoanh Tran
Original Assignee
Iedrich Miescher Inst For Biom
Yoshikuni Nagamine
Hoanh Tran
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iedrich Miescher Inst For Biom, Yoshikuni Nagamine, Hoanh Tran filed Critical Iedrich Miescher Inst For Biom
Publication of WO2006074914A2 publication Critical patent/WO2006074914A2/fr
Publication of WO2006074914A3 publication Critical patent/WO2006074914A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention concerne des séquences d'acides aminés d'une hélicase d'ARN humaine, RHAU. L'invention concerne plus précisément des molécules d'acides nucléiques et des peptides isolés ainsi que des procédés d'identification de modulateurs de molécules d'acides nucléiques et de peptides RHAU.
PCT/EP2006/000190 2005-01-13 2006-01-11 Helicase d'arn humaine et ses utilisations therapeutiques WO2006074914A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64362105P 2005-01-13 2005-01-13
US60/643,621 2005-01-13

Publications (2)

Publication Number Publication Date
WO2006074914A2 WO2006074914A2 (fr) 2006-07-20
WO2006074914A3 true WO2006074914A3 (fr) 2006-08-31

Family

ID=36586020

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/000190 WO2006074914A2 (fr) 2005-01-13 2006-01-11 Helicase d'arn humaine et ses utilisations therapeutiques

Country Status (1)

Country Link
WO (1) WO2006074914A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110262428A1 (en) * 2008-09-24 2011-10-27 NOVARTIS Forschungsstiftung Zweigniederlassung Fri -edrich Miescher Institute for Biomedical Researc Treating cancer by modulating rna helicases
US20120124682A1 (en) * 2009-05-08 2012-05-17 Janice Lai Dhx36 / rhau knockout mice as experimental models of muscular dystrophy

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001057190A2 (fr) * 2000-02-03 2001-08-09 Hyseq, Inc. Acides nucleiques et polypeptides
WO2002030268A2 (fr) * 2000-10-13 2002-04-18 Eos Biotechnology, Inc. Procedes de diagnostic du cancer de la prostate, compositions et procedes de criblage de modulateurs du cancer de la prostate
WO2005001031A2 (fr) * 2003-05-22 2005-01-06 Isis Pharmaceuticals, Inc. Modulation de la voie d'interference arn

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001057190A2 (fr) * 2000-02-03 2001-08-09 Hyseq, Inc. Acides nucleiques et polypeptides
WO2002030268A2 (fr) * 2000-10-13 2002-04-18 Eos Biotechnology, Inc. Procedes de diagnostic du cancer de la prostate, compositions et procedes de criblage de modulateurs du cancer de la prostate
WO2005001031A2 (fr) * 2003-05-22 2005-01-06 Isis Pharmaceuticals, Inc. Modulation de la voie d'interference arn

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TRAN HOANH ET AL: "Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU.", MOLECULAR CELL. 16 JAN 2004, vol. 13, no. 1, 16 January 2004 (2004-01-16), pages 101 - 111, XP002386855, ISSN: 1097-2765 *

Also Published As

Publication number Publication date
WO2006074914A2 (fr) 2006-07-20

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