WO2006004778A3 - Implant with a biofunctionalized surface and method for its production - Google Patents

Implant with a biofunctionalized surface and method for its production

Info

Publication number
WO2006004778A3
WO2006004778A3 PCT/US2005/022973 US2005022973W WO2006004778A3 WO 2006004778 A3 WO2006004778 A3 WO 2006004778A3 US 2005022973 W US2005022973 W US 2005022973W WO 2006004778 A3 WO2006004778 A3 WO 2006004778A3
Authority
WO
WIPO (PCT)
Prior art keywords
implant
production
peptide
apatite
biofunctionalized surface
Prior art date
Application number
PCT/US2005/022973
Other languages
French (fr)
Other versions
WO2006004778A2 (en
Inventor
Klaus Becker
Susanne Bierbaum
Dieter Scharnweber
Worch Hartmut
Original Assignee
Dentsply Int Inc
Klaus Becker
Susanne Bierbaum
Dieter Scharnweber
Worch Hartmut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dentsply Int Inc, Klaus Becker, Susanne Bierbaum, Dieter Scharnweber, Worch Hartmut filed Critical Dentsply Int Inc
Publication of WO2006004778A2 publication Critical patent/WO2006004778A2/en
Publication of WO2006004778A3 publication Critical patent/WO2006004778A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/25—Peptides having up to 20 amino acids in a defined sequence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A dental implant is described that includes a surface coating of a nanocrystalline apatite layer that is applied electrochemically. A peptide that has an osteoconductive effect is included in an electrolyte solution resulting in a co-deposition with the apatite such that the peptide remains effective in promoting cell adhesion.
PCT/US2005/022973 2004-06-30 2005-06-27 Implant with a biofunctionalized surface and method for its production WO2006004778A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP0401534.8 2004-06-30
EP04001534 2004-06-30

Publications (2)

Publication Number Publication Date
WO2006004778A2 WO2006004778A2 (en) 2006-01-12
WO2006004778A3 true WO2006004778A3 (en) 2006-03-09

Family

ID=35432312

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/022973 WO2006004778A2 (en) 2004-06-30 2005-06-27 Implant with a biofunctionalized surface and method for its production

Country Status (1)

Country Link
WO (1) WO2006004778A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8852672B2 (en) 2008-01-28 2014-10-07 Biomet 3I, Llc Implant surface with increased hydrophilicity

Families Citing this family (23)

* Cited by examiner, † Cited by third party
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GB0702577D0 (en) * 2007-02-09 2007-03-21 Ucl Business Plc An article and a method of surface treatment of an article
DE102008053892A1 (en) 2008-10-30 2010-05-06 Fachhochschule Gelsenkirchen Medical implant with biofunctionalized surface
FR2938271B1 (en) * 2008-11-13 2011-09-02 Univ Reims Champagne Ardenne PROCESS FOR THE ELECTRODEPOSITION OF PHOSPHOCALCIUM COATINGS ON METALLIC SUBSTRATES, COATINGS OBTAINED AND IMPLANTABLE MATERIALS COMPRISING SUCH COATINGS
US8470967B2 (en) * 2010-09-24 2013-06-25 Duke University Phase transition biopolymers and methods of use
WO2012060351A1 (en) 2010-11-04 2012-05-10 三洋化成工業株式会社 Cell adhesive material for biological tissue
WO2012159216A1 (en) * 2011-05-25 2012-11-29 Kane Biotech Inc. Bone tissue regenerating peptides
US10392611B2 (en) 2013-05-30 2019-08-27 Duke University Polymer conjugates having reduced antigenicity and methods of using the same
US10364451B2 (en) 2013-05-30 2019-07-30 Duke University Polymer conjugates having reduced antigenicity and methods of using the same
US10385115B2 (en) 2015-03-26 2019-08-20 Duke University Fibronectin type III domain-based fusion proteins
JP6882782B2 (en) 2015-08-04 2021-06-02 デューク ユニバーシティ Genetically encoded, essentially chaotic delivery stealth polymers and how to use them
US11752213B2 (en) 2015-12-21 2023-09-12 Duke University Surfaces having reduced non-specific binding and antigenicity
US11467156B2 (en) 2016-06-01 2022-10-11 Duke University Nonfouling biosensors
CA3031471A1 (en) 2016-07-25 2018-02-01 Cerapedics, Inc. Peptide-coated calcium phosphate particles
RU2019110848A (en) 2016-09-14 2020-10-15 Дьюк Юниверсити NANOPARTICLES BASED ON TRIBLOC POLYPEPTIDES FOR DELIVERY OF HYDROPHILIC MEDICINES
WO2018057847A1 (en) 2016-09-23 2018-03-29 Duke University Unstructured non-repetitive polypeptides having lcst behavior
WO2018132732A1 (en) 2017-01-12 2018-07-19 Duke University Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly
WO2018213320A1 (en) 2017-05-15 2018-11-22 Duke University Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents
WO2019006374A1 (en) 2017-06-30 2019-01-03 Duke University Order and disorder as a design principle for stimuli-responsive biopolymer networks
US11235086B2 (en) 2018-02-22 2022-02-01 Cerapedics, Inc. Processes for coating inorganic particles with a peptide or protein useful for improving cellular activity related to bone growth
EP3829622A4 (en) 2018-08-02 2022-05-11 Duke University Dual agonist fusion proteins
EP3919022A4 (en) 2019-01-31 2022-03-16 Cell-Medicine, Inc. Inorganic salt-protein composite medical instrument
US11512314B2 (en) 2019-07-12 2022-11-29 Duke University Amphiphilic polynucleotides
CN112604028B (en) * 2020-10-19 2023-02-17 北京联袂义齿技术有限公司 Surface coating for implant and preparation method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5205921A (en) * 1991-02-04 1993-04-27 Queen's University At Kingston Method for depositing bioactive coatings on conductive substrates
US6129928A (en) * 1997-09-05 2000-10-10 Icet, Inc. Biomimetic calcium phosphate implant coatings and methods for making the same
US6268348B1 (en) * 1989-08-14 2001-07-31 The Regents Of The University Of California Synthetic compounds and compositions with enhanced cell binding
DE10006992A1 (en) * 2000-02-16 2001-09-06 Aesculap Ag & Co Kg Method of coating implantate used as bone prosthesis by electrolytic deposition of soluble calcium phosphate comprises incorporation of dispersion particles
EP1166804A2 (en) * 2000-06-21 2002-01-02 MERCK PATENT GmbH Bone-like coating for metallic implant materials
DE10119096A1 (en) * 2001-04-19 2002-10-24 Keramed Medizintechnik Gmbh New biologically functionalized coatings, useful for e.g. accelerating osteo-integration of implants, e.g. dental or joint implants, comprise resorbable calcium-phosphorus phase containing adhesion and/or signal proteins

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6268348B1 (en) * 1989-08-14 2001-07-31 The Regents Of The University Of California Synthetic compounds and compositions with enhanced cell binding
US5205921A (en) * 1991-02-04 1993-04-27 Queen's University At Kingston Method for depositing bioactive coatings on conductive substrates
US6129928A (en) * 1997-09-05 2000-10-10 Icet, Inc. Biomimetic calcium phosphate implant coatings and methods for making the same
DE10006992A1 (en) * 2000-02-16 2001-09-06 Aesculap Ag & Co Kg Method of coating implantate used as bone prosthesis by electrolytic deposition of soluble calcium phosphate comprises incorporation of dispersion particles
EP1166804A2 (en) * 2000-06-21 2002-01-02 MERCK PATENT GmbH Bone-like coating for metallic implant materials
US20040033249A1 (en) * 2000-06-21 2004-02-19 Merck Patent Gesellschaft Mit Beschrankter Haftung Process for the coating for metallic implant materials
DE10119096A1 (en) * 2001-04-19 2002-10-24 Keramed Medizintechnik Gmbh New biologically functionalized coatings, useful for e.g. accelerating osteo-integration of implants, e.g. dental or joint implants, comprise resorbable calcium-phosphorus phase containing adhesion and/or signal proteins

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZREIQAT H ET AL: "Differentiation of human bone-derived cells grown on GRGDSP-peptide bound titanium surfaces.", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, vol. 64A, no. 1, 1 January 2003 (2003-01-01), pages 105 - 113, XP002358271, ISSN: 0021-9304 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8852672B2 (en) 2008-01-28 2014-10-07 Biomet 3I, Llc Implant surface with increased hydrophilicity
US9198742B2 (en) 2008-01-28 2015-12-01 Biomet 3I, Llc Implant surface with increased hydrophilicity

Also Published As

Publication number Publication date
WO2006004778A2 (en) 2006-01-12

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