WO2005082050A3 - Analysis and screening of solid forms using the atomic pair distribution function - Google Patents

Analysis and screening of solid forms using the atomic pair distribution function Download PDF

Info

Publication number
WO2005082050A3
WO2005082050A3 PCT/US2005/006114 US2005006114W WO2005082050A3 WO 2005082050 A3 WO2005082050 A3 WO 2005082050A3 US 2005006114 W US2005006114 W US 2005006114W WO 2005082050 A3 WO2005082050 A3 WO 2005082050A3
Authority
WO
WIPO (PCT)
Prior art keywords
solid forms
sample
screening
analysis
distribution function
Prior art date
Application number
PCT/US2005/006114
Other languages
French (fr)
Other versions
WO2005082050A2 (en
Inventor
Simon Bates
Igor Ivanisevic
Original Assignee
Ssci Inc
Simon Bates
Igor Ivanisevic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ssci Inc, Simon Bates, Igor Ivanisevic filed Critical Ssci Inc
Priority to EP05723818A priority Critical patent/EP1751527A2/en
Priority to US10/590,204 priority patent/US20070243620A1/en
Publication of WO2005082050A2 publication Critical patent/WO2005082050A2/en
Publication of WO2005082050A3 publication Critical patent/WO2005082050A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N23/00—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
    • G01N23/20—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by using diffraction of the radiation by the materials, e.g. for investigating crystal structure; by using scattering of the radiation by the materials, e.g. for investigating non-crystalline materials; by using reflection of the radiation by the materials
    • G01N23/207—Diffractometry using detectors, e.g. using a probe in a central position and one or more displaceable detectors in circumferential positions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)

Abstract

A method that comprises providing a PDF trace of a first sample of a substance, providing a PDF trace of a second sample of the substance, and comparing the PDF traces to determine whether the substance of the first sample and the substance of the second sample have the same or different solid forms. This embodiment may be used, for example, to distinguish one solid form of a compound from another, to screen for new solid forms of a compound, or to determine whether a disordered crystalline compound has the same solid form as another crystalline sample of the compound.
PCT/US2005/006114 2004-02-24 2005-02-24 Analysis and screening of solid forms using the atomic pair distribution function WO2005082050A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP05723818A EP1751527A2 (en) 2004-02-24 2005-02-24 Analysis and screening of solid forms using the atomic pair distribution function
US10/590,204 US20070243620A1 (en) 2004-02-24 2005-02-24 Analysis and Screening of Solid Forms Using the Atomic Pair Distribution Function

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54697604P 2004-02-24 2004-02-24
US60/546,976 2004-02-24

Publications (2)

Publication Number Publication Date
WO2005082050A2 WO2005082050A2 (en) 2005-09-09
WO2005082050A3 true WO2005082050A3 (en) 2007-08-30

Family

ID=34910834

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2005/006114 WO2005082050A2 (en) 2004-02-24 2005-02-24 Analysis and screening of solid forms using the atomic pair distribution function
PCT/US2005/005914 WO2005082012A2 (en) 2004-02-24 2005-02-24 Analysis and screening of solid forms using the atomic pair distribution function

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2005/005914 WO2005082012A2 (en) 2004-02-24 2005-02-24 Analysis and screening of solid forms using the atomic pair distribution function

Country Status (2)

Country Link
EP (1) EP1751527A2 (en)
WO (2) WO2005082050A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007038398A1 (en) * 2005-09-26 2007-04-05 Ssci, Inc. Methods of characterizing compositions
RU2445314C9 (en) 2008-01-18 2013-04-10 Мерк Шарп Энд Домэ Корп. Beta-lactamase inhibitors

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BIZID A ET AL: "Study by diffraction of X-rays of liquid gallium between +50 and 110[deg.]C", PHYSICA STATUS SOLIDI A EAST GERMANY, vol. 23, no. 1, 16 May 1974 (1974-05-16), pages 135 - 145, XP002427512, ISSN: 0031-8965 *
HATTORI T ET AL: "Structure of liquid GaSb under pressure", JOURNAL OF NON-CRYSTALLINE SOLIDS, NORTH-HOLLAND PHYSICS PUBLISHING. AMSTERDAM, NL, vol. 312-314, October 2002 (2002-10-01), pages 26 - 29, XP004382656, ISSN: 0022-3093 *
HERMANN A ET AL: "Conformations and structures of desflurane and isoflurane", JOURNAL OF FLUORINE CHEMISTRY, ELSEVIER SEQUOIA, LAUSANNE, CH, vol. 101, no. 2, February 2000 (2000-02-01), pages 223 - 231, XP004244522, ISSN: 0022-1139 *
IKEYA T ET AL: "Change in the structure of niobium pentoxide due to mechanical and thermal treatments", JOURNAL OF NON-CRYSTALLINE SOLIDS NETHERLANDS, vol. 105, no. 3, November 1988 (1988-11-01), pages 243 - 250, XP002427513, ISSN: 0022-3093 *
MARTIN U. SCHMIDT: "The Role of Qualitative and Quantitative Analyses", WORKSHOP "PHARMACEUTICAL APPLICATIONS OF X-RAY POWDER DIFFRACTION", 31 August 2006 (2006-08-31), Geneva, pages 1 - 24, XP002427515, Retrieved from the Internet <URL:http://www.anorg.chemie.uni-frankfurt.de/AK_Schmidt/epdic.pdf> [retrieved on 20070330] *
SHETH, BATES, MULLER, GRANT: "Polymorphism in Piroxicam", CRYSTAL GROWTH & DESIGN, vol. 4, no. 6, 1 September 2004 (2004-09-01), pages 1091 - 1098, XP002427514 *
YAMAMURA SHIGEO ET AL: "Change of the microstructure of microcrystalline cellulose with grinding and compression", JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 49, no. 12, December 1997 (1997-12-01), pages 1178 - 1181, XP009081503, ISSN: 0022-3573 *

Also Published As

Publication number Publication date
WO2005082012A2 (en) 2005-09-09
EP1751527A2 (en) 2007-02-14
WO2005082050A2 (en) 2005-09-09

Similar Documents

Publication Publication Date Title
WO2006084130A3 (en) Ultra-sensitive detection systems using multidimension signals
WO2006110848A3 (en) Chromatographic and mass spectral data analysis
WO2007140270A3 (en) Analyzing information gathered using multiple analytical techniques
EP1865315A4 (en) Cell image analyzing method, cell image analyzing program, cell image analyzing device, screening method and screening device
WO2007084151A3 (en) Multiple trace portal detection systems
WO2008039946A3 (en) Integrated meter for analyzing biological samples
WO2007079229A3 (en) Devices and methods for enrichment and alteration of circulating tumor cells and other particles
WO2007003344A3 (en) Device for quantitative analysis of a metabolite profile
IL186918A0 (en) Spectroscopic method for the detection of analytes
WO2006098772A3 (en) Systems and methods for measurement optimization
TW200704927A (en) Mass spectrometric analysis of ligand conjugated magnetic nanoparticles
EP1885839A4 (en) Systems and methods for multiple analyte detection
ZA200709821B (en) TRPV1 agonist compounds and methods for making and using the same
GB2439032B (en) Method and system for sample testing
EP1939611A4 (en) Method for detecting sample supply condition, and analyzer
EP1853598A4 (en) Chemical probe compounds that become fluorescent upon reduction, and methods for their use
WO2007002527A3 (en) BIOMARKERS FOR OVARIAN CANCER: β-2 MICROGLOBULIN
WO2009151757A3 (en) Method and apparatus for forensic screening
WO2006116564A3 (en) Analytical instrumentation, appartuses, and methods
EP2037280A4 (en) Panel for analysis and analyzer using the same
EP1886122A4 (en) Apparatus,method and computer program for spectroscopic measurements and analysis
WO2008027253A3 (en) Method and apparatus for repairing samples included in container files having lost packets
EP1955201A4 (en) Methods and apparatus for processing business objects, electronic forms, and workflows
WO2005082050A3 (en) Analysis and screening of solid forms using the atomic pair distribution function
WO2006083316A3 (en) Multipoint method for identifying hazardous agents

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 2005723818

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2005723818

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 10590204

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 10590204

Country of ref document: US