WO2006064269A3 - Salts of leukotriene antagonist montelukast - Google Patents

Salts of leukotriene antagonist montelukast Download PDF

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Publication number
WO2006064269A3
WO2006064269A3 PCT/GB2005/004896 GB2005004896W WO2006064269A3 WO 2006064269 A3 WO2006064269 A3 WO 2006064269A3 GB 2005004896 W GB2005004896 W GB 2005004896W WO 2006064269 A3 WO2006064269 A3 WO 2006064269A3
Authority
WO
WIPO (PCT)
Prior art keywords
salts
montelukast
leukotriene antagonist
antagonist montelukast
alkaline earth
Prior art date
Application number
PCT/GB2005/004896
Other languages
French (fr)
Other versions
WO2006064269A2 (en
Inventor
Pathi L Srinivas
Dharmaraj Ramachandra Rao
Rajendra Narayanrao Kankan
Jayamadhava P Relekar
Original Assignee
Cipla Ltd
Wain Christopher Paul
Pathi L Srinivas
Dharmaraj Ramachandra Rao
Rajendra Narayanrao Kankan
Jayamadhava P Relekar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd, Wain Christopher Paul, Pathi L Srinivas, Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan, Jayamadhava P Relekar filed Critical Cipla Ltd
Publication of WO2006064269A2 publication Critical patent/WO2006064269A2/en
Publication of WO2006064269A3 publication Critical patent/WO2006064269A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

An alkaline earth metal salt of montelukast, and processes for preparing alkali or alkaline earth metal salts of montelukast (represented by Formula I).
PCT/GB2005/004896 2004-12-17 2005-12-16 Salts of leukotriene antagonist montelukast WO2006064269A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1357MU2004 2004-12-17
IN1357/MUM/2004 2004-12-17

Publications (2)

Publication Number Publication Date
WO2006064269A2 WO2006064269A2 (en) 2006-06-22
WO2006064269A3 true WO2006064269A3 (en) 2006-09-28

Family

ID=36010571

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2005/004896 WO2006064269A2 (en) 2004-12-17 2005-12-16 Salts of leukotriene antagonist montelukast

Country Status (1)

Country Link
WO (1) WO2006064269A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101213177A (en) 2005-07-05 2008-07-02 特瓦制药工业有限公司 Purification of montelukast
IL181607A0 (en) * 2006-02-27 2007-07-04 Chemagis Ltd Novel process for preparing montelukast and salts thereof
US20090281323A1 (en) * 2006-04-12 2009-11-12 Glade Organics Private Limited Process for the manufacture of montelukast sodium
EP1886997A1 (en) * 2006-08-09 2008-02-13 Esteve Quimica, S.A. Process for the purification of montelukast
KR101072896B1 (en) * 2007-10-09 2011-10-17 한미홀딩스 주식회사 Method for preparation of montelukast acid in ionic liquid medium
KR101123292B1 (en) 2008-09-26 2012-03-19 주식회사 엘지생명과학 Process for Preparation of Montelukast Sodium Salt
EP2287154A1 (en) 2009-07-14 2011-02-23 KRKA, D.D., Novo Mesto Efficient synthesis for the preparation of montelukast
WO2011121091A1 (en) 2010-03-31 2011-10-06 Krka, D.D., Novo Mesto Efficient synthesis for the preparation of montelukast and novel crystalline form of intermediates therein

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003066598A1 (en) * 2002-02-07 2003-08-14 Dr. Reddy's Laboratories Ltd. Novel anhydrous amorphous forms of montelukast sodium salt
WO2005040123A1 (en) * 2003-10-10 2005-05-06 Synhton B. V. Solid-state montelukast
WO2005074935A1 (en) * 2004-01-30 2005-08-18 Teva Pharmaceutical Industries Ltd. Montelukast free acid polymorphs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003066598A1 (en) * 2002-02-07 2003-08-14 Dr. Reddy's Laboratories Ltd. Novel anhydrous amorphous forms of montelukast sodium salt
WO2005040123A1 (en) * 2003-10-10 2005-05-06 Synhton B. V. Solid-state montelukast
WO2005074935A1 (en) * 2004-01-30 2005-08-18 Teva Pharmaceutical Industries Ltd. Montelukast free acid polymorphs

Also Published As

Publication number Publication date
WO2006064269A2 (en) 2006-06-22

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