WO2005103709A1 - Diagnostics et therapeutiques pour des maladies associees au recepteur humain couple a la proteine g fksg79 (fksg79) - Google Patents

Diagnostics et therapeutiques pour des maladies associees au recepteur humain couple a la proteine g fksg79 (fksg79) Download PDF

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Publication number
WO2005103709A1
WO2005103709A1 PCT/EP2005/003824 EP2005003824W WO2005103709A1 WO 2005103709 A1 WO2005103709 A1 WO 2005103709A1 EP 2005003824 W EP2005003824 W EP 2005003824W WO 2005103709 A1 WO2005103709 A1 WO 2005103709A1
Authority
WO
WIPO (PCT)
Prior art keywords
diseases
fksg79
polypeptide
infections
cancer
Prior art date
Application number
PCT/EP2005/003824
Other languages
English (en)
Inventor
Stefan Golz
Ulf Brüggemeier
Andreas Geerts
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of WO2005103709A1 publication Critical patent/WO2005103709A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Abstract

L'invention concerne un FKSG79 humain associé aux maladies cardio-vasculaires, infections, maladies dermatologiques, maladies gastroentérologiques, cancer, inflammation, maladies métaboliques, maladies hématologiques, maladies respiratoires, maladies du squelette et des muscles, maladies neurologiques et maladies des voies urinaires. L'invention concerne également des analyses pour l'identification de composés utiles dans le traitement ou la prévention de maladies cardio-vasculaires, infections, maladies dermatologiques, maladies gastroentérologiques, cancer, inflammation, maladies métaboliques, maladies hématologiques, maladies respiratoires, maladies du squelette et des muscles, maladies neurologiques et maladies des voies urinaires. L'invention concerne également des composés qui se lient à et/ou activent ou inhibent l'activité de FKSG79 ainsi que des compositions pharmaceutiques comprenant de tels composés.
PCT/EP2005/003824 2004-04-24 2005-04-12 Diagnostics et therapeutiques pour des maladies associees au recepteur humain couple a la proteine g fksg79 (fksg79) WO2005103709A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04009781.8 2004-04-24
EP04009781 2004-04-24

Publications (1)

Publication Number Publication Date
WO2005103709A1 true WO2005103709A1 (fr) 2005-11-03

Family

ID=34965303

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/003824 WO2005103709A1 (fr) 2004-04-24 2005-04-12 Diagnostics et therapeutiques pour des maladies associees au recepteur humain couple a la proteine g fksg79 (fksg79)

Country Status (1)

Country Link
WO (1) WO2005103709A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10248582A (ja) * 1997-03-12 1998-09-22 Asahi Chem Ind Co Ltd 新規な７回膜貫通型受容体蛋白質ｊｅｇ１８
WO2002061087A2 (fr) * 2000-12-19 2002-08-08 Lifespan Biosciences, Inc. Peptides antigeniques destines a des recepteurs couples a la proteine g (gpcr), anticorps s'y rapportant, et systeme d'identification desdits peptides antigeniques
US20030191285A1 (en) * 2000-02-08 2003-10-09 Masanori Miwa Novel g protein-coupled receptor proteins and dnas thereof
WO2004040000A2 (fr) * 2002-09-09 2004-05-13 Nura, Inc Recepteurs couples a la proteine g et leurs utilisations

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10248582A (ja) * 1997-03-12 1998-09-22 Asahi Chem Ind Co Ltd 新規な７回膜貫通型受容体蛋白質ｊｅｇ１８
US20030191285A1 (en) * 2000-02-08 2003-10-09 Masanori Miwa Novel g protein-coupled receptor proteins and dnas thereof
WO2002061087A2 (fr) * 2000-12-19 2002-08-08 Lifespan Biosciences, Inc. Peptides antigeniques destines a des recepteurs couples a la proteine g (gpcr), anticorps s'y rapportant, et systeme d'identification desdits peptides antigeniques
WO2004040000A2 (fr) * 2002-09-09 2004-05-13 Nura, Inc Recepteurs couples a la proteine g et leurs utilisations

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
NEEF M ET AL: "PORTAL HYPERTENSION IS ASSOCIATED WITH INCREASED MRNA LEVELS OF VASOPRESSOR G-PROTEIN-COUPLED RECEPTORS IN HUMAN HEPATIC ARTERIES", EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, BLACKWELL SCIENTIFIC PUBLICATIONS, vol. 33, no. 3, March 2003 (2003-03-01), pages 249 - 255, XP008046935, ISSN: 0014-2972 *
PATENT ABSTRACTS OF JAPAN vol. 199, no. 814 31 December 1998 (1998-12-31) *

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