WO2006004778A3 - Implant with a biofunctionalized surface and method for its production - Google Patents

Implant with a biofunctionalized surface and method for its production Download PDF

Info

Publication number
WO2006004778A3
WO2006004778A3 PCT/US2005/022973 US2005022973W WO2006004778A3 WO 2006004778 A3 WO2006004778 A3 WO 2006004778A3 US 2005022973 W US2005022973 W US 2005022973W WO 2006004778 A3 WO2006004778 A3 WO 2006004778A3
Authority
WO
WIPO (PCT)
Prior art keywords
implant
production
method
peptide
biofunctionalized surface
Prior art date
Application number
PCT/US2005/022973
Other languages
French (fr)
Other versions
WO2006004778A2 (en
Inventor
Klaus Becker
Susanne Bierbaum
Worch Hartmut
Dieter Scharnweber
Original Assignee
Klaus Becker
Susanne Bierbaum
Dentsply Int Inc
Worch Hartmut
Dieter Scharnweber
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP04001534 priority Critical
Priority to EP0401534.8 priority
Application filed by Klaus Becker, Susanne Bierbaum, Dentsply Int Inc, Worch Hartmut, Dieter Scharnweber filed Critical Klaus Becker
Publication of WO2006004778A2 publication Critical patent/WO2006004778A2/en
Publication of WO2006004778A3 publication Critical patent/WO2006004778A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/30Inorganic materials
    • A61L27/32Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/25Peptides having up to 20 amino acids in a defined sequence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings

Abstract

A dental implant is described that includes a surface coating of a nanocrystalline apatite layer that is applied electrochemically. A peptide that has an osteoconductive effect is included in an electrolyte solution resulting in a co-deposition with the apatite such that the peptide remains effective in promoting cell adhesion.
PCT/US2005/022973 2004-06-30 2005-06-27 Implant with a biofunctionalized surface and method for its production WO2006004778A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP04001534 2004-06-30
EP0401534.8 2004-06-30

Publications (2)

Publication Number Publication Date
WO2006004778A2 WO2006004778A2 (en) 2006-01-12
WO2006004778A3 true WO2006004778A3 (en) 2006-03-09

Family

ID=35432312

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/022973 WO2006004778A2 (en) 2004-06-30 2005-06-27 Implant with a biofunctionalized surface and method for its production

Country Status (1)

Country Link
WO (1) WO2006004778A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8852672B2 (en) 2008-01-28 2014-10-07 Biomet 3I, Llc Implant surface with increased hydrophilicity

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0702577D0 (en) * 2007-02-09 2007-03-21 Ucl Business Plc An article and a method of surface treatment of an article
DE102008053892A1 (en) 2008-10-30 2010-05-06 Fachhochschule Gelsenkirchen Medical implant with bio-functionalized surface
FR2938271B1 (en) * 2008-11-13 2011-09-02 Univ Reims Champagne Ardenne Method for electrodeposition coatings of calcium phosphate on metallic substrates, coatings and implantable material comprising such coatings
US8470967B2 (en) * 2010-09-24 2013-06-25 Duke University Phase transition biopolymers and methods of use
EP2636415A4 (en) * 2010-11-04 2015-03-25 Sanyo Chemical Ind Ltd Cell adhesive material for biological tissue
WO2012159216A1 (en) * 2011-05-25 2012-11-29 Kane Biotech Inc. Bone tissue regenerating peptides

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5205921A (en) * 1991-02-04 1993-04-27 Queen's University At Kingston Method for depositing bioactive coatings on conductive substrates
US6129928A (en) * 1997-09-05 2000-10-10 Icet, Inc. Biomimetic calcium phosphate implant coatings and methods for making the same
US6268348B1 (en) * 1989-08-14 2001-07-31 The Regents Of The University Of California Synthetic compounds and compositions with enhanced cell binding
DE10006992A1 (en) * 2000-02-16 2001-09-06 Aesculap Ag & Co Kg Method of coating implantate used as bone prosthesis by electrolytic deposition of soluble calcium phosphate comprises incorporation of dispersion particles
EP1166804A2 (en) * 2000-06-21 2002-01-02 MERCK PATENT GmbH Bone-like coating for metallic implant materials
DE10119096A1 (en) * 2001-04-19 2002-10-24 Keramed Medizintechnik Gmbh New biologically functionalized coatings, useful for e.g. accelerating osteo-integration of implants, e.g. dental or joint implants, comprise resorbable calcium-phosphorus phase containing adhesion and/or signal proteins

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6268348B1 (en) * 1989-08-14 2001-07-31 The Regents Of The University Of California Synthetic compounds and compositions with enhanced cell binding
US5205921A (en) * 1991-02-04 1993-04-27 Queen's University At Kingston Method for depositing bioactive coatings on conductive substrates
US6129928A (en) * 1997-09-05 2000-10-10 Icet, Inc. Biomimetic calcium phosphate implant coatings and methods for making the same
DE10006992A1 (en) * 2000-02-16 2001-09-06 Aesculap Ag & Co Kg Method of coating implantate used as bone prosthesis by electrolytic deposition of soluble calcium phosphate comprises incorporation of dispersion particles
EP1166804A2 (en) * 2000-06-21 2002-01-02 MERCK PATENT GmbH Bone-like coating for metallic implant materials
US20040033249A1 (en) * 2000-06-21 2004-02-19 Merck Patent Gesellschaft Mit Beschrankter Haftung Process for the coating for metallic implant materials
DE10119096A1 (en) * 2001-04-19 2002-10-24 Keramed Medizintechnik Gmbh New biologically functionalized coatings, useful for e.g. accelerating osteo-integration of implants, e.g. dental or joint implants, comprise resorbable calcium-phosphorus phase containing adhesion and/or signal proteins

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZREIQAT H ET AL: "Differentiation of human bone-derived cells grown on GRGDSP-peptide bound titanium surfaces." JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, vol. 64A, no. 1, 1 January 2003 (2003-01-01), pages 105-113, XP002358271 ISSN: 0021-9304 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8852672B2 (en) 2008-01-28 2014-10-07 Biomet 3I, Llc Implant surface with increased hydrophilicity
US9198742B2 (en) 2008-01-28 2015-12-01 Biomet 3I, Llc Implant surface with increased hydrophilicity

Also Published As

Publication number Publication date
WO2006004778A2 (en) 2006-01-12

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