WO2005106006A3 - Biotransformation of nicotinic acid to 6-hydroxynicotinic acid - Google Patents

Biotransformation of nicotinic acid to 6-hydroxynicotinic acid Download PDF

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Publication number
WO2005106006A3
WO2005106006A3 PCT/IN2004/000172 IN2004000172W WO2005106006A3 WO 2005106006 A3 WO2005106006 A3 WO 2005106006A3 IN 2004000172 W IN2004000172 W IN 2004000172W WO 2005106006 A3 WO2005106006 A3 WO 2005106006A3
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WO
WIPO (PCT)
Prior art keywords
acid
biotransformation
hydroxynicotinic
nicotinic acid
nicotinic
Prior art date
Application number
PCT/IN2004/000172
Other languages
French (fr)
Other versions
WO2005106006A2 (en
Inventor
Tankeswar Nath
Prabhat Goel
Shiv Kumar Mishra
Ashutosh Agarwal
Original Assignee
Jubilant Organosys Ltd
Tankeswar Nath
Prabhat Goel
Shiv Kumar Mishra
Ashutosh Agarwal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jubilant Organosys Ltd, Tankeswar Nath, Prabhat Goel, Shiv Kumar Mishra, Ashutosh Agarwal filed Critical Jubilant Organosys Ltd
Publication of WO2005106006A2 publication Critical patent/WO2005106006A2/en
Publication of WO2005106006A3 publication Critical patent/WO2005106006A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)

Abstract

Disclosed herein is a process for producing 6-hydroxynicotinic acid via biotransformation, the process comprises hydroxylation of nicotinic acid in aqueous medium using a novel microbial strain, Yersinia pseudotuberculosis MTCC 5129 cells having nicotinic acid hydroxylase enzyme activity under mild reaction conditions.
PCT/IN2004/000172 2004-05-05 2004-06-17 Biotransformation of nicotinic acid to 6-hydroxynicotinic acid WO2005106006A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN826DE2004 2004-05-05
IN826/DEL/2004 2004-05-05

Publications (2)

Publication Number Publication Date
WO2005106006A2 WO2005106006A2 (en) 2005-11-10
WO2005106006A3 true WO2005106006A3 (en) 2007-11-29

Family

ID=35242264

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2004/000172 WO2005106006A2 (en) 2004-05-05 2004-06-17 Biotransformation of nicotinic acid to 6-hydroxynicotinic acid

Country Status (1)

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WO (1) WO2005106006A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104263767A (en) * 2014-10-01 2015-01-07 青岛科技大学 Method for producing iodophenyl methyl propionate through reduction by virtue of candida utilis
CN112011490B (en) * 2020-09-16 2022-07-19 安徽瑞邦生物科技有限公司 Pseudomonas putida strain and application thereof in degrading nicotinic acid

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4738924A (en) * 1984-02-22 1988-04-19 Lonza Ltd. Method for the production of 6-hydroxynicotinic acid
US5151351A (en) * 1989-12-20 1992-09-29 Lonza Ltd. Process for the production of 6-hydroxynicotinic acid

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4738924A (en) * 1984-02-22 1988-04-19 Lonza Ltd. Method for the production of 6-hydroxynicotinic acid
US5151351A (en) * 1989-12-20 1992-09-29 Lonza Ltd. Process for the production of 6-hydroxynicotinic acid

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NAGASAWA ET AL.: "Production of 6-hydroxynicotinic acid from nicotinic acid by resting cells of Pseudomonas fluorescens TN5", BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, vol. 58, no. 4, 1994, pages 665 - 668 *

Also Published As

Publication number Publication date
WO2005106006A2 (en) 2005-11-10

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