WO2005081619A3 - Compounds and methods for increasing neurogenesis - Google Patents
Compounds and methods for increasing neurogenesis Download PDFInfo
- Publication number
- WO2005081619A3 WO2005081619A3 PCT/IB2004/004451 IB2004004451W WO2005081619A3 WO 2005081619 A3 WO2005081619 A3 WO 2005081619A3 IB 2004004451 W IB2004004451 W IB 2004004451W WO 2005081619 A3 WO2005081619 A3 WO 2005081619A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- compounds
- neurogenesis
- increasing neurogenesis
- modulating agents
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Psychology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2546843A CA2546843C (en) | 2003-11-20 | 2004-11-19 | Compounds and methods for increasing neurogenesis |
EP04821493A EP1750752A2 (en) | 2003-11-20 | 2004-11-19 | Compounds and methods for increasing neurogenesis |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IB2003/005311 WO2004045592A2 (en) | 2002-11-20 | 2003-11-20 | Compounds and methods for increasing neurogenesis |
IBPCT/IB03/05311 | 2003-11-20 | ||
US10/718,071 | 2003-11-20 | ||
US10/718,071 US20050009847A1 (en) | 2002-11-20 | 2003-11-20 | Compounds and methods for increasing neurogenesis |
US10/850,055 US6969702B2 (en) | 2002-11-20 | 2004-05-19 | Compounds and methods for increasing neurogenesis |
US10/850,055 | 2004-05-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005081619A2 WO2005081619A2 (en) | 2005-09-09 |
WO2005081619A3 true WO2005081619A3 (en) | 2007-04-19 |
Family
ID=34915966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2004/004451 WO2005081619A2 (en) | 2003-11-20 | 2004-11-19 | Compounds and methods for increasing neurogenesis |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1750752A2 (en) |
CA (1) | CA2546843C (en) |
WO (1) | WO2005081619A2 (en) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2647568A1 (en) * | 2006-03-31 | 2007-10-11 | Amylin Pharmaceuticals, Inc. | Amylin and amylin agonists for treating psychiatric diseases and disorders |
CA2672524C (en) * | 2006-12-14 | 2016-08-23 | Neuronova Ab | Treatment of disease or injury of the nervous system using agents that decrease the activity of the melanocortin 4 receptor |
CA2699087A1 (en) * | 2007-09-11 | 2009-04-16 | Dorian Bevec | Use of a peptide as a therapeutic agent |
CA2698690A1 (en) * | 2007-09-11 | 2009-04-09 | Mondobiotech Laboratories Ag | Thyrotropin releasing hormone for therapeutic applications |
WO2009033809A2 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of a peptide as a therapeutic agent |
US20110263642A1 (en) * | 2008-08-26 | 2011-10-27 | Fibrogen, Inc. | Methods for treatment of multiple sclerosis |
CN102924587B (en) * | 2011-08-11 | 2016-08-24 | 中肽生化有限公司 | Long-acting salmon calcitonin analogues and its production and use |
UA116217C2 (en) | 2012-10-09 | 2018-02-26 | Санофі | Exendin-4 derivatives as dual glp1/glucagon agonists |
CN104870009B (en) | 2012-12-21 | 2021-05-18 | 赛诺菲 | Functionalized exendin-4 derivatives |
TW201609795A (en) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | EXENDIN-4 peptide analogues as dual GLP-1/GIP receptor agonists |
EP3080152A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Non-acylated exendin-4 peptide analogues |
EP3080149A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Dual glp-1/glucagon receptor agonists |
EP3080154B1 (en) | 2013-12-13 | 2018-02-07 | Sanofi | Dual glp-1/gip receptor agonists |
TW201625669A (en) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | Peptidic dual GLP-1/glucagon receptor agonists derived from Exendin-4 |
TW201625670A (en) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | Dual GLP-1/glucagon receptor agonists derived from EXENDIN-4 |
TW201625668A (en) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | Exendin-4 derivatives as peptidic dual GLP-1/glucagon receptor agonists |
US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
CN104888198A (en) * | 2015-04-21 | 2015-09-09 | 徐志强 | New application of calcitonin to preparing medicines for delaying brain aging |
AR105319A1 (en) | 2015-06-05 | 2017-09-27 | Sanofi Sa | PROPHARMS THAT INCLUDE A DUAL AGONIST GLU-1 / GLUCAGON CONJUGATE HIALURONIC ACID CONNECTOR |
TW201706291A (en) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | New EXENDIN-4 derivatives as selective peptidic dual GLP-1/glucagon receptor agonists |
US10883132B2 (en) * | 2018-03-09 | 2021-01-05 | Enzypep B.V. | Chemo-enzymatic synthesis of Semaglutide, Liraglutide and GLP-1 |
CN115896029A (en) * | 2023-01-09 | 2023-04-04 | 中国人民解放军军事科学院军事医学研究院 | Application of calcitonin gene-related peptide in treating Parkinson's disease |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000012099A1 (en) * | 1998-09-02 | 2000-03-09 | The Regents Of The University Of California | Promoters of neural regeneration |
WO2004045592A2 (en) * | 2002-11-20 | 2004-06-03 | Neuronova Ab | Compounds and methods for increasing neurogenesis |
-
2004
- 2004-11-19 WO PCT/IB2004/004451 patent/WO2005081619A2/en active Application Filing
- 2004-11-19 CA CA2546843A patent/CA2546843C/en not_active Expired - Fee Related
- 2004-11-19 EP EP04821493A patent/EP1750752A2/en not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000012099A1 (en) * | 1998-09-02 | 2000-03-09 | The Regents Of The University Of California | Promoters of neural regeneration |
WO2004045592A2 (en) * | 2002-11-20 | 2004-06-03 | Neuronova Ab | Compounds and methods for increasing neurogenesis |
Non-Patent Citations (4)
Title |
---|
PERRY TRACYANN ET AL: "A novel neurotrophic property of glucagon-like peptide 1: A promoter of nerve growth factor-mediated differentiation in PC12 cells", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 300, no. 3, March 2002 (2002-03-01), pages 958 - 966, XP002402955, ISSN: 0022-3565 * |
PERRY TRACYANN ET AL: "Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 302, no. 3, September 2002 (2002-09-01), pages 881 - 888, XP002402954, ISSN: 0022-3565 * |
RYDEL R E ET AL: "CAMP ANALOGS PROMOTE SURVIVAL AND NEURITE OUTGROWTH IN CULTURES OF RAT SYMPATHETIC AND SENSORY NEURONS INDEPENDENTLY OF NERVE GROWTH FACTOR", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 85, February 1988 (1988-02-01), pages 1257 - 1261, XP002923654, ISSN: 0027-8424 * |
THORNE R G ET AL: "DELIVERY OF NEUROTROPHIC FACTORS TO THE CENTRAL NERVOUS SYSTEM - PHARMACOKINETIC CONSIDERATIONS", CLINICAL PHARMACOKINETICS, LEA & FEBIGER, PHILADELPHIA, PA, US, vol. 40, no. 12, 2001, pages 907 - 946, XP009071751 * |
Also Published As
Publication number | Publication date |
---|---|
CA2546843A1 (en) | 2005-09-09 |
WO2005081619A2 (en) | 2005-09-09 |
CA2546843C (en) | 2015-01-06 |
EP1750752A2 (en) | 2007-02-14 |
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