WO2006037994A3 - Methode - Google Patents
Methode Download PDFInfo
- Publication number
- WO2006037994A3 WO2006037994A3 PCT/GB2005/003814 GB2005003814W WO2006037994A3 WO 2006037994 A3 WO2006037994 A3 WO 2006037994A3 GB 2005003814 W GB2005003814 W GB 2005003814W WO 2006037994 A3 WO2006037994 A3 WO 2006037994A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- erbb receptor
- response
- egfr mutations
- mutations altering
- egfr
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0422158A GB0422158D0 (en) | 2004-10-06 | 2004-10-06 | Method |
GB0422158.6 | 2004-10-06 | ||
GB0508493A GB0508493D0 (en) | 2005-04-27 | 2005-04-27 | Method |
GB0508493.4 | 2005-04-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006037994A2 WO2006037994A2 (fr) | 2006-04-13 |
WO2006037994A3 true WO2006037994A3 (fr) | 2006-06-08 |
Family
ID=35453337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2005/003814 WO2006037994A2 (fr) | 2004-10-06 | 2005-10-04 | Methode |
Country Status (2)
Country | Link |
---|---|
TW (1) | TW200617396A (fr) |
WO (1) | WO2006037994A2 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0506670D0 (en) * | 2005-04-01 | 2005-05-11 | Astrazeneca Ab | Method |
CN106755297A (zh) * | 2016-11-15 | 2017-05-31 | 上海派森诺医学检验所有限公司 | 一组基于arms荧光定量pcr检测egfr基因t790m突变的引物组及其制备方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005094357A2 (fr) * | 2004-03-31 | 2005-10-13 | The General Hospital Corporation | Procede permettant de determiner la reponse d'un cancer a des traitements cibles par le recepteur du facteur de croissance epidermique |
-
2005
- 2005-09-26 TW TW094133265A patent/TW200617396A/zh unknown
- 2005-10-04 WO PCT/GB2005/003814 patent/WO2006037994A2/fr active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005094357A2 (fr) * | 2004-03-31 | 2005-10-13 | The General Hospital Corporation | Procede permettant de determiner la reponse d'un cancer a des traitements cibles par le recepteur du facteur de croissance epidermique |
Non-Patent Citations (12)
Title |
---|
GAZDAR A F ET AL: "Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers?", TRENDS IN MOLECULAR MEDICINE, ELSEVIER CURRENT TRENDS, vol. 10, no. 10, October 2004 (2004-10-01), pages 481 - 486, XP004586557, ISSN: 1471-4914 * |
HUANG SHIU-FENG ET AL: "High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan.", CLINICAL CANCER RESEARCH : AN OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH. 15 DEC 2004, vol. 10, no. 24, 15 December 2004 (2004-12-15), pages 8195 - 8203, XP002369911, ISSN: 1078-0432 * |
KOSAKA TAKAYUKI ET AL: "Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.", CANCER RESEARCH. 15 DEC 2004, vol. 64, no. 24, 15 December 2004 (2004-12-15), pages 8919 - 8923, XP002369912, ISSN: 0008-5472 * |
LYNCH THOMAS J ET AL: "Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib.", THE NEW ENGLAND JOURNAL OF MEDICINE. 20 MAY 2004, vol. 350, no. 21, 20 May 2004 (2004-05-20), pages 2129 - 2139, XP002359960, ISSN: 1533-4406 * |
MARCHETTI ANTONIO ET AL: "EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment.", JOURNAL OF CLINICAL ONCOLOGY : OFFICIAL JOURNAL OF THE AMERICAN SOCIETY OF CLINICAL ONCOLOGY. 1 FEB 2005, vol. 23, no. 4, 1 February 2005 (2005-02-01), pages 857 - 865, XP002369910, ISSN: 0732-183X * |
PAEZ J GUILLERMO ET AL: "EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.", SCIENCE. 4 JUN 2004, vol. 304, no. 5676, 4 June 2004 (2004-06-04), pages 1497 - 1500, XP002359959, ISSN: 1095-9203 * |
PAO W ET AL: "EGF receptor gene mutations are common in lung cancers from never smokers and are associated with sensitivity of tumors to gefitinib and erlotinib", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 101, no. 36, 7 September 2004 (2004-09-07), pages 13306 - 13311, XP002334314, ISSN: 0027-8424 * |
PAO WILLIAM ET AL: "Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain.", PLOS MEDICINE / PUBLIC LIBRARY OF SCIENCE. MAR 2005, vol. 2, no. 3, March 2005 (2005-03-01), pages e73, XP002359961, ISSN: 1549-1676 * |
ROSELL ET AL: "Mutations in the tyrosine kinase domain of the EGFR gene associated with gefitinib response in non-small-cell lung cancer", LUNG CANCER, ELSEVIER, AMSTERDAM, NL, vol. 50, no. 1, October 2005 (2005-10-01), pages 25 - 33, XP005106172, ISSN: 0169-5002 * |
TARON MIGUEL ET AL: "Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas.", CLINICAL CANCER RESEARCH : AN OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH. 15 AUG 2005, vol. 11, no. 16, 15 August 2005 (2005-08-15), pages 5878 - 5885, XP002369908, ISSN: 1078-0432 * |
TOKUMO MASAKI ET AL: "The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancers.", CLINICAL CANCER RESEARCH : AN OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH. 1 FEB 2005, vol. 11, no. 3, 1 February 2005 (2005-02-01), pages 1167 - 1173, XP002369909, ISSN: 1078-0432 * |
TOMIZAWA YOSHIO ET AL: "Clinicopathologic significance of the mutations of the epidermal growth factor receptor gene in patients with non-small cell lung cancer.", CLINICAL CANCER RESEARCH : AN OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH. 1 OCT 2005, vol. 11, no. 19 Pt 1, 1 October 2005 (2005-10-01), pages 6816 - 6822, XP002369907, ISSN: 1078-0432 * |
Also Published As
Publication number | Publication date |
---|---|
WO2006037994A2 (fr) | 2006-04-13 |
TW200617396A (en) | 2006-06-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NL301089I2 (nl) | imlifidase | |
WO2008088854A3 (fr) | Marqueurs génétiques pour la prédiction de sensibilité à une polythérapie | |
WO2005056606A3 (fr) | Proteines optimisees qui ciblent le recepteur du facteur de croissance epidermique | |
WO2007109236A8 (fr) | Empreintes digitales micro-arn pendant une mégacaryocytopoïese | |
WO2004071572A3 (fr) | Marqueurs d'expression genique utilises en vue d'une reaction a des medicaments inhibiteurs de egfr | |
WO2003085095A3 (fr) | Nouveaux genes exprimes | |
WO2004074455A3 (fr) | Variants de la region fc | |
IL176674A0 (en) | Fc region variants | |
EP2479284A3 (fr) | Procédés et réactifs pour le traitement et le diagnostic des troubles vasculaires et la dégénération maculaire liée à l'âge | |
WO2004111273A3 (fr) | Marqueurs d'expression genique utilises en vue d'une reaction a des medicaments inhibiteurs de egfr | |
WO2008151803A3 (fr) | Nouveaux polymorphismes du gène abcb1 associés à une absence de réaction clinique à des médicaments | |
WO2006009765A3 (fr) | Procedes d'identification et d'utilisation de composes adaptes au traitement de cellules cancereuses resistantes aux medicaments | |
WO2006081311A3 (fr) | Compositions et methodes de disruption intracellulaire de vegf et de vegfr-2 a l'aide de recepteurs intracellulaires | |
WO2003013533A3 (fr) | Moyens et procedes ameliorant le traitement du cancer sur la base de mrp1 | |
BRPI0819018A2 (pt) | "métodos para determinar se um paciente possui risco aumentado de desenvolver hipertensão, para determinar se um paciente possui maior probalidade de se beneficiar do tratamento com um antagonista de vegf e kits para determinar se um paciente possui risco aumentado de desenvolver hipertensão e para determinar se um paciente possui maior probabilidade de se beneficiar do tratamento com um antagonista de vegf" | |
WO2009087462A3 (fr) | Récepteur à éphrine de type a | |
WO2006078853A3 (fr) | Proteine d'interaction avec la thioredoxine (txnip) en tant que regulateur de la fonction vasculaire | |
WO2004081043A3 (fr) | Variants de baff et leurs methodes d'utilisation | |
WO2006037994A3 (fr) | Methode | |
WO2005112568A3 (fr) | Marqueurs haplotypes et procedes d'utilisation de ceux-ci pour determiner la reponse a un traitement | |
WO2005007871A3 (fr) | Marqueur genetique de reponse a des antipsychotiques atypiques et a des antidepresseurs et leurs methodes d'utilisation | |
DE602005016290D1 (de) | Glichkeit | |
WO2007131133A3 (fr) | Procédés et compositions se rapportant aux polypeptides zpa | |
WO2003055980A3 (fr) | Molecules du type il-17 et utilisations associees | |
WO2008052016A3 (fr) | Récepteur associé à la sortiline sorl1 présentant un lien fonctionnel et génétique avec la maladie d'alzheimer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV LY MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
DPE1 | Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101) | ||
NENP | Non-entry into the national phase |
Ref country code: DE |
|
122 | Ep: pct application non-entry in european phase |