WO2006008633A3 - Receptor protein tyrosine phosphatase gamma (ptprg) as marker for dendritic cells cells - Google Patents

Receptor protein tyrosine phosphatase gamma (ptprg) as marker for dendritic cells cells Download PDF

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Publication number
WO2006008633A3
WO2006008633A3 PCT/IB2005/002027 IB2005002027W WO2006008633A3 WO 2006008633 A3 WO2006008633 A3 WO 2006008633A3 IB 2005002027 W IB2005002027 W IB 2005002027W WO 2006008633 A3 WO2006008633 A3 WO 2006008633A3
Authority
WO
WIPO (PCT)
Prior art keywords
ptprg
dendritic cells
cells
tyrosine phosphatase
marker
Prior art date
Application number
PCT/IB2005/002027
Other languages
French (fr)
Other versions
WO2006008633A2 (en
Inventor
Claudio Sorio
Original Assignee
Consorzio Per Gli Studi Uni In
Claudio Sorio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consorzio Per Gli Studi Uni In, Claudio Sorio filed Critical Consorzio Per Gli Studi Uni In
Priority to EP05780140A priority Critical patent/EP1784641A2/en
Priority to US11/572,098 priority patent/US20090131346A1/en
Publication of WO2006008633A2 publication Critical patent/WO2006008633A2/en
Publication of WO2006008633A3 publication Critical patent/WO2006008633A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Method for identifying myeloid or plasmacytoid dendritic cells provided by a mammal, stimulated or unstimulated, comprising the steps of: a) preparing a cell sample; b) contacting the cell sample myeloid or plasmacytoid dendritic cells to form a complex; c) detecting the complex; characterized in that the phosphatase is the Receptor type Tyrosine Phosphatase Gamma Protein (PTPRG), acting as a specific marker of said dendritic cells, and in thaht the compound is a polypeptide capable of selectively bind to the PTPRG or to a fragment thereof or to a oligonucleotide complementary to a PTPRG mRNA logonucleotide in such a manner as to allow the selective recognizing of the dendritic cells in the cell sample.
PCT/IB2005/002027 2004-07-16 2005-07-15 Receptor protein tyrosine phosphatase gamma (ptprg) as marker for dendritic cells cells WO2006008633A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP05780140A EP1784641A2 (en) 2004-07-16 2005-07-15 Receptor protein tyrosine phosphatase gamma (ptprg) as marker for dendritic cells
US11/572,098 US20090131346A1 (en) 2004-07-16 2005-07-15 Antibody and method for identification of dendritic cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITVI2004A000174 2004-07-16
IT000174A ITVI20040174A1 (en) 2004-07-16 2004-07-16 ANTIBODY AND METHOD FOR THE IDENTIFICATION OF DENDRITIC CELLS

Publications (2)

Publication Number Publication Date
WO2006008633A2 WO2006008633A2 (en) 2006-01-26
WO2006008633A3 true WO2006008633A3 (en) 2007-01-25

Family

ID=35785596

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/002027 WO2006008633A2 (en) 2004-07-16 2005-07-15 Receptor protein tyrosine phosphatase gamma (ptprg) as marker for dendritic cells cells

Country Status (4)

Country Link
US (1) US20090131346A1 (en)
EP (1) EP1784641A2 (en)
IT (1) ITVI20040174A1 (en)
WO (1) WO2006008633A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITVI20060029A1 (en) * 2006-01-24 2007-07-25 Consorzio Per Gli Studi Universitari In Verona METHOD FOR DIAGNOSTICS OF MYELOPROLIFERATIVE DISEASES
CA2710196A1 (en) * 2007-12-20 2009-07-09 Celgene Corporation Use of micro-rna as a biomarker of immunomodulatory drug activity
ES2825723T3 (en) * 2009-07-13 2021-05-17 Biogencell Ltd Method of using lead cells for activation and differentiation of specific stem / progenitor cells
US8956870B2 (en) 2012-01-19 2015-02-17 Biogencell, Ltd. Method for using directing cells for specific stem/progenitor cell activation and differentiation
CN114733455B (en) * 2022-04-15 2023-02-14 北京田园奥瑞生物科技有限公司 Method for rapidly parting mammal sperms by utilizing biologically modified beta-cyclodextrin nano magnetic particles

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LIU SULING ET AL: "Function analysis of estrogenically regulated protein tyrosine phosphatase gamma (PTPgamma) in human breast cancer cell line MCF-7.", ONCOGENE, vol. 23, no. 6, 12 February 2004 (2004-02-12), pages 1256 - 1262, XP002378641, ISSN: 0950-9232 *
SORIO CLAUDIO ET AL: "Receptor protein tyrosine phosphatase gamma, Ptp-gamma, regulates hematopoietic differentiation", BLOOD, vol. 90, no. 1, 1997, pages 49 - 57, XP002378640, ISSN: 0006-4971 *

Also Published As

Publication number Publication date
US20090131346A1 (en) 2009-05-21
WO2006008633A2 (en) 2006-01-26
ITVI20040174A1 (en) 2004-10-16
EP1784641A2 (en) 2007-05-16

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