WO2006000753A3 - Use of flj40787, a protein involved in colon, colorectal, ovarian, lung and/or liver cancer - Google Patents

Use of flj40787, a protein involved in colon, colorectal, ovarian, lung and/or liver cancer Download PDF

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Publication number
WO2006000753A3
WO2006000753A3 PCT/GB2005/002389 GB2005002389W WO2006000753A3 WO 2006000753 A3 WO2006000753 A3 WO 2006000753A3 GB 2005002389 W GB2005002389 W GB 2005002389W WO 2006000753 A3 WO2006000753 A3 WO 2006000753A3
Authority
WO
WIPO (PCT)
Prior art keywords
flj40787
cancer
colorectal
colon
ovarian
Prior art date
Application number
PCT/GB2005/002389
Other languages
French (fr)
Other versions
WO2006000753A2 (en
Inventor
Alasdair Stamps
Original Assignee
Celltech R&D Ltd
Alasdair Stamps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltech R&D Ltd, Alasdair Stamps filed Critical Celltech R&D Ltd
Publication of WO2006000753A2 publication Critical patent/WO2006000753A2/en
Publication of WO2006000753A3 publication Critical patent/WO2006000753A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Abstract

The present invention relates to new uses of FLJ40787 in the diagnosis, screening, treatment and prophylaxis of colon cancer, colorectal cancer, ovarian cancer, lung cancer and/or liver cancer cancer. The invention also provides compositions comprising FLJ40787, including vaccines, antibodies that are immunospecific for FLJ40787 and agents which interact with or modulate the expression or activity of FLJ40787 or which modulate the expression of the nucleic acid which codes for FLJ40787.
PCT/GB2005/002389 2004-06-25 2005-06-17 Use of flj40787, a protein involved in colon, colorectal, ovarian, lung and/or liver cancer WO2006000753A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0414325.1 2004-06-25
GBGB0414325.1A GB0414325D0 (en) 2004-06-25 2004-06-25 A protein involved in cancer

Publications (2)

Publication Number Publication Date
WO2006000753A2 WO2006000753A2 (en) 2006-01-05
WO2006000753A3 true WO2006000753A3 (en) 2006-04-06

Family

ID=32800233

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2005/002389 WO2006000753A2 (en) 2004-06-25 2005-06-17 Use of flj40787, a protein involved in colon, colorectal, ovarian, lung and/or liver cancer

Country Status (2)

Country Link
GB (1) GB0414325D0 (en)
WO (1) WO2006000753A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1900824A1 (en) * 2006-09-14 2008-03-19 Deutsches Krebsforschungszentrum Stiftung Des Öffentlichen Rechts Gene expression signature for the prognosis, diagnosis and therapy of prostate cancer and uses thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001029221A2 (en) * 1999-10-20 2001-04-26 Zymogenetics, Inc. Proteins and polynucleotides encoding them
WO2002016388A1 (en) * 2000-08-18 2002-02-28 Human Genome Sciences, Inc. 21 human secreted proteins
WO2002063006A2 (en) * 2001-02-06 2002-08-15 Incyte Genomics, Inc. Receptors and membrane-associated proteins
WO2004028479A2 (en) * 2002-09-25 2004-04-08 Genentech, Inc. Nouvelles compositions et methodes de traitement du psoriasis
WO2004043397A2 (en) * 2002-11-12 2004-05-27 Genentech, Inc. Compositions and methods for the treatment of rheumatoid arthritis

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001029221A2 (en) * 1999-10-20 2001-04-26 Zymogenetics, Inc. Proteins and polynucleotides encoding them
WO2002016388A1 (en) * 2000-08-18 2002-02-28 Human Genome Sciences, Inc. 21 human secreted proteins
WO2002063006A2 (en) * 2001-02-06 2002-08-15 Incyte Genomics, Inc. Receptors and membrane-associated proteins
WO2004028479A2 (en) * 2002-09-25 2004-04-08 Genentech, Inc. Nouvelles compositions et methodes de traitement du psoriasis
WO2004043397A2 (en) * 2002-11-12 2004-05-27 Genentech, Inc. Compositions and methods for the treatment of rheumatoid arthritis

Also Published As

Publication number Publication date
GB0414325D0 (en) 2004-07-28
WO2006000753A2 (en) 2006-01-05

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