WO2005099822A3 - Reduction of drug / drug interactions with modafinil - Google Patents

Reduction of drug / drug interactions with modafinil Download PDF

Info

Publication number
WO2005099822A3
WO2005099822A3 PCT/US2005/012916 US2005012916W WO2005099822A3 WO 2005099822 A3 WO2005099822 A3 WO 2005099822A3 US 2005012916 W US2005012916 W US 2005012916W WO 2005099822 A3 WO2005099822 A3 WO 2005099822A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug
modafinil
reduction
interactions
drug interactions
Prior art date
Application number
PCT/US2005/012916
Other languages
French (fr)
Other versions
WO2005099822A2 (en
Inventor
Philmore Robertson
Original Assignee
Cephalon Inc
Philmore Robertson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc, Philmore Robertson filed Critical Cephalon Inc
Publication of WO2005099822A2 publication Critical patent/WO2005099822A2/en
Publication of WO2005099822A3 publication Critical patent/WO2005099822A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism

Abstract

Compositions and methods for the treatment of disorders through the administration of the R-isomer of modafinil.
PCT/US2005/012916 2004-04-13 2005-04-13 Reduction of drug / drug interactions with modafinil WO2005099822A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56159904P 2004-04-13 2004-04-13
US60/561,599 2004-04-13

Publications (2)

Publication Number Publication Date
WO2005099822A2 WO2005099822A2 (en) 2005-10-27
WO2005099822A3 true WO2005099822A3 (en) 2006-01-12

Family

ID=34979548

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/012916 WO2005099822A2 (en) 2004-04-13 2005-04-13 Reduction of drug / drug interactions with modafinil

Country Status (1)

Country Link
WO (1) WO2005099822A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160367503A1 (en) * 2015-06-20 2016-12-22 Cary Erwin Fechter Combination Medication for Neuro-Degenerative Diseases

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0233106A1 (en) * 1986-01-31 1987-08-19 Laboratoire L. Lafon (-)-Benzhydrylsulfinylacetamide, process for its preparation and its use in therapy
WO2004014846A1 (en) * 2002-08-09 2004-02-19 Cephalon France Modafinil polymorphic forms
WO2004024134A1 (en) * 2002-09-13 2004-03-25 Cephalon, Inc. Pharmaceutical formulations of modafinil
WO2004103359A1 (en) * 2003-05-16 2004-12-02 Cephalon, Inc. Pharmaceutical combination comprising modafinil and another drug
WO2005023198A2 (en) * 2003-09-04 2005-03-17 Cephalon, Inc. Modafinil compositions
WO2005077894A1 (en) * 2004-02-06 2005-08-25 Cephalon, Inc. Modafinil compositions

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0233106A1 (en) * 1986-01-31 1987-08-19 Laboratoire L. Lafon (-)-Benzhydrylsulfinylacetamide, process for its preparation and its use in therapy
WO2004014846A1 (en) * 2002-08-09 2004-02-19 Cephalon France Modafinil polymorphic forms
WO2004024134A1 (en) * 2002-09-13 2004-03-25 Cephalon, Inc. Pharmaceutical formulations of modafinil
WO2004103359A1 (en) * 2003-05-16 2004-12-02 Cephalon, Inc. Pharmaceutical combination comprising modafinil and another drug
WO2005023198A2 (en) * 2003-09-04 2005-03-17 Cephalon, Inc. Modafinil compositions
WO2005077894A1 (en) * 2004-02-06 2005-08-25 Cephalon, Inc. Modafinil compositions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DONOVAN, JENNIFER L. ET AL: "Chiral Analysis of d- and l-Modafinil in Human Serum: Application to Human Pharmacokinetic Studies", THERAPEUTIC DRUG MONITORING , 25(2), 197-202 CODEN: TDMODV; ISSN: 0163-4356, 2003, XP008055828 *
ROBERTSON PHILMORE ET AL: "In vitro inhibition and induction of human hepatic cytochrome P450 enzymes by modafinil", DRUG METABOLISM AND DISPOSITION, vol. 28, no. 6, June 2000 (2000-06-01), pages 664 - 671, XP008055865, ISSN: 0090-9556 *

Also Published As

Publication number Publication date
WO2005099822A2 (en) 2005-10-27

Similar Documents

Publication Publication Date Title
ZA200607433B (en) Methods and compositions for the treatment of gastroin-testinal disorders
TWI369987B (en) New pharmaceutical compositions for the treatment of hyper-proliferative disorders
EP1622589A4 (en) Compositions, targets, methods and devices for the therapy of ocular and periocular disorders
EP1893216A4 (en) Methods and compositions for the treatment of ocular disorders
IL177772A0 (en) Methods and compositions for the treatment of gastrointestinal disorders
WO2006002097A3 (en) Retinal derivatives and methods for the use thereof for the treatment of visual disorders
WO2008067389A3 (en) Modulation of sod protein synthesis for the treatment of neurodegenerative diseases
WO2008054676A3 (en) Medical devices and methods of using the same
WO2007051062A3 (en) Substituted dihydropyridines and methods of use
IL183963A0 (en) 1 - aminocyclohexane - derivatives for the treatment of multiple sclerosis, emotional liability and pseudobulbar affect
IL214198A0 (en) Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling
WO2006124748A3 (en) Multicyclic compounds and methods of their use
WO2010060937A3 (en) Pharmaceutical combination comprising a hsp 90 inhibitor and a mtor inhibitor
WO2006044825A3 (en) Mitotic kinesin inhibitors and methods of use thereof
EP1926521A4 (en) Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders
WO2006015259A3 (en) Compounds and compositions as modulators of steroid hormone nuclear receptors
IL180251A0 (en) Methods and reagents for the treatment of metabolic disorders
WO2007088034A3 (en) Tuberous sclerosis treatment
WO2006131591A3 (en) An entacapone-containing oral dosage form
WO2007050793A3 (en) Methods and compositions for the treatment of marfan syndrome and associated disorders
WO2006055871A3 (en) Treatment for multiple sclerosis
WO2007101161A8 (en) Methods and compositions for the treatment of gastrointestinal disorders
WO2008097924A3 (en) Pharmaceutical compositions comprising dextromethorphan analogs for the treatment of neurological disorders
AU2007243282A8 (en) Compositions and methods for the treatment of cardiovascular disease
WO2007122382A3 (en) Lycopene for the treatment of metabolic dysfunction

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

WWW Wipo information: withdrawn in national office

Country of ref document: DE

122 Ep: pct application non-entry in european phase