WO2005094902A3 - Agent de contraste destine a l'imagerie medicale - Google Patents

Agent de contraste destine a l'imagerie medicale Download PDF

Info

Publication number
WO2005094902A3
WO2005094902A3 PCT/IB2005/051021 IB2005051021W WO2005094902A3 WO 2005094902 A3 WO2005094902 A3 WO 2005094902A3 IB 2005051021 W IB2005051021 W IB 2005051021W WO 2005094902 A3 WO2005094902 A3 WO 2005094902A3
Authority
WO
WIPO (PCT)
Prior art keywords
optical imaging
contrast agent
nanoparticles
luminescent substances
core
Prior art date
Application number
PCT/IB2005/051021
Other languages
English (en)
Other versions
WO2005094902A2 (fr
Inventor
Claus Feldmann
Original Assignee
Philips Intellectual Property
Koninkl Philips Electronics Nv
Claus Feldmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Intellectual Property, Koninkl Philips Electronics Nv, Claus Feldmann filed Critical Philips Intellectual Property
Publication of WO2005094902A2 publication Critical patent/WO2005094902A2/fr
Publication of WO2005094902A3 publication Critical patent/WO2005094902A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/08—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
    • C09K11/77—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals
    • C09K11/7766—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing rare earth metals containing two or more rare earth metals
    • C09K11/7774—Aluminates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0065—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle
    • A61K49/0067—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle quantum dots, fluorescent nanocrystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0089—Particulate, powder, adsorbate, bead, sphere
    • A61K49/0091—Microparticle, microcapsule, microbubble, microsphere, microbead, i.e. having a size or diameter higher or equal to 1 micrometer
    • A61K49/0093—Nanoparticle, nanocapsule, nanobubble, nanosphere, nanobead, i.e. having a size or diameter smaller than 1 micrometer, e.g. polymeric nanoparticle
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/08—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
    • C09K11/57—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing manganese or rhenium
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/08—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials
    • C09K11/74—Luminescent, e.g. electroluminescent, chemiluminescent materials containing inorganic luminescent materials containing arsenic, antimony or bismuth

Abstract

L'invention concerne un agent de contraste destiné à l'imagerie optique comprenant des particules (1) comprenant au moins un noyau (2), ledit noyau comprenant des substances luminescentes qui absorbent et émettent un rayonnement électromagnétique à des longueurs d'ondes différentes.
PCT/IB2005/051021 2004-04-01 2005-03-24 Agent de contraste destine a l'imagerie medicale WO2005094902A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04101351.7 2004-04-01
EP04101351 2004-04-01

Publications (2)

Publication Number Publication Date
WO2005094902A2 WO2005094902A2 (fr) 2005-10-13
WO2005094902A3 true WO2005094902A3 (fr) 2006-05-26

Family

ID=34961991

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/051021 WO2005094902A2 (fr) 2004-04-01 2005-03-24 Agent de contraste destine a l'imagerie medicale

Country Status (1)

Country Link
WO (1) WO2005094902A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1920784A1 (fr) * 2006-11-13 2008-05-14 Koninklijke Philips Electronics N.V. Sensibilisateurs de radiation pour la thérapie par rayonnements ionisants et pour l'imagerie
DE102007039335A1 (de) * 2007-08-20 2009-02-26 Henkel Ag & Co. Kgaa Lumineszierende Kompositmaterialien
CN104178160A (zh) * 2013-05-22 2014-12-03 海洋王照明科技股份有限公司 铈铽双掺杂氮硅镧发光材料、制备方法及其应用
US10124072B2 (en) 2013-09-18 2018-11-13 Caliper Life Sciences, Inc. In-vivo reactive species imaging
US9642923B2 (en) 2014-02-24 2017-05-09 Verily Life Sciences Llc Engineered particles with polarization contrast and alignment control for enhanced imaging
KR102379752B1 (ko) * 2020-08-19 2022-03-28 국민대학교산학협력단 X-선 감쇠 기반 생체 이미징용 나노입자 및 조성물

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5893999A (en) * 1993-09-13 1999-04-13 Kabushiki Kaisha Toshiba Ultrafine inorganic phosphor, specifically binding material labeled with this phosphor, and detection method using this specific binding material
WO2001086299A2 (fr) * 2000-05-05 2001-11-15 Bayer Aktiengesellschaft Nanoparticules dopees servant de marqueurs biologiques
WO2003038011A2 (fr) * 2001-11-01 2003-05-08 Oxonica Limited Nanomateriaux luminescents
WO2003037788A1 (fr) * 2001-11-01 2003-05-08 Oxonica Limited Nanoparticules luminescentes hydrosolubles
US6699723B1 (en) * 1997-11-25 2004-03-02 The Regents Of The University Of California Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
WO2004018590A1 (fr) * 2002-08-20 2004-03-04 Oxonica Limited Composes luminescents
WO2005051846A2 (fr) * 2003-11-24 2005-06-09 Universite Claude Bernard Lyon I Procede de preparation d'une poudre submicronique, nanostructuree, de sesquioxyde, oxohydroxyde, hydroxyde ou oxyde mixte de terre rare
WO2005058360A2 (fr) * 2003-12-17 2005-06-30 Philips Intellectual Property & Standards Gmbh Radiotherapie et imagerie medicale au moyen de nanoparticules emettant des rayons ultraviolets

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5893999A (en) * 1993-09-13 1999-04-13 Kabushiki Kaisha Toshiba Ultrafine inorganic phosphor, specifically binding material labeled with this phosphor, and detection method using this specific binding material
US6699723B1 (en) * 1997-11-25 2004-03-02 The Regents Of The University Of California Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
WO2001086299A2 (fr) * 2000-05-05 2001-11-15 Bayer Aktiengesellschaft Nanoparticules dopees servant de marqueurs biologiques
WO2003038011A2 (fr) * 2001-11-01 2003-05-08 Oxonica Limited Nanomateriaux luminescents
WO2003037788A1 (fr) * 2001-11-01 2003-05-08 Oxonica Limited Nanoparticules luminescentes hydrosolubles
WO2004018590A1 (fr) * 2002-08-20 2004-03-04 Oxonica Limited Composes luminescents
WO2005051846A2 (fr) * 2003-11-24 2005-06-09 Universite Claude Bernard Lyon I Procede de preparation d'une poudre submicronique, nanostructuree, de sesquioxyde, oxohydroxyde, hydroxyde ou oxyde mixte de terre rare
WO2005058360A2 (fr) * 2003-12-17 2005-06-30 Philips Intellectual Property & Standards Gmbh Radiotherapie et imagerie medicale au moyen de nanoparticules emettant des rayons ultraviolets

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FELDMANN C ET AL: "INORGANIC LUMINESCENT MATERIALS: 100 YEARS OF RESEARCH AND APPLICATION", ADVANCED FUNCTIONAL MATERIALS, WILEY VCH, WIENHEIM, DE, vol. 13, no. 7, July 2003 (2003-07-01), pages 511 - 516, XP001164632, ISSN: 1616-301X *
TORCHILIN V P: "TAT PEPTIDE-MODIFIED LIPOSOMES FOR INTRACELLULAR DELIVERY OF DRUGS AND DNA", CELLULAR AND MOLECULAR BIOLOGY LETTERS, UNIVERSITY OF WROCAW. INSTITUTE OF BIOCHEMISTRY, WROCAW, PL, vol. 7, no. 2, 2002, pages 265 - 267, XP008061723, ISSN: 1425-8153 *
ZIJLMANS H J M A A ET AL: "Detection of cell and tissue surface antigens using up-converting phosphors: A new reporter technology", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS, SAN DIEGO, CA, US, vol. 267, no. 1, 1 February 1999 (1999-02-01), pages 30 - 36, XP002185942, ISSN: 0003-2697 *

Also Published As

Publication number Publication date
WO2005094902A2 (fr) 2005-10-13

Similar Documents

Publication Publication Date Title
TW200721543A (en) Optoelectronic component
WO2004067794A3 (fr) Extraction de composes organiques de materiaux nano-composites
WO2005094902A3 (fr) Agent de contraste destine a l'imagerie medicale
WO2006106513A3 (fr) Nouvelles nanoparticles de noyau et de noyau / coquille comprenant le iode et destinees a l'imagerie aux rayons x
WO2008076467A3 (fr) Procédés d'imagerie intraopératoire
AU2002307550A1 (en) Plasmonic nanophotonics methods, materials, and apparatuses
AU2002340310A1 (en) Broad spectrum light emitting devices and method for fabricating the same
WO2002080754A3 (fr) Methodes d'utilisation d'une annexine permettant de visualiser la mort cellulaire in vivo et de traiter des etats pathologiques
AU2001239182A1 (en) Semiconductor component which emits radiation, and method for producing the same
TW200712167A (en) Color converting material composition and color converting medium including the same
EP1850649A4 (fr) Film conducteur transmettant la lumiere, film de protection contre les ondes electromagnetiques transmettant la lumiere, filtre optique et procede de fabrication de filtre d'affichage
WO2008105301A1 (fr) Composition absorbant le rayonnement ultraviolet
WO2006060355A3 (fr) Nanocristaux multifonctionnels
WO2006038743A1 (fr) Article contenant une partie metallique, piece de monnaie et son procede de production
AU2002223114A1 (en) Ct detector-module having radiation shielding for the processing circuitry
HK1130278A1 (en) Silicate-base luminescent materials having multiple emission peaks, processes for preparing the same and light emitting devices using the same
EP1921473A4 (fr) Film conducteur d'ondes optique et son procédé de fabrication, film optoélectrique hybride incluant le film conducteur d'ondes, et dispositif électronique
WO2006093965A3 (fr) Materiaux de transport de charge en coronene, procedes pour les fabriquer et procedes pour les utiliser
AU2003289460A1 (en) Light emitting element and process for preparing the same
GB2470321B8 (en) Gearless locking differential.
WO2007009447A3 (fr) Boitier pour composant optoelectronique emettant du rayonnement electromagnetique, composant emettant du rayonnement electromagnetique, et procede pour realiser un boitier ou un composant de ce type
WO2009053876A3 (fr) Émetteurs dans l'ir proche excitables dans le spectre visible et leur application en matière d'imagerie biochimique et médicale
WO2009009288A8 (fr) Particules combinées de verre et de céramique utilisables en tant que blindage contre les interférences électromagnétiques
WO2008152891A1 (fr) Nanoparticules de substance luminescente émettant de la lumière dans l'infrarouge proche, leur procédé de fabrication et agent pour le marquage d'une substance biologique à l'aide de celles-ci
WO2007047932A3 (fr) Revetements thermodurcissables par nir/ir pour imagerie à lumiere dirigee

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

WWW Wipo information: withdrawn in national office

Country of ref document: DE

122 Ep: pct application non-entry in european phase