WO2006042542A3 - Production of tetanus, diphtheria, and pertussis toxins and toxoids using fermentation media containing no components of animal or soy origin - Google Patents
Production of tetanus, diphtheria, and pertussis toxins and toxoids using fermentation media containing no components of animal or soy origin Download PDFInfo
- Publication number
- WO2006042542A3 WO2006042542A3 PCT/DK2005/000636 DK2005000636W WO2006042542A3 WO 2006042542 A3 WO2006042542 A3 WO 2006042542A3 DK 2005000636 W DK2005000636 W DK 2005000636W WO 2006042542 A3 WO2006042542 A3 WO 2006042542A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- animal
- tetanus
- media containing
- toxoids
- diphtheria
- Prior art date
Links
- 239000003053 toxin Substances 0.000 title abstract 2
- 231100000765 toxin Toxicity 0.000 title abstract 2
- 201000005702 Pertussis Diseases 0.000 title 1
- 206010043376 Tetanus Diseases 0.000 title 1
- 206010013023 diphtheria Diseases 0.000 title 1
- 230000004151 fermentation Effects 0.000 title 1
- 238000000855 fermentation Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 108700012359 toxins Proteins 0.000 title 1
- 241000209140 Triticum Species 0.000 abstract 2
- 235000021307 Triticum Nutrition 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000588832 Bordetella pertussis Species 0.000 abstract 1
- 241000193449 Clostridium tetani Species 0.000 abstract 1
- 240000007594 Oryza sativa Species 0.000 abstract 1
- 235000007164 Oryza sativa Nutrition 0.000 abstract 1
- 108010081690 Pertussis Toxin Proteins 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 244000061456 Solanum tuberosum Species 0.000 abstract 1
- 235000002595 Solanum tuberosum Nutrition 0.000 abstract 1
- 108010055044 Tetanus Toxin Proteins 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 235000009566 rice Nutrition 0.000 abstract 1
- 229940118376 tetanus toxin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200401595 | 2004-10-19 | ||
DKPA200401595 | 2004-10-19 | ||
DKPA200500110 | 2005-01-21 | ||
DKPA200500110 | 2005-01-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006042542A2 WO2006042542A2 (en) | 2006-04-27 |
WO2006042542A3 true WO2006042542A3 (en) | 2006-12-07 |
Family
ID=36095798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DK2005/000636 WO2006042542A2 (en) | 2004-10-19 | 2005-10-05 | Production of tetanus, diphtheria, and pertussis toxins and toxoids using fermentation media containing no components of animal or soy origin |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2006042542A2 (en) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0505996D0 (en) * | 2005-03-23 | 2005-04-27 | Glaxosmithkline Biolog Sa | Fermentation process |
DE602006011590D1 (en) | 2005-10-11 | 2010-02-25 | Probiotical Spa | METHOD FOR PRODUCING AN ALLERGIC PROBIOTIC BACTERIAL CULTURE AND CORRESPONDING USE |
KR101220239B1 (en) * | 2008-04-01 | 2013-01-09 | 바이오스펙트럼 주식회사 | Composition for Promoting Stem Cell Proliferation Comprising Vegetable Peptone |
GB2495341B (en) | 2011-11-11 | 2013-09-18 | Novartis Ag | Fermentation methods and their products |
DE102011122891B4 (en) | 2011-11-11 | 2014-12-24 | Novartis Ag | Fermentation medium, which is free of animal components, for the preparation of diphtheria toxoids for use in the vaccination of humans |
DE102011118371B4 (en) | 2011-11-11 | 2014-02-13 | Novartis Ag | Composition suitable for human vaccination, comprising a diphtheria toxoid, and process for its preparation |
EP2592137A1 (en) | 2011-11-11 | 2013-05-15 | Novartis AG | Fermentation media free of animal-derived components for production of diphtheria toxoids suitable for human vaccine use |
WO2014009971A2 (en) | 2012-07-07 | 2014-01-16 | Bharat Biotech International Limited | Non-alcoholic vaccine compositions free from animal- origin and process for preparation thereof |
CN104263687A (en) * | 2014-09-29 | 2015-01-07 | 成都欧林生物科技股份有限公司 | Animal origin free culture medium for bordetella pertussis and culture method of animal origin free culture medium |
KR101723168B1 (en) * | 2015-04-28 | 2017-04-05 | 주식회사 대웅 | Medium Composition for Preparing Botulinum Toxin |
KR101723167B1 (en) | 2015-04-28 | 2017-04-05 | 주식회사 대웅 | Medium Composition for Preparing Botulinum Toxin |
KR101729251B1 (en) | 2015-04-28 | 2017-04-21 | 주식회사 대웅 | Medium Composition for Preparing Botulinum Toxin |
CN106282277A (en) * | 2015-06-12 | 2017-01-04 | 天津康希诺生物技术有限公司 | A kind of culture medium for preparing tetanus toxin and application thereof |
SG11201901394XA (en) | 2016-09-02 | 2019-03-28 | Sanofi Pasteur Inc | Neisseria meningitidis vaccine |
EP3632465A1 (en) | 2018-10-03 | 2020-04-08 | Sanofi Pasteur Inc. | Combined immunization against meningococcal disease and human papillomavirus |
KR102197224B1 (en) * | 2019-03-29 | 2020-12-31 | (주)제테마 | A Composition for Culturing Bacteria |
KR102209159B1 (en) * | 2019-03-29 | 2021-01-29 | (주)제테마 | A Method for Producing a Toxin |
KR102485146B1 (en) * | 2019-04-15 | 2023-01-06 | (주)제테마 | Method for preparing Botulinum Toxin |
KR102447441B1 (en) * | 2019-04-15 | 2022-09-27 | (주)제테마 | A Purification Method of Botulinum Toxin |
TW202136518A (en) * | 2019-12-20 | 2021-10-01 | 瑞士商葛德瑪控股公司 | Method of producing botulinum toxin |
CN112646747B (en) * | 2021-01-08 | 2024-03-15 | 苏州聚微生物科技有限公司 | Clostridium tetani culture medium |
WO2023200704A1 (en) | 2022-04-11 | 2023-10-19 | Sanofi Pasteur Inc. | Protein-saccharide conjugation with sodium cyanoborohydride |
CN117535211B (en) * | 2024-01-09 | 2024-04-16 | 中国医学科学院医学生物学研究所 | Culture medium combination of diphtheria bacillus and preparation method of diphtheria toxoid |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998054296A1 (en) * | 1997-05-28 | 1998-12-03 | Chiron S.P.A. | Culture medium with yeast or soy bean extract as aminoacid source and no protein complexes of animal origin |
WO2001005997A2 (en) * | 1999-07-16 | 2001-01-25 | Massachusetts Institute Of Technology | Method for production of tetanus toxin using media substantially free of animal products |
WO2004083400A2 (en) * | 2003-03-18 | 2004-09-30 | Cascade Biologics, Inc. | Animal product-free cell culture media extracts, supplements and culture media supplement systems |
WO2005056773A1 (en) * | 2003-12-12 | 2005-06-23 | Sanofi Pasteur Limited | Production of diphtheria toxin |
-
2005
- 2005-10-05 WO PCT/DK2005/000636 patent/WO2006042542A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998054296A1 (en) * | 1997-05-28 | 1998-12-03 | Chiron S.P.A. | Culture medium with yeast or soy bean extract as aminoacid source and no protein complexes of animal origin |
WO2001005997A2 (en) * | 1999-07-16 | 2001-01-25 | Massachusetts Institute Of Technology | Method for production of tetanus toxin using media substantially free of animal products |
WO2004083400A2 (en) * | 2003-03-18 | 2004-09-30 | Cascade Biologics, Inc. | Animal product-free cell culture media extracts, supplements and culture media supplement systems |
WO2005056773A1 (en) * | 2003-12-12 | 2005-06-23 | Sanofi Pasteur Limited | Production of diphtheria toxin |
Non-Patent Citations (3)
Title |
---|
"scientific research 2003/2004 / Fluka catalogue", 2003, FLUKA CHEMIE GMBH, XP002377083 * |
LARKIN M: "Vegetarian option for biotech drugs could cut BSE risk", LANCET INFECTIOUS DISEASES, US, vol. 2, no. 12, December 2002 (2002-12-01), pages 715, XP004816264, ISSN: 1473-3099 * |
WHITMER M E ET AL: "DEVELOPMENT OF IMPROVED DEFINED MEDIA FOR CLOSTRIDIUM BOTULINUM SEROTYPES A, B, AND E", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, WASHINGTON,DC, US, vol. 54, no. 3, March 1988 (1988-03-01), pages 753 - 759, XP008040512, ISSN: 0099-2240 * |
Also Published As
Publication number | Publication date |
---|---|
WO2006042542A2 (en) | 2006-04-27 |
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