WO2006002887A8 - Aqueous drink solution of indibulin (d-24851) and an organic acid - Google Patents

Aqueous drink solution of indibulin (d-24851) and an organic acid

Info

Publication number
WO2006002887A8
WO2006002887A8 PCT/EP2005/006991 EP2005006991W WO2006002887A8 WO 2006002887 A8 WO2006002887 A8 WO 2006002887A8 EP 2005006991 W EP2005006991 W EP 2005006991W WO 2006002887 A8 WO2006002887 A8 WO 2006002887A8
Authority
WO
WIPO (PCT)
Prior art keywords
indibulin
organic acid
drink solution
aqueous drink
aqueous
Prior art date
Application number
PCT/EP2005/006991
Other languages
French (fr)
Other versions
WO2006002887A1 (en
Inventor
Berthold Roessler
Original Assignee
Baxter Int
Baxter Healthcare Sa
Berthold Roessler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102004031538A external-priority patent/DE102004031538A1/en
Application filed by Baxter Int, Baxter Healthcare Sa, Berthold Roessler filed Critical Baxter Int
Publication of WO2006002887A1 publication Critical patent/WO2006002887A1/en
Publication of WO2006002887A8 publication Critical patent/WO2006002887A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention relates to a pharmaceutical presentation form for the oral administration of a poorly soluble active compound (D-24 851; INN: indibulin) in the form of an aqueous drink solution, and a method for its preparation.
PCT/EP2005/006991 2004-06-29 2005-06-29 Aqueous drink solution of indibulin (d-24851) and an organic acid WO2006002887A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US58381504P 2004-06-29 2004-06-29
US60/583,815 2004-06-29
DE102004031538A DE102004031538A1 (en) 2004-06-29 2004-06-29 Presentation form (obtainable by dissolving indibulin in or with a highly concentrated organic acid), useful to orally administer poorly soluble active compound indibulin, comprises a poorly soluble active compound indibulin
DE102004031538.8 2004-06-29

Publications (2)

Publication Number Publication Date
WO2006002887A1 WO2006002887A1 (en) 2006-01-12
WO2006002887A8 true WO2006002887A8 (en) 2006-06-08

Family

ID=34971900

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/006991 WO2006002887A1 (en) 2004-06-29 2005-06-29 Aqueous drink solution of indibulin (d-24851) and an organic acid

Country Status (1)

Country Link
WO (1) WO2006002887A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060280787A1 (en) * 2005-06-14 2006-12-14 Baxter International Inc. Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4360523A (en) * 1980-05-16 1982-11-23 Bristol-Myers Company Pharmaceutical formulations of 4'-(9-acridinylamino)-methanesulfon-m-anisidide
DE19814838C2 (en) * 1998-04-02 2001-01-18 Asta Medica Ag Indolyl-3-glyoxylic acid derivatives with anti-tumor effects

Also Published As

Publication number Publication date
WO2006002887A1 (en) 2006-01-12

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