WO2006008757A3 - Stabilized pharmaceutical compositions of pravastatin - Google Patents

Stabilized pharmaceutical compositions of pravastatin Download PDF

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Publication number
WO2006008757A3
WO2006008757A3 PCT/IN2005/000191 IN2005000191W WO2006008757A3 WO 2006008757 A3 WO2006008757 A3 WO 2006008757A3 IN 2005000191 W IN2005000191 W IN 2005000191W WO 2006008757 A3 WO2006008757 A3 WO 2006008757A3
Authority
WO
WIPO (PCT)
Prior art keywords
pravastatin
pharmaceutical compositions
stabilized pharmaceutical
stabilized
pharmaceutically acceptable
Prior art date
Application number
PCT/IN2005/000191
Other languages
French (fr)
Other versions
WO2006008757A2 (en
Inventor
Jatin Desai
Keyur Patel
Daxesh Patel
Sweety Christian
Original Assignee
Cadila Healthcare Ltd
Jatin Desai
Keyur Patel
Daxesh Patel
Sweety Christian
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Healthcare Ltd, Jatin Desai, Keyur Patel, Daxesh Patel, Sweety Christian filed Critical Cadila Healthcare Ltd
Publication of WO2006008757A2 publication Critical patent/WO2006008757A2/en
Publication of WO2006008757A3 publication Critical patent/WO2006008757A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Abstract

Stabilized pharmaceutical compositions containing Pravastatin or its pharmaceutically acceptable salts are disclosed. The composition comprises of pravastatin or its pharmaceutically acceptable salt, stabilized by synergistic combination of substantially low amount of alkalizing agent and nonionic surfactant, to impart a pH between 8 to 8.75 to an aqueous solution or dispersion of the said composition.
PCT/IN2005/000191 2004-05-05 2005-05-05 Stabilized pharmaceutical compositions of pravastatin WO2006008757A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN518MU2004 2004-05-05
IN518/MUM/2004 2004-05-05

Publications (2)

Publication Number Publication Date
WO2006008757A2 WO2006008757A2 (en) 2006-01-26
WO2006008757A3 true WO2006008757A3 (en) 2006-04-27

Family

ID=35550643

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2005/000191 WO2006008757A2 (en) 2004-05-05 2005-05-05 Stabilized pharmaceutical compositions of pravastatin

Country Status (1)

Country Link
WO (1) WO2006008757A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3060390B1 (en) * 2016-12-19 2020-09-25 Bh Pharma FORMULATION CONSISTING OF PRAVASTATIN AND ACETYLSALYCILIC ACID
CN110840866A (en) * 2018-08-20 2020-02-28 成都新睿泰康科技有限公司 Asarin pharmaceutical composition and application thereof in preventing and treating neurodegenerative diseases

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030447A (en) * 1988-03-31 1991-07-09 E. R. Squibb & Sons, Inc. Pharmaceutical compositions having good stability
WO2000035425A1 (en) * 1998-12-16 2000-06-22 Lek Pharmaceutical And Chemical Company D.D. STABLE PHARMACEUTICAL FORMULATION COMPRISING A HMG-CoA REDUCTASE INHIBITOR
WO2002076376A2 (en) * 2001-03-27 2002-10-03 Ranbaxy Laboratories Limited A stable pharmaceutical composition of pravastatin
WO2003000239A1 (en) * 2001-06-21 2003-01-03 Andrx Pharmaceuticals, Inc. Stable pharmaceutical compositions containing pravastatin
WO2005013940A1 (en) * 2003-08-06 2005-02-17 Galephar M/F Stable controlled release pharmaceutical compositions containing fenofibrate and pravastatin

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030447A (en) * 1988-03-31 1991-07-09 E. R. Squibb & Sons, Inc. Pharmaceutical compositions having good stability
WO2000035425A1 (en) * 1998-12-16 2000-06-22 Lek Pharmaceutical And Chemical Company D.D. STABLE PHARMACEUTICAL FORMULATION COMPRISING A HMG-CoA REDUCTASE INHIBITOR
WO2002076376A2 (en) * 2001-03-27 2002-10-03 Ranbaxy Laboratories Limited A stable pharmaceutical composition of pravastatin
WO2003000239A1 (en) * 2001-06-21 2003-01-03 Andrx Pharmaceuticals, Inc. Stable pharmaceutical compositions containing pravastatin
WO2003000177A2 (en) * 2001-06-21 2003-01-03 Andrx Pharmaceuticals, Inc. Stable controlled release pharmaceutical compositions containing pravastatin
WO2005013940A1 (en) * 2003-08-06 2005-02-17 Galephar M/F Stable controlled release pharmaceutical compositions containing fenofibrate and pravastatin

Also Published As

Publication number Publication date
WO2006008757A2 (en) 2006-01-26

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