WO2006066268A3 - Synthetic transcription regulators - Google Patents

Synthetic transcription regulators Download PDF

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Publication number
WO2006066268A3
WO2006066268A3 PCT/US2005/046351 US2005046351W WO2006066268A3 WO 2006066268 A3 WO2006066268 A3 WO 2006066268A3 US 2005046351 W US2005046351 W US 2005046351W WO 2006066268 A3 WO2006066268 A3 WO 2006066268A3
Authority
WO
WIPO (PCT)
Prior art keywords
synthetic transcription
transcription regulators
methods
transcription
compositions
Prior art date
Application number
PCT/US2005/046351
Other languages
French (fr)
Other versions
WO2006066268A2 (en
Inventor
Thomas E Wagner
Xianxhang Yu
Original Assignee
Thomas E Wagner
Xianxhang Yu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas E Wagner, Xianxhang Yu filed Critical Thomas E Wagner
Publication of WO2006066268A2 publication Critical patent/WO2006066268A2/en
Publication of WO2006066268A3 publication Critical patent/WO2006066268A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

This invention relates to the regulation of transcription with novel compositions and methods. Compositions and methods providing for the re-addressing of target genes in order to regulate transcription are described.
PCT/US2005/046351 2004-12-17 2005-12-19 Synthetic transcription regulators WO2006066268A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63661204P 2004-12-17 2004-12-17
US60/636,612 2004-12-17

Publications (2)

Publication Number Publication Date
WO2006066268A2 WO2006066268A2 (en) 2006-06-22
WO2006066268A3 true WO2006066268A3 (en) 2007-02-01

Family

ID=36588669

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/046351 WO2006066268A2 (en) 2004-12-17 2005-12-19 Synthetic transcription regulators

Country Status (1)

Country Link
WO (1) WO2006066268A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6015709A (en) * 1997-08-26 2000-01-18 Ariad Pharmaceuticals, Inc. Transcriptional activators, and compositions and uses related thereto
US20030105045A1 (en) * 2000-10-13 2003-06-05 Crosslink Genetics Corporation Artificial transcriptional factors and methods of use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6015709A (en) * 1997-08-26 2000-01-18 Ariad Pharmaceuticals, Inc. Transcriptional activators, and compositions and uses related thereto
US20030105045A1 (en) * 2000-10-13 2003-06-05 Crosslink Genetics Corporation Artificial transcriptional factors and methods of use

Also Published As

Publication number Publication date
WO2006066268A2 (en) 2006-06-22

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