WO2006023972A3 - cAMP REPORTERS - Google Patents

cAMP REPORTERS Download PDF

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Publication number
WO2006023972A3
WO2006023972A3 PCT/US2005/030099 US2005030099W WO2006023972A3 WO 2006023972 A3 WO2006023972 A3 WO 2006023972A3 US 2005030099 W US2005030099 W US 2005030099W WO 2006023972 A3 WO2006023972 A3 WO 2006023972A3
Authority
WO
WIPO (PCT)
Prior art keywords
camp
reporters
camp reporters
high spatial
temporal resolution
Prior art date
Application number
PCT/US2005/030099
Other languages
French (fr)
Other versions
WO2006023972A2 (en
Inventor
Jin Zhang
Lisa Marie Dipilato
Original Assignee
Univ Johns Hopkins
Jin Zhang
Lisa Marie Dipilato
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins, Jin Zhang, Lisa Marie Dipilato filed Critical Univ Johns Hopkins
Priority to EP05808843A priority Critical patent/EP1791972A4/en
Publication of WO2006023972A2 publication Critical patent/WO2006023972A2/en
Priority to US11/586,707 priority patent/US8236523B2/en
Publication of WO2006023972A3 publication Critical patent/WO2006023972A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

cAMP reporters useful for obtaining measurements of cAMP levels with high spatial and temporal resolution.
PCT/US2005/030099 2004-08-23 2005-08-23 cAMP REPORTERS WO2006023972A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP05808843A EP1791972A4 (en) 2004-08-23 2005-08-23 cAMP REPORTERS
US11/586,707 US8236523B2 (en) 2004-08-23 2006-10-26 Camp reporters and high throughput assays

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60362304P 2004-08-23 2004-08-23
US60/603,623 2004-08-23
US68192305P 2005-05-17 2005-05-17
US60/681,923 2005-05-17

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/586,707 Continuation-In-Part US8236523B2 (en) 2004-08-23 2006-10-26 Camp reporters and high throughput assays

Publications (2)

Publication Number Publication Date
WO2006023972A2 WO2006023972A2 (en) 2006-03-02
WO2006023972A3 true WO2006023972A3 (en) 2009-04-16

Family

ID=35968313

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/030099 WO2006023972A2 (en) 2004-08-23 2005-08-23 cAMP REPORTERS

Country Status (2)

Country Link
EP (1) EP1791972A4 (en)
WO (1) WO2006023972A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2308978B8 (en) 2003-10-10 2015-04-08 Promega Corporation Luciferase biosensor
EP2004813B1 (en) * 2006-04-03 2015-06-03 Promega Corporation Permuted and nonpermuted luciferase biosensors binding cyclic nucleotides
US9045730B2 (en) 2008-05-19 2015-06-02 Promega Corporation Luciferase biosensors for cAMP
WO2010119693A1 (en) * 2009-04-17 2010-10-21 Kobe University Method of screening for insulin secretion-potentiating agents
JP5961163B2 (en) 2010-05-11 2016-08-02 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ Mutant protease biosensor with enhanced detection properties
US9290794B2 (en) 2010-05-11 2016-03-22 Promega Corporation Mutant protease biosensors with enhanced detection characteristics
JP5893241B2 (en) * 2010-08-31 2016-03-23 オリンパス株式会社 Calcium analysis method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6573059B1 (en) * 1999-06-04 2003-06-03 Rmf Dictagene S.A. Use of the regulatory subunit of the camp dependent protein kinase (PKA) from dictyostelium for camp measurements

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1536020A1 (en) * 2003-11-26 2005-06-01 Bayerische Julius-Maximilians-Universität Würzburg Means and methods for optical determination of cAMP in vitro and in vivo

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6573059B1 (en) * 1999-06-04 2003-06-03 Rmf Dictagene S.A. Use of the regulatory subunit of the camp dependent protein kinase (PKA) from dictyostelium for camp measurements

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
NIKOLAEV ET AL.: "Novel single Chain cAMP Sensors for Receptor-induced Signal Propagation.", JBC., vol. 279, no. 36, 3 September 2004 (2004-09-03), pages 37215 - 37218, XP008118423 *
See also references of EP1791972A4 *
VIOLIN J.D. ET AL.: "A Genetically Encoded fluorescent Reporter Reveals Oscillatory Phosphorylation by Protein kinase C.", JCB., vol. 161, no. 5, 9 June 2003 (2003-06-09), pages 899 - 909, XP008118526 *
ZACCOLO ET AL.: "A Genetically Encoded, fluorescent Indicator for Cyclic AMP in Living Cells", NATURE CELL BIOLOGY., vol. 2, no. 1, January 2000 (2000-01-01), pages 25 - 29, XP002251301 *
ZHANG ET AL.: "Genetically Encodeed reporters ofProtein Kinase A activity Reveal Impact of Substrate Tethering.", PNAS. NATURE CELL BIOLOGY., vol. 98, no. 26, 18 December 2001 (2001-12-18), pages 14997 - 15002, XP001161076 *

Also Published As

Publication number Publication date
EP1791972A2 (en) 2007-06-06
EP1791972A4 (en) 2009-12-02
WO2006023972A2 (en) 2006-03-02

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