WO2006063329A3 - Protection amelioree contre la tuberculose a mycobacteries - Google Patents

Protection amelioree contre la tuberculose a mycobacteries Download PDF

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Publication number
WO2006063329A3
WO2006063329A3 PCT/US2005/044871 US2005044871W WO2006063329A3 WO 2006063329 A3 WO2006063329 A3 WO 2006063329A3 US 2005044871 W US2005044871 W US 2005044871W WO 2006063329 A3 WO2006063329 A3 WO 2006063329A3
Authority
WO
WIPO (PCT)
Prior art keywords
protection against
mycobacterium tuberculosis
enhanced protection
against mycobacterium
present
Prior art date
Application number
PCT/US2005/044871
Other languages
English (en)
Other versions
WO2006063329A2 (fr
Inventor
Jeffrey K Actor
Marian L Kruzel
Original Assignee
Univ Texas
Jeffrey K Actor
Marian L Kruzel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Jeffrey K Actor, Marian L Kruzel filed Critical Univ Texas
Publication of WO2006063329A2 publication Critical patent/WO2006063329A2/fr
Publication of WO2006063329A3 publication Critical patent/WO2006063329A3/fr
Priority to US11/810,477 priority Critical patent/US20070259007A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention porte sur une nouvelle utilisation de la lactoferrine comme composition adjuvante apte à être utilisée dans des vaccins. En particulier, l'invention concerne l'utilisation de la lactoferrine dans le but d'augmenter l'efficacité du vaccin en provoquant une réponse des lymphocytes T auxiliaires et, par conséquent, une protection contre les attaques d'un pathogène virulent. L'invention se rapporte également à un procédé de fabrication de l'adjuvant et à l'utilisation de ce dernier comme médicament.
PCT/US2005/044871 1999-10-19 2005-12-09 Protection amelioree contre la tuberculose a mycobacteries WO2006063329A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US11/810,477 US20070259007A1 (en) 1999-10-19 2007-06-06 Lactoferrin: an adjuvant for vaccines

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63541404P 2004-12-10 2004-12-10
US60/635,414 2004-12-10

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/810,477 Continuation-In-Part US20070259007A1 (en) 1999-10-19 2007-06-06 Lactoferrin: an adjuvant for vaccines

Publications (2)

Publication Number Publication Date
WO2006063329A2 WO2006063329A2 (fr) 2006-06-15
WO2006063329A3 true WO2006063329A3 (fr) 2007-01-04

Family

ID=36578658

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/044871 WO2006063329A2 (fr) 1999-10-19 2005-12-09 Protection amelioree contre la tuberculose a mycobacteries

Country Status (1)

Country Link
WO (1) WO2006063329A2 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277817B1 (en) * 1990-03-08 2001-08-21 Ferro Dynamics Inc. Human lactoferrin

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277817B1 (en) * 1990-03-08 2001-08-21 Ferro Dynamics Inc. Human lactoferrin

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZIMECKI M. ET AL.: "Systemic or local co-administration of lactoferrin with sensitizing dose of antigen enhances delayed type hypersensitivity in mice", IMMUNOLOGY LETTERS, vol. 74, 2000, pages 183 - 188, XP003005416 *

Also Published As

Publication number Publication date
WO2006063329A2 (fr) 2006-06-15

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