WO2006061406A3 - Peptides antimicrobiens, polypeptides comprenant lesdits peptides, procedes pour les preparer, genes codant pour lesdits peptides, vecteurs, organismes transformes et compositions les contenant - Google Patents

Peptides antimicrobiens, polypeptides comprenant lesdits peptides, procedes pour les preparer, genes codant pour lesdits peptides, vecteurs, organismes transformes et compositions les contenant Download PDF

Info

Publication number
WO2006061406A3
WO2006061406A3 PCT/EP2005/056588 EP2005056588W WO2006061406A3 WO 2006061406 A3 WO2006061406 A3 WO 2006061406A3 EP 2005056588 W EP2005056588 W EP 2005056588W WO 2006061406 A3 WO2006061406 A3 WO 2006061406A3
Authority
WO
WIPO (PCT)
Prior art keywords
same
peptides
polypeptides
methods
vectors
Prior art date
Application number
PCT/EP2005/056588
Other languages
English (en)
Other versions
WO2006061406A2 (fr
Inventor
Bernard Jegou
Charles Pineau
Frederic Bourgeon
Jacques Nicolas
Yves Bastide
Yoann Mescam
Original Assignee
Univ Rennes
Innova Proteomics
Inst Nat Rech Inf Automat
Bernard Jegou
Charles Pineau
Frederic Bourgeon
Jacques Nicolas
Yves Bastide
Yoann Mescam
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rennes, Innova Proteomics, Inst Nat Rech Inf Automat, Bernard Jegou, Charles Pineau, Frederic Bourgeon, Jacques Nicolas, Yves Bastide, Yoann Mescam filed Critical Univ Rennes
Priority to CA002592034A priority Critical patent/CA2592034A1/fr
Priority to EP05815800A priority patent/EP1819814A2/fr
Publication of WO2006061406A2 publication Critical patent/WO2006061406A2/fr
Publication of WO2006061406A3 publication Critical patent/WO2006061406A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne de nouveaux peptides présentant des propriétés antimicrobiennes, des polypeptides comprenant lesdits peptides, des procédés pour les préparer, des polynucléotides codant pour lesdits peptides, des gènes chimères, des vecteurs contenant lesdits polynucléotides ou lesdits gènes chimères et des organismes transformés. Les nouveaux peptides selon l'invention sont les peptides de formule (1): C-x(3,7)-C-x(2,4)-C-x(9,10)-C-x(3,6)-CC dans laquelle: x(3,7), x(2,4), x(9,10) et x(3,6), ne prennent pas en même temps les valeurs formant les séquences peptidiques définies par les cinq formules (1A), (1B), (1C), (1D), et (1E) suivantes : (1A): C-x(2)-x-x(1,5)-C-[RKQET]-x(2,3)-C-x(3)-[EDNL]-x(5,6)-C-x(3,6)-CC (1B): C-x(3)-G-x(2)-C-x(3,4)-C-x(9,10)-C-x(2,5)-KCC (1C): C-x(4)-G-x-C-x(3,4)-C-x(7,8)-[ASG]-[TSNHKL]-C-x(5,6)-CC (1D): C-[LVIF]-[QE]-x(4)-C-x(3,4)-C-x(9,10)-C-Y-x(2)-[KR]-G-x-CC (1E): C-M-x(2)-G-x(2)-CWGPC-x(9)-C-x(6)-CC.
PCT/EP2005/056588 2004-12-09 2005-12-07 Peptides antimicrobiens, polypeptides comprenant lesdits peptides, procedes pour les preparer, genes codant pour lesdits peptides, vecteurs, organismes transformes et compositions les contenant WO2006061406A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002592034A CA2592034A1 (fr) 2004-12-09 2005-12-07 Peptides antimicrobiens, polypeptides comprenant lesdits peptides, procedes pour les preparer, genes codant pour lesdits peptides, vecteurs, organismes transformes et compositionsles contenant
EP05815800A EP1819814A2 (fr) 2004-12-09 2005-12-07 Peptides antimicrobiens, polypeptides comprenant lesdits peptides, procedes pour les preparer, genes codant pour lesdits peptides, vecteurs, organismes transformes et compositions les contenant

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0413150A FR2879203A1 (fr) 2004-12-09 2004-12-09 Peptides antimicrobiens, polypeptides comprenant lesdits peptides, procedes pour les preparer, genes codant pour lesdits peptides, vecteurs, organismes transformes et compositions les contenant
FR0413150 2004-12-09

Publications (2)

Publication Number Publication Date
WO2006061406A2 WO2006061406A2 (fr) 2006-06-15
WO2006061406A3 true WO2006061406A3 (fr) 2006-11-30

Family

ID=34954789

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/056588 WO2006061406A2 (fr) 2004-12-09 2005-12-07 Peptides antimicrobiens, polypeptides comprenant lesdits peptides, procedes pour les preparer, genes codant pour lesdits peptides, vecteurs, organismes transformes et compositions les contenant

Country Status (4)

Country Link
EP (1) EP1819814A2 (fr)
CA (1) CA2592034A1 (fr)
FR (1) FR2879203A1 (fr)
WO (1) WO2006061406A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11932594B1 (en) 2023-10-31 2024-03-19 King Faisal University 8-((2-hydroxy-5-methylphenyl)diazenyl)naphthalene-1,3-disulfonic acid as an antioxidant compound

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999013080A1 (fr) * 1997-09-10 1999-03-18 Zymogenetics, Inc. Defensines beta
WO2000046245A2 (fr) * 1999-02-01 2000-08-10 Schering Aktiengesellschaft Proteines antibiotiques humaines
WO2002004487A2 (fr) * 2000-07-11 2002-01-17 Ipf Pharmaceuticals Gmbh Procede d'extraction et d'utilisation de nouvelles defensines humaines en tant que proteines biologiquement actives pour traiter des infections et autres pathologies

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999013080A1 (fr) * 1997-09-10 1999-03-18 Zymogenetics, Inc. Defensines beta
WO2000046245A2 (fr) * 1999-02-01 2000-08-10 Schering Aktiengesellschaft Proteines antibiotiques humaines
WO2002004487A2 (fr) * 2000-07-11 2002-01-17 Ipf Pharmaceuticals Gmbh Procede d'extraction et d'utilisation de nouvelles defensines humaines en tant que proteines biologiquement actives pour traiter des infections et autres pathologies

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BAUER FINN ET AL: "Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity", PROTEIN SCIENCE, vol. 10, no. 12, December 2001 (2001-12-01), pages 2470 - 2479, XP002379594, ISSN: 0961-8368 *
DATABASE GENESEQ 28 May 2002 (2002-05-28), FORSSMANN W ET AL: "Human beta-defensin hBD-27 peptide fragment", XP002342342, Database accession no. AAM49628 *
DATABASE GENESEQ 28 May 2002 (2002-05-28), FORSSMANN W ET AL: "Human beta-defensin hBD-7 peptide fragment", XP002379596, Database accession no. AAM49578 *

Also Published As

Publication number Publication date
WO2006061406A2 (fr) 2006-06-15
EP1819814A2 (fr) 2007-08-22
CA2592034A1 (fr) 2006-06-15
FR2879203A1 (fr) 2006-06-16

Similar Documents

Publication Publication Date Title
EP2048142A3 (fr) Composé cyclique condensé contenant de l'azote disposant d'un groupe pyrazolyl en tant que groupe substituant et sa composition pharmaceutique
WO2007056362A3 (fr) Analogues de glucagon a solubilite et a stabilite physiologiques ameliorees
BRPI0417830A (pt) métodos para a sìntese de bibliotecas codificadas
PT1927597T (pt) Péptidos antibacterianos
CA2432132A1 (fr) Composes de pyrazole utiles en tant qu'inhibiteurs de la proteine kinase
WO2003029264A3 (fr) Analogues de 2-propynyle adenosine presentant une activite agoniste de a2a et compositions en contenant
WO2006086321A3 (fr) Hexapeptides antimicrobiens
MXPA03006485A (es) Formulacion parenteral que contiene analogos de epotilona.
WO2004080148A3 (fr) Nouveaux acides nucleiques et polypeptides
WO2005100352A8 (fr) Antagonistes cgrp selectionnes, leur procede de production et leur utilisation comme medicaments
WO2002060935A8 (fr) Proteine chimerique comprenant des sequences non toxiques d'exotoxine a de pseudomonas et de piline de type iv
WO2004087073A3 (fr) Traitement d'etats de demyelinisation
WO2006061406A3 (fr) Peptides antimicrobiens, polypeptides comprenant lesdits peptides, procedes pour les preparer, genes codant pour lesdits peptides, vecteurs, organismes transformes et compositions les contenant
WO2006090090A3 (fr) Epitopes de vih et composition pharmaceutique les contenant
WO2004075846A3 (fr) Composes tricycliques a base de pyrazolopurine et compositions pharmaceutiques renfermant ces composes
WO2005011609A3 (fr) Composes tricycliques a base de triazolopurine et compositions pharmaceutiques contenant ces composes
EP1479681A4 (fr) DERIVE IMIDAZO(1,2-a)PYRIDINE
WO2004047724A3 (fr) Composes aryle et heteroaryle a action anti-bacterienne et anti-fongique
WO2002042367A3 (fr) Composes de borate polyedriques amino fluores
WO2006010805A3 (fr) Nouveaux polypeptides pour la mise en evidence in vitro et la prevention des infections a legionella pneumophila
WO2004038026A3 (fr) Compositions, organismes et procedes faisant appel a une nouvelle proteine phosphatase humaine
WO2007066018A3 (fr) Peptides qui peuvent se lier a la proteine nef et leurs applications pharmaceutiques
TW200519126A (en) An antibacterial agent a against propionibacterium acnes
WO2007023509A3 (fr) Peptides amphipatiques cationiques nouvellement conçus et synthetises
AU2001295456A1 (en) Nucleotide sequences which code for the gora gene

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KN KP KR KZ LC LK LR LS LT LU LV LY MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2005815800

Country of ref document: EP

Ref document number: 2592034

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: DE

WWP Wipo information: published in national office

Ref document number: 2005815800

Country of ref document: EP