WO2006044616A3 - Methods and compositions associated with administration of an extract of ganoderma lucidum - Google Patents

Methods and compositions associated with administration of an extract of ganoderma lucidum Download PDF

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Publication number
WO2006044616A3
WO2006044616A3 PCT/US2005/036961 US2005036961W WO2006044616A3 WO 2006044616 A3 WO2006044616 A3 WO 2006044616A3 US 2005036961 W US2005036961 W US 2005036961W WO 2006044616 A3 WO2006044616 A3 WO 2006044616A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell
expression
extract
ganoderma lucidum
induce
Prior art date
Application number
PCT/US2005/036961
Other languages
French (fr)
Other versions
WO2006044616A2 (en
Inventor
Chi-Huey Wong
Hsien-Yeh Hsu
Kuo-Feng Hua
Chun-Hung Lin
Jason Hsu
Shui-Tein Chen
Kuo-I Lin
Wen-Bin Yang
John Yu
Alice Yu
Original Assignee
Academia Sinica
Chi-Huey Wong
Hsien-Yeh Hsu
Kuo-Feng Hua
Chun-Hung Lin
Jason Hsu
Shui-Tein Chen
Kuo-I Lin
Wen-Bin Yang
John Yu
Alice Yu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Academia Sinica, Chi-Huey Wong, Hsien-Yeh Hsu, Kuo-Feng Hua, Chun-Hung Lin, Jason Hsu, Shui-Tein Chen, Kuo-I Lin, Wen-Bin Yang, John Yu, Alice Yu filed Critical Academia Sinica
Priority to EP05810080A priority Critical patent/EP1804584A4/en
Priority to JP2007536927A priority patent/JP2008517100A/en
Publication of WO2006044616A2 publication Critical patent/WO2006044616A2/en
Publication of WO2006044616A3 publication Critical patent/WO2006044616A3/en
Priority to US11/534,204 priority patent/US7687064B2/en
Priority to PCT/US2006/037028 priority patent/WO2007047021A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/074—Ganoderma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

A fucose-containing glycoprotein fraction obtainable from an extract of Ganoderma Lucidum Reishi, compositions comprising the fuconse-containing glycoprotein fraction, a method to mediate immunomodulating events associated with IL-1 gene expression, a method to stimulate the expression of an inflammatory cytokine, a method to modulate protein kinase pathways associated with inflammatory cytokine Interleukin 1, a method to induce a TLR mediated event; a method to modulate differentiation of a mononuclear cell, a method to enhance cytotoxicity of an NK cell against an NK-sensitive tumor cell, a method to activate the expression of cytokines, a method to induce Blimp-1 expression in a mouse splenic B cell or human B cell, human mature splenocytes or dendritic cell, a method to inhibit LPS induced nitric oxide production in macrophages, a method to activate spleen cells proliferation, and a method to modify the proteome of a spleen cell.
PCT/US2005/036961 2001-08-06 2005-10-14 Methods and compositions associated with administration of an extract of ganoderma lucidum WO2006044616A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP05810080A EP1804584A4 (en) 2004-10-14 2005-10-14 Methods and compositions associated with administration of an extract of ganoderma lucidum
JP2007536927A JP2008517100A (en) 2004-10-14 2005-10-14 Methods and compositions related to administration of extracts of Ganoderma Lucidum
US11/534,204 US7687064B2 (en) 2001-08-06 2006-09-21 Methods and compositions associated with administration of an extract of Ganoderma lucidum
PCT/US2006/037028 WO2007047021A1 (en) 2005-10-14 2006-09-21 Methods and compositions associated with administration of an extract of ganoderma lucidum

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61926304P 2004-10-14 2004-10-14
US60/619,263 2004-10-14

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US10/213,257 Continuation-In-Part US7135183B1 (en) 2001-08-06 2002-08-06 Immuno-modulating antitumor activities of Ganoderma lucidum (Reishi) polysaccharides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/534,204 Continuation-In-Part US7687064B2 (en) 2001-08-06 2006-09-21 Methods and compositions associated with administration of an extract of Ganoderma lucidum

Publications (2)

Publication Number Publication Date
WO2006044616A2 WO2006044616A2 (en) 2006-04-27
WO2006044616A3 true WO2006044616A3 (en) 2006-08-24

Family

ID=36203535

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/036961 WO2006044616A2 (en) 2001-08-06 2005-10-14 Methods and compositions associated with administration of an extract of ganoderma lucidum

Country Status (3)

Country Link
EP (1) EP1804584A4 (en)
JP (1) JP2008517100A (en)
WO (1) WO2006044616A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105473149A (en) * 2013-07-26 2016-04-06 中央研究院 Antibody-mediated anti-tumor activity induced by reishi mushroom polysaccharides

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7687064B2 (en) 2001-08-06 2010-03-30 Academia Sinica Methods and compositions associated with administration of an extract of Ganoderma lucidum
US7135183B1 (en) 2001-08-06 2006-11-14 Academia Sinica Immuno-modulating antitumor activities of Ganoderma lucidum (Reishi) polysaccharides
US8906380B2 (en) 2005-10-14 2014-12-09 Academia Sinica Fungal immunostimulatory compositions
JP6026715B2 (en) * 2006-06-08 2016-11-16 株式会社アミノアップ化学 Composition having iNOS expression control action
JP2010504339A (en) * 2006-09-21 2010-02-12 アカデミア シニカ Ganoderma mediated enhancement of human tissue progenitor cell adhesion and differentiation
US7785600B2 (en) 2007-08-30 2010-08-31 Wyntek Corporation Compositions and methods for treating allergies, auto-immune diseases, and improving skin condition by ganoderma lucidum (reishi) polysaccharides
US7947283B2 (en) 2007-08-30 2011-05-24 Wyntek Corporation Compositions and methods for treating psoriasis by Ganoderma lucidum (Reishi) polysaccharides
US20090280062A1 (en) * 2008-04-17 2009-11-12 Chi-Huey Wong Longevity-promoting effects of acetic acid and reishi polysaccharide
CN104975041B (en) * 2014-12-19 2018-01-23 中山大学 A kind of promotion method of the monocyte to macrophage differentiation
JP7317358B2 (en) * 2019-07-16 2023-07-31 日本メナード化粧品株式会社 Hematopoietic stem cell differentiation promoter
WO2023033128A1 (en) * 2021-09-03 2023-03-09 国立大学法人京都大学 Method for producing protein

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5334704A (en) * 1987-04-28 1994-08-02 Meiji Milk Products Co., Ltd. Glycoprotein isolated from ganoderma having immunosuppressive activity
US6464982B1 (en) * 2001-11-02 2002-10-15 Chinese Herbal Usa, Inc. Herbal immune system stimulant
US6613754B1 (en) * 2000-09-22 2003-09-02 National Yang-Ming University Polysaccharide-based extract from ganoderma, pharmaceutical use thereof, and process for preparing the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6372629A (en) * 1986-09-17 1988-04-02 Kyoritsu Yakuhin Kogyo Kk Production of physiologically active extract from ganoderma lucidum karst.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5334704A (en) * 1987-04-28 1994-08-02 Meiji Milk Products Co., Ltd. Glycoprotein isolated from ganoderma having immunosuppressive activity
US6613754B1 (en) * 2000-09-22 2003-09-02 National Yang-Ming University Polysaccharide-based extract from ganoderma, pharmaceutical use thereof, and process for preparing the same
US6464982B1 (en) * 2001-11-02 2002-10-15 Chinese Herbal Usa, Inc. Herbal immune system stimulant

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1804584A4 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105473149A (en) * 2013-07-26 2016-04-06 中央研究院 Antibody-mediated anti-tumor activity induced by reishi mushroom polysaccharides

Also Published As

Publication number Publication date
JP2008517100A (en) 2008-05-22
WO2006044616A2 (en) 2006-04-27
EP1804584A4 (en) 2009-08-05
EP1804584A2 (en) 2007-07-11

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