WO2006074202A3 - Synthesis of hybrid block copolymers and uses thereof - Google Patents

Synthesis of hybrid block copolymers and uses thereof Download PDF

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Publication number
WO2006074202A3
WO2006074202A3 PCT/US2006/000144 US2006000144W WO2006074202A3 WO 2006074202 A3 WO2006074202 A3 WO 2006074202A3 US 2006000144 W US2006000144 W US 2006000144W WO 2006074202 A3 WO2006074202 A3 WO 2006074202A3
Authority
WO
WIPO (PCT)
Prior art keywords
synthesis
block copolymers
hybrid block
hybrid
preparing
Prior art date
Application number
PCT/US2006/000144
Other languages
French (fr)
Other versions
WO2006074202A2 (en
Inventor
Kurt Breitenkamp
Kevin N Sill
Original Assignee
Intezyne Technologies Inc
Kurt Breitenkamp
Kevin N Sill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intezyne Technologies Inc, Kurt Breitenkamp, Kevin N Sill filed Critical Intezyne Technologies Inc
Priority to NZ556290A priority Critical patent/NZ556290A/en
Priority to JP2007549714A priority patent/JP5086099B2/en
Priority to EP06717363A priority patent/EP1833958A4/en
Priority to AU2006204067A priority patent/AU2006204067B2/en
Priority to NZ598887A priority patent/NZ598887A/en
Priority to MX2007008195A priority patent/MX2007008195A/en
Priority to CA2594240A priority patent/CA2594240C/en
Publication of WO2006074202A2 publication Critical patent/WO2006074202A2/en
Priority to IL184384A priority patent/IL184384A/en
Publication of WO2006074202A3 publication Critical patent/WO2006074202A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0233—Polyamines derived from (poly)oxazolines, (poly)oxazines or having pendant acyl groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/06—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F297/00—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/028—Polyamidoamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L51/00—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L51/08—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Polyamides (AREA)
  • Graft Or Block Polymers (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.
PCT/US2006/000144 2005-01-04 2006-01-04 Synthesis of hybrid block copolymers and uses thereof WO2006074202A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
NZ556290A NZ556290A (en) 2005-01-04 2006-01-04 Synthesis of hybrid block copolymers and uses thereof
JP2007549714A JP5086099B2 (en) 2005-01-04 2006-01-04 Synthesis of hybrid block copolymers and their use
EP06717363A EP1833958A4 (en) 2005-01-04 2006-01-04 Synthesis of hybrid block copolymers and uses thereof
AU2006204067A AU2006204067B2 (en) 2005-01-04 2006-01-04 Synthesis of hybrid block copolymers and uses thereof
NZ598887A NZ598887A (en) 2005-01-04 2006-01-04 A method for preparing a multi-block copolymer
MX2007008195A MX2007008195A (en) 2005-01-04 2006-01-04 Synthesis of hybrid block copolymers and uses thereof.
CA2594240A CA2594240C (en) 2005-01-04 2006-01-04 Synthesis of hybrid block copolymers and uses thereof
IL184384A IL184384A (en) 2005-01-04 2007-07-03 Hybrid block copolymers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64117005P 2005-01-04 2005-01-04
US60/641,170 2005-01-04

Publications (2)

Publication Number Publication Date
WO2006074202A2 WO2006074202A2 (en) 2006-07-13
WO2006074202A3 true WO2006074202A3 (en) 2007-11-22

Family

ID=36648126

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/000144 WO2006074202A2 (en) 2005-01-04 2006-01-04 Synthesis of hybrid block copolymers and uses thereof

Country Status (9)

Country Link
US (2) US7601796B2 (en)
EP (3) EP2348096A3 (en)
JP (1) JP5086099B2 (en)
AU (1) AU2006204067B2 (en)
CA (1) CA2594240C (en)
IL (1) IL184384A (en)
MX (1) MX2007008195A (en)
NZ (3) NZ556290A (en)
WO (1) WO2006074202A2 (en)

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NZ556290A (en) * 2005-01-04 2010-11-26 Intezyne Technologies Inc Synthesis of hybrid block copolymers and uses thereof
US20110124840A1 (en) * 2005-02-11 2011-05-26 Kurt Breitenkamp Synthesis of Homopolymers and Block Copolymers
KR101288729B1 (en) * 2005-04-01 2013-07-23 인터자인 테크놀로지스, 인코포레이티드 Polymeric micelles for drug delivery
EP2010477A4 (en) 2006-04-27 2012-05-30 Intezyne Technologies Inc Poly (ethylene glycol) containing chemically disparate endgroups
EP2010475A2 (en) 2006-04-27 2009-01-07 Intezyne Technologies Incorporated Heterofunctional poly(ethylene glycol) containing acid-labile amino protecting groups and uses thereof
US8066824B2 (en) * 2006-07-07 2011-11-29 Intezyne Technologies, Inc. Covalent modification of metal surfaces
US8188046B2 (en) 2006-10-16 2012-05-29 University Of South Florida Amyloid beta peptides and methods of use
WO2008106657A2 (en) * 2007-03-01 2008-09-04 Intezyne Technologies, Inc. Encapsulated amyloid-beta peptides
US8258190B2 (en) * 2007-04-30 2012-09-04 Intezyne Technologies, Inc. Encapsulated contrast agents
AU2008245404B2 (en) * 2007-04-30 2013-12-05 Intezyne Technologies, Inc. Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents
US20090047517A1 (en) * 2007-06-27 2009-02-19 Francesco Caruso Multilayer polymer films
WO2009134984A1 (en) 2008-04-30 2009-11-05 Intezyne Technolgies Inc. Synthesis of hybrid block copolymers from difluoroacetate ammonium salts
WO2010127154A1 (en) * 2009-04-30 2010-11-04 Intezyne Technologies, Incorporated Polymers for polynucleotide encapsulation
US8524784B2 (en) * 2009-04-30 2013-09-03 Intezyne Technologies, Incorporated Polymer micelles containing anthracylines for the treatment of cancer
EP2424359A4 (en) 2009-04-30 2014-01-15 Intezyne Technologies Inc Polymer micelles containing anthracylines for the treatment of cancer
JP2013507504A (en) 2009-10-16 2013-03-04 ビーエイエスエフ・ソシエタス・エウロパエア Block copolymers as thermoplastic elastomers composed of polyisobutene blocks and oligoamides
US20110256227A1 (en) * 2010-04-14 2011-10-20 Intezyne Technologies, Inc. Controlled polyplex assembly
US8609146B2 (en) 2011-09-19 2013-12-17 Intezyne Technologies, Inc. Multi-block copolymers for the preparation of stabilized micelles
JP5927338B2 (en) 2012-04-11 2016-06-01 インテザイン テクノロジーズ， インコーポレイテッド Block copolymer for stable micelles
US9944752B2 (en) 2012-04-11 2018-04-17 Intezyne Technologies, Inc. Block copolymers for stable micelles
EP3077091A4 (en) * 2013-12-07 2017-12-20 Novomer, Inc. Nanofiltration membranes and methods of use
WO2018148432A1 (en) 2017-02-08 2018-08-16 Intezyne Technologies, Inc. Sn-38 loaded iron crosslinked micelle and methods thereof
CN107840952B (en) * 2017-10-24 2019-05-24 中山大学 A kind of nano vesicle and its preparation method and application of pH and reduction doubling sensitivity
CN113045752A (en) * 2021-03-25 2021-06-29 电子科技大学 Thermo-sensitive polymer, preparation method thereof and thermo-sensitive hydrogel
US11806405B1 (en) 2021-07-19 2023-11-07 Zeno Management, Inc. Immunoconjugates and methods
WO2023014875A2 (en) * 2021-08-04 2023-02-09 Research Foundation Of The City University Of New York Method of synthesizing a mucin and product thereof

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Also Published As

Publication number Publication date
US20110021718A1 (en) 2011-01-27
IL184384A (en) 2013-01-31
EP1833958A4 (en) 2009-01-14
EP2067801A1 (en) 2009-06-10
JP2008527092A (en) 2008-07-24
EP1833958A2 (en) 2007-09-19
AU2006204067A1 (en) 2006-07-13
EP2348096A2 (en) 2011-07-27
JP5086099B2 (en) 2012-11-28
MX2007008195A (en) 2008-02-22
AU2006204067B2 (en) 2011-07-07
US8268936B2 (en) 2012-09-18
CA2594240C (en) 2013-10-15
CA2594240A1 (en) 2006-07-13
US20060172914A1 (en) 2006-08-03
NZ588064A (en) 2012-04-27
NZ556290A (en) 2010-11-26
US7601796B2 (en) 2009-10-13
NZ598887A (en) 2013-06-28
IL184384A0 (en) 2007-10-31
WO2006074202A2 (en) 2006-07-13
EP2348096A3 (en) 2011-11-09

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