WO2006066083A3 - Apport de medicament corneen renforce par peptides - Google Patents

Apport de medicament corneen renforce par peptides Download PDF

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Publication number
WO2006066083A3
WO2006066083A3 PCT/US2005/045595 US2005045595W WO2006066083A3 WO 2006066083 A3 WO2006066083 A3 WO 2006066083A3 US 2005045595 W US2005045595 W US 2005045595W WO 2006066083 A3 WO2006066083 A3 WO 2006066083A3
Authority
WO
WIPO (PCT)
Prior art keywords
peptide
drug delivery
drug
corneal drug
enhanced corneal
Prior art date
Application number
PCT/US2005/045595
Other languages
English (en)
Other versions
WO2006066083A2 (fr
Inventor
John Tomich
Iwamoto Takeo
Henry Edelhauser
Bernard Mccarey
Original Assignee
Nacelle Therapeutics Inc
John Tomich
Iwamoto Takeo
Henry Edelhauser
Bernard Mccarey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nacelle Therapeutics Inc, John Tomich, Iwamoto Takeo, Henry Edelhauser, Bernard Mccarey filed Critical Nacelle Therapeutics Inc
Priority claimed from US11/304,929 external-priority patent/US7592341B2/en
Publication of WO2006066083A2 publication Critical patent/WO2006066083A2/fr
Publication of WO2006066083A3 publication Critical patent/WO2006066083A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne des techniques et des préparations améliorées destinées à une administration oculaire de médicaments thérapeutiques. Ces préparations comprennent des quantités respectives de médicament et un peptide qui renforce le transport du médicament à travers les tissus oculaires. Ce médicament et ces éléments peptidiques peuvent être administrés séparément ou utilisés sous forme d'un mélange. Le peptide préféré est NC-1059 (Seq. ID No. 1).
PCT/US2005/045595 2004-12-15 2005-12-15 Apport de medicament corneen renforce par peptides WO2006066083A2 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US63643704P 2004-12-15 2004-12-15
US60/636,437 2004-12-15
US75018405P 2005-12-14 2005-12-14
US60/750.184 2005-12-14
US11/304,929 US7592341B2 (en) 2004-12-15 2005-12-15 Peptide-enhanced corneal drug delivery
US11/304,929 2005-12-15

Publications (2)

Publication Number Publication Date
WO2006066083A2 WO2006066083A2 (fr) 2006-06-22
WO2006066083A3 true WO2006066083A3 (fr) 2006-12-21

Family

ID=36588592

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/045595 WO2006066083A2 (fr) 2004-12-15 2005-12-15 Apport de medicament corneen renforce par peptides

Country Status (1)

Country Link
WO (1) WO2006066083A2 (fr)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BROUGHMAN J.R. ET AL.: "Channel-forming peptide modulates transepithelial electrical conductance and solute permeability", AM. J. PHYSIOL. CELL PHYSIOL., vol. 286, no. 6, 2004, pages C-1312 - C-1323, XP003004968 *

Also Published As

Publication number Publication date
WO2006066083A2 (fr) 2006-06-22

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