WO2006068950A3 - Drug delivery device comprising crosslinked polyurethane-siloxane-containing copolymers - Google Patents

Drug delivery device comprising crosslinked polyurethane-siloxane-containing copolymers Download PDF

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Publication number
WO2006068950A3
WO2006068950A3 PCT/US2005/045646 US2005045646W WO2006068950A3 WO 2006068950 A3 WO2006068950 A3 WO 2006068950A3 US 2005045646 W US2005045646 W US 2005045646W WO 2006068950 A3 WO2006068950 A3 WO 2006068950A3
Authority
WO
WIPO (PCT)
Prior art keywords
siloxane
delivery device
drug delivery
containing copolymers
crosslinked polyurethane
Prior art date
Application number
PCT/US2005/045646
Other languages
French (fr)
Other versions
WO2006068950A2 (en
Inventor
Yu-Chin Lai
Ruiwen Shi
William O Lever Jr
Dominic V Ruscio
Yan Huang
Original Assignee
Bausch & Lomb
Yu-Chin Lai
Ruiwen Shi
William O Lever Jr
Dominic V Ruscio
Yan Huang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch & Lomb, Yu-Chin Lai, Ruiwen Shi, William O Lever Jr, Dominic V Ruscio, Yan Huang filed Critical Bausch & Lomb
Publication of WO2006068950A2 publication Critical patent/WO2006068950A2/en
Publication of WO2006068950A3 publication Critical patent/WO2006068950A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants

Abstract

A drug delivery device for placement in the eye includes a drug core comprising a hydrophobic pharmaceutically active agent, and a holder that holds the drug core. The holder is made of a material impermeable to passage of the active agent and includes an opening for passage of the pharmaceutically agent therethrough to eye tissue. The device includes polyurethane-siloxane- containing copolymers crosslinked with hydrophilic monomers.
PCT/US2005/045646 2004-12-22 2005-12-19 Drug delivery device comprising crosslinked polyurethane-siloxane-containing copolymers WO2006068950A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63848004P 2004-12-22 2004-12-22
US60/638,480 2004-12-22

Publications (2)

Publication Number Publication Date
WO2006068950A2 WO2006068950A2 (en) 2006-06-29
WO2006068950A3 true WO2006068950A3 (en) 2007-02-15

Family

ID=36602228

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/045646 WO2006068950A2 (en) 2004-12-22 2005-12-19 Drug delivery device comprising crosslinked polyurethane-siloxane-containing copolymers

Country Status (1)

Country Link
WO (1) WO2006068950A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002053130A2 (en) * 2001-01-03 2002-07-11 Bausch & Lomb Incorporated Sustained release drug delivery devices with coated drug cores
WO2003040200A1 (en) * 2001-11-02 2003-05-15 Bausch & Lomb Incorporated High refractive index aromatic-based prepolymers

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002053130A2 (en) * 2001-01-03 2002-07-11 Bausch & Lomb Incorporated Sustained release drug delivery devices with coated drug cores
WO2003040200A1 (en) * 2001-11-02 2003-05-15 Bausch & Lomb Incorporated High refractive index aromatic-based prepolymers

Also Published As

Publication number Publication date
WO2006068950A2 (en) 2006-06-29

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