WO2006060393A3 - Analyse systemique biologique - Google Patents

Analyse systemique biologique Download PDF

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Publication number
WO2006060393A3
WO2006060393A3 PCT/US2005/043134 US2005043134W WO2006060393A3 WO 2006060393 A3 WO2006060393 A3 WO 2006060393A3 US 2005043134 W US2005043134 W US 2005043134W WO 2006060393 A3 WO2006060393 A3 WO 2006060393A3
Authority
WO
WIPO (PCT)
Prior art keywords
subjects
patterns
systems
assessment
discovery
Prior art date
Application number
PCT/US2005/043134
Other languages
English (en)
Other versions
WO2006060393A2 (fr
Inventor
Noubar Afeyan
Aram Adourian
Robert Mcburney
Original Assignee
Bg Medicine Inc
Noubar Afeyan
Aram Adourian
Robert Mcburney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/999,512 external-priority patent/US20060115429A1/en
Application filed by Bg Medicine Inc, Noubar Afeyan, Aram Adourian, Robert Mcburney filed Critical Bg Medicine Inc
Priority to US11/791,400 priority Critical patent/US20100057368A1/en
Priority to CA002588759A priority patent/CA2588759A1/fr
Priority to JP2007543592A priority patent/JP2008522166A/ja
Priority to AU2005311954A priority patent/AU2005311954A1/en
Priority to EP05852420A priority patent/EP1827507A4/fr
Publication of WO2006060393A2 publication Critical patent/WO2006060393A2/fr
Publication of WO2006060393A3 publication Critical patent/WO2006060393A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30—Unsupervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B45/00—ICT specially adapted for bioinformatics-related data visualisation, e.g. displaying of maps or networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/20—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Data Mining & Analysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Evolutionary Computation (AREA)
  • Databases & Information Systems (AREA)
  • Bioethics (AREA)
  • Artificial Intelligence (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Software Systems (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

L'invention concerne des procédés destinés à pratiquer la pharmacologie systémique, la toxicologie systémique et la pathologie systémique en utilisant des modèles tels que les images reflétant l'état biologique de sujets tels que les humains ou les animaux de laboratoire. Les modèles sont générés à partir de données obtenues d'un ou de plusieurs échantillons provenant d'un ou de plusieurs sujets par l'application de certaines techniques de traitement de données et reflètent la biochimie des sujets. Les modèles sont utilisés dans la sélection et la découverte de médicaments, l'estimation de la toxicité et de l'efficacité des médicaments, la segmentation des populations, la découverte de sous-types de maladies utilisés en tant que points terminaux de substitution à des fins d'estimation d'options thérapeutiques et pour le diagnostic et le pronostic de maladies.
PCT/US2005/043134 2004-11-30 2005-11-30 Analyse systemique biologique WO2006060393A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US11/791,400 US20100057368A1 (en) 2004-11-30 2005-11-30 Biological Systems Analysis
CA002588759A CA2588759A1 (fr) 2004-11-30 2005-11-30 Analyse systemique biologique
JP2007543592A JP2008522166A (ja) 2004-11-30 2005-11-30 生物学的システム分析法
AU2005311954A AU2005311954A1 (en) 2004-11-30 2005-11-30 Biological systems analysis
EP05852420A EP1827507A4 (fr) 2004-11-30 2005-11-30 Analyse systemique biologique

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/999,512 2004-11-30
US10/999,512 US20060115429A1 (en) 2004-11-30 2004-11-30 Biological systems analysis
US68626705P 2005-06-01 2005-06-01
US60/686,267 2005-06-01

Publications (2)

Publication Number Publication Date
WO2006060393A2 WO2006060393A2 (fr) 2006-06-08
WO2006060393A3 true WO2006060393A3 (fr) 2006-10-12

Family

ID=36565634

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/043134 WO2006060393A2 (fr) 2004-11-30 2005-11-30 Analyse systemique biologique

Country Status (6)

Country Link
US (1) US20100057368A1 (fr)
EP (1) EP1827507A4 (fr)
JP (1) JP2008522166A (fr)
AU (1) AU2005311954A1 (fr)
CA (1) CA2588759A1 (fr)
WO (1) WO2006060393A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8158374B1 (en) 2006-09-05 2012-04-17 Ridge Diagnostics, Inc. Quantitative diagnostic methods using multiple parameters
US8068994B2 (en) * 2007-07-27 2011-11-29 Wayne State University Method for analyzing biological networks
CN102037355A (zh) * 2008-03-04 2011-04-27 里奇诊断学股份有限公司 基于多重生物标记物板块诊断和监测抑郁症
US8440418B2 (en) 2008-11-18 2013-05-14 Ridge Diagnostics, Inc. Metabolic syndrome and HPA axis biomarkers for major depressive disorder
EP2272044A4 (fr) * 2008-03-12 2011-07-06 Ridge Diagnostics Inc Biomarqueurs d'inflammation pour la surveillance de troubles de dépression
DE102014014071A1 (de) * 2014-09-29 2016-03-31 Trw Automotive Gmbh Fahrzeugbedienelement sowie Verfahren zur nichtinvasiven Messung von Biomolekülen
JP6460766B2 (ja) * 2014-12-11 2019-01-30 富士フイルム株式会社 分子計測タイミング取得方法および装置
US10546019B2 (en) 2015-03-23 2020-01-28 International Business Machines Corporation Simplified visualization and relevancy assessment of biological pathways
WO2017161208A1 (fr) * 2016-03-16 2017-09-21 Juno Therapeutics, Inc. Procédés pour déterminer le dosage d'un agent thérapeutique et traitements associés
US10319574B2 (en) * 2016-08-22 2019-06-11 Highland Innovations Inc. Categorization data manipulation using a matrix-assisted laser desorption/ionization time-of-flight mass spectrometer
US10769817B2 (en) * 2017-08-07 2020-09-08 Samsung Display Co., Ltd. Measures for image testing
WO2022192432A1 (fr) * 2021-03-11 2022-09-15 Modicus Prime Ltd. Application de réseau neuronal d'auto-apprentissage pour la détection d'anomalies de produits biopharmaceutiques

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030133972A1 (en) * 2000-10-11 2003-07-17 Targesome, Inc. Targeted multivalent macromolecules

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6647341B1 (en) * 1999-04-09 2003-11-11 Whitehead Institute For Biomedical Research Methods for classifying samples and ascertaining previously unknown classes
CA2415775A1 (fr) * 2000-07-18 2002-01-24 Correlogic Systems, Inc. Procede de distinction d'etats biologiques sur la base de types caches de donnees biologiques
US6813615B1 (en) * 2000-09-06 2004-11-02 Cellomics, Inc. Method and system for interpreting and validating experimental data with automated reasoning
EP1427850A4 (fr) * 2001-08-16 2006-02-08 Phase 1 Molecular Toxicology I Genes et jeux ordonnes d'echantillons humains pertinents sur le plan toxicologique
US6897875B2 (en) * 2002-01-24 2005-05-24 The Board Of The University Of Nebraska Methods and system for analysis and visualization of multidimensional data

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030133972A1 (en) * 2000-10-11 2003-07-17 Targesome, Inc. Targeted multivalent macromolecules

Also Published As

Publication number Publication date
WO2006060393A2 (fr) 2006-06-08
JP2008522166A (ja) 2008-06-26
US20100057368A1 (en) 2010-03-04
CA2588759A1 (fr) 2006-06-08
AU2005311954A1 (en) 2006-06-08
EP1827507A4 (fr) 2008-06-25
EP1827507A2 (fr) 2007-09-05

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