WO2006064235A3 - Formulations for production of capsule shells and capsules - Google Patents

Formulations for production of capsule shells and capsules Download PDF

Info

Publication number
WO2006064235A3
WO2006064235A3 PCT/GB2005/004833 GB2005004833W WO2006064235A3 WO 2006064235 A3 WO2006064235 A3 WO 2006064235A3 GB 2005004833 W GB2005004833 W GB 2005004833W WO 2006064235 A3 WO2006064235 A3 WO 2006064235A3
Authority
WO
WIPO (PCT)
Prior art keywords
production
capsules
formulations
capsule shells
capsule
Prior art date
Application number
PCT/GB2005/004833
Other languages
French (fr)
Other versions
WO2006064235A2 (en
Inventor
Linda Ann Green
Ian James Stringer
Original Assignee
Phoqus Pharmaceuticals Ltd
Linda Ann Green
Ian James Stringer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phoqus Pharmaceuticals Ltd, Linda Ann Green, Ian James Stringer filed Critical Phoqus Pharmaceuticals Ltd
Priority to EP05818082A priority Critical patent/EP1843756A2/en
Priority to JP2007546180A priority patent/JP2008523798A/en
Priority to AU2005315376A priority patent/AU2005315376A1/en
Priority to CA002590832A priority patent/CA2590832A1/en
Publication of WO2006064235A2 publication Critical patent/WO2006064235A2/en
Publication of WO2006064235A3 publication Critical patent/WO2006064235A3/en
Priority to GB0711654A priority patent/GB2436036A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/077—Manufacturing capsule shells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
    • B29C41/003—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor characterised by the choice of material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
    • B29C41/02—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • B29C41/08—Coating a former, core or other substrate by spraying or fluidisation, e.g. spraying powder
    • B29C41/10—Coating a former, core or other substrate by spraying or fluidisation, e.g. spraying powder by fluidisation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
    • B29C41/34—Component parts, details or accessories; Auxiliary operations
    • B29C41/42—Removing articles from moulds, cores or other substrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers
    • C08L1/284—Alkyl ethers with hydroxylated hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D101/00—Coating compositions based on cellulose, modified cellulose, or cellulose derivatives
    • C09D101/08—Cellulose derivatives
    • C09D101/26—Cellulose ethers
    • C09D101/28—Alkyl ethers
    • C09D101/284—Alkyl ethers with hydroxylated hydrocarbon radicals

Abstract

A powder coating material for the production of capsules by electrostatic powder deposition comprises hydroxypropyl cellulose and stearic acid. Such materials provide a suitably flexible capsule and have improved properties in electrostatic deposition process for capsule production. Other possible components included, for example, vinyl pyrrolidone/vinyl acetate copolymers, aminoalkyl methacrylate polymers, sugar alcohols and opacifier.
PCT/GB2005/004833 2004-12-15 2005-12-14 Formulations for production of capsule shells and capsules WO2006064235A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP05818082A EP1843756A2 (en) 2004-12-15 2005-12-14 Formulations for production of capsule shells and capsules
JP2007546180A JP2008523798A (en) 2004-12-15 2005-12-14 Formulation and capsule for capsule shell manufacture
AU2005315376A AU2005315376A1 (en) 2004-12-15 2005-12-14 Formulations for production of capsule shells and capsules
CA002590832A CA2590832A1 (en) 2004-12-15 2005-12-14 Formulations for production of capsule shells and capsules
GB0711654A GB2436036A (en) 2004-12-15 2007-06-15 Formulations for production of capsule shells and capsules

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0427456A GB0427456D0 (en) 2004-12-15 2004-12-15 Formulation for production of capsule shells and capsules
GB0427456.9 2004-12-15

Publications (2)

Publication Number Publication Date
WO2006064235A2 WO2006064235A2 (en) 2006-06-22
WO2006064235A3 true WO2006064235A3 (en) 2006-09-14

Family

ID=34090085

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2005/004833 WO2006064235A2 (en) 2004-12-15 2005-12-14 Formulations for production of capsule shells and capsules

Country Status (7)

Country Link
EP (1) EP1843756A2 (en)
JP (1) JP2008523798A (en)
AU (1) AU2005315376A1 (en)
CA (1) CA2590832A1 (en)
GB (2) GB0427456D0 (en)
WO (1) WO2006064235A2 (en)
ZA (1) ZA200704530B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100074947A1 (en) * 2008-06-13 2010-03-25 Adrian Brown Pharmaceutical Formulations
EP3209282A4 (en) 2014-10-20 2018-05-23 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
US10350568B2 (en) 2016-05-19 2019-07-16 Jiangsu Lefan Capsule Co., Ltd. Membrane-forming composition, soft and hard capsules prepared based on this composition and the preparation methods

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0754452A2 (en) * 1995-07-20 1997-01-22 Tanabe Seiyaku Co., Ltd. Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract
EP1252887A1 (en) * 2000-01-27 2002-10-30 Tanabe Seiyaku Co., Ltd. Sustained-release preparation and process for producing the same
US6783768B1 (en) * 1996-11-13 2004-08-31 Phoqus Pharmaceuticals Limited Method and apparatus for the coating of substrates for pharmaceutical use
WO2004098573A1 (en) * 2003-05-08 2004-11-18 Natco Pharma Limited An improved and stable pharmaceutical composition containing substituted benzimidazoles and a process for its preparation
WO2005000264A1 (en) * 2003-06-25 2005-01-06 Phoqus Pharmaceuticals Limited Production of capsule shells and capsules

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0754452A2 (en) * 1995-07-20 1997-01-22 Tanabe Seiyaku Co., Ltd. Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract
US6783768B1 (en) * 1996-11-13 2004-08-31 Phoqus Pharmaceuticals Limited Method and apparatus for the coating of substrates for pharmaceutical use
EP1252887A1 (en) * 2000-01-27 2002-10-30 Tanabe Seiyaku Co., Ltd. Sustained-release preparation and process for producing the same
WO2004098573A1 (en) * 2003-05-08 2004-11-18 Natco Pharma Limited An improved and stable pharmaceutical composition containing substituted benzimidazoles and a process for its preparation
WO2005000264A1 (en) * 2003-06-25 2005-01-06 Phoqus Pharmaceuticals Limited Production of capsule shells and capsules

Also Published As

Publication number Publication date
WO2006064235A2 (en) 2006-06-22
GB0711654D0 (en) 2007-07-25
GB0427456D0 (en) 2005-01-19
CA2590832A1 (en) 2006-06-22
ZA200704530B (en) 2008-04-30
JP2008523798A (en) 2008-07-10
AU2005315376A1 (en) 2006-06-22
GB2436036A (en) 2007-09-12
EP1843756A2 (en) 2007-10-17

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