WO2005110460A3 - Méthodes de traitement et diagnostics relatifs au vieillissement, particulièrement celui des muscles (14.1) - Google Patents

Méthodes de traitement et diagnostics relatifs au vieillissement, particulièrement celui des muscles (14.1) Download PDF

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Publication number
WO2005110460A3
WO2005110460A3 PCT/US2005/014441 US2005014441W WO2005110460A3 WO 2005110460 A3 WO2005110460 A3 WO 2005110460A3 US 2005014441 W US2005014441 W US 2005014441W WO 2005110460 A3 WO2005110460 A3 WO 2005110460A3
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WO
WIPO (PCT)
Prior art keywords
aging
muscle
diagnosis
treatment methods
methods related
Prior art date
Application number
PCT/US2005/014441
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English (en)
Other versions
WO2005110460A2 (fr
Inventor
John J Kopchick
Karen T Coschigano
Keith S Boyce
Andres Kriete
Original Assignee
Univ Ohio
Icoria Inc
John J Kopchick
Karen T Coschigano
Keith S Boyce
Andres Kriete
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ohio, Icoria Inc, John J Kopchick, Karen T Coschigano, Keith S Boyce, Andres Kriete filed Critical Univ Ohio
Publication of WO2005110460A2 publication Critical patent/WO2005110460A2/fr
Publication of WO2005110460A3 publication Critical patent/WO2005110460A3/fr

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Une expression différente des gènes des souris en comparaison à l’expression des gènes selon l'âge des muscles des souris a été découverte et correspond aux gènes et protéines humaines. Les molécules humaines, ou antagonistes, peuvent être utilisées pour se protéger contre un vieillissement biologique plus rapide que la norme ou pour obtenir un vieillissement biologique plus lent que la norme. Les molécules humaines peuvent aussi être utilisées comme des indicateurs de vieillissement biologique.
PCT/US2005/014441 2004-04-29 2005-04-28 Méthodes de traitement et diagnostics relatifs au vieillissement, particulièrement celui des muscles (14.1) WO2005110460A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US56606804P 2004-04-29 2004-04-29
US60/566,068 2004-04-29
US57793004P 2004-06-09 2004-06-09
US60/577,930 2004-06-09

Publications (2)

Publication Number Publication Date
WO2005110460A2 WO2005110460A2 (fr) 2005-11-24
WO2005110460A3 true WO2005110460A3 (fr) 2006-04-13

Family

ID=34969798

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/014441 WO2005110460A2 (fr) 2004-04-29 2005-04-28 Méthodes de traitement et diagnostics relatifs au vieillissement, particulièrement celui des muscles (14.1)

Country Status (1)

Country Link
WO (1) WO2005110460A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109540890A (zh) * 2018-11-27 2019-03-29 湖南品胜生物技术有限公司 一种基于细胞显微镜图像的dna定量分析方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0512401D0 (en) * 2005-06-17 2005-07-27 Randox Lab Ltd Method
KR101960954B1 (ko) * 2017-06-21 2019-03-22 한국생명공학연구원 혈액 바이오마커를 이용한 근력 약화 관련 질환의 진단 방법 및 키트
CN113667739B (zh) * 2021-08-27 2023-12-26 河北医科大学第二医院 冠状动脉疾病的诊断标志物组合

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002074911A2 (fr) * 2001-03-19 2002-09-26 Wisconsin Alumni Research Foundation Identification des alterations de l'expression genetique qui accompagnent le processus de vieillissement des mammiferes
WO2003025122A2 (fr) * 2001-08-13 2003-03-27 University Of Kentucky Research Foundation Biomarqueurs de profil d'expression genique et cibles therapeutiques destines au vieillissement cerebral et a la deficience intellectuelle liee a l'age

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002074911A2 (fr) * 2001-03-19 2002-09-26 Wisconsin Alumni Research Foundation Identification des alterations de l'expression genetique qui accompagnent le processus de vieillissement des mammiferes
WO2003025122A2 (fr) * 2001-08-13 2003-03-27 University Of Kentucky Research Foundation Biomarqueurs de profil d'expression genique et cibles therapeutiques destines au vieillissement cerebral et a la deficience intellectuelle liee a l'age

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BODYAK NATALYA ET AL: "Gene expression profiling of the aging mouse cardiac myocytes", NUCLEIC ACIDS RESEARCH, vol. 30, no. 17, 1 September 2002 (2002-09-01), pages 3788 - 3794, XP002341760, ISSN: 0305-1048 *
BRONIKOWSKI A M ET AL: "Lifelong voluntary exercise in the mouse prevents age-related alterations in gene expression in the heart.", PHYSIOLOGICAL GENOMICS. 15 JAN 2003, vol. 12, no. 2, 15 January 2003 (2003-01-15), pages 129 - 138, XP002341762, ISSN: 1531-2267 *
LEE CHEOL-KOO ET AL: "Gene expression profile of aging and its retardation by caloric restriction", SCIENCE (WASHINGTON D C), vol. 285, no. 5432, 27 August 1999 (1999-08-27), pages 1390 - 1393, XP002341761, ISSN: 0036-8075 *
WEINDRUCH R ET AL: "Gene expression profiling of aging using DNA microarrays", MECHANISMS OF AGEING AND DEVELOPMENT, ELSEVIER SEQUOIA, LAUSANNE,, CH, vol. 123, 2002, pages 177 - 193, XP002304151, ISSN: 0047-6374 *
WEINDRUCH R ET AL: "Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice", JOURNAL OF NUTRITION, WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, PHILADELPHIA, PA,, US, vol. 131, no. 3, March 2001 (2001-03-01), pages 918S - 923S, XP002961487, ISSN: 0022-3166 *
WELLE S ET AL: "Gene expression profile of aging in human muscle", PHYSIOLOGICAL GENOMICS 2003 UNITED STATES, vol. 14, 2003, pages 149 - 159, XP002341763, ISSN: 1531-2267 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109540890A (zh) * 2018-11-27 2019-03-29 湖南品胜生物技术有限公司 一种基于细胞显微镜图像的dna定量分析方法

Also Published As

Publication number Publication date
WO2005110460A2 (fr) 2005-11-24

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