WO2005070398A3 - Pharmaceutical compositions of candesartan cilexetil stabilized with co-solvents - Google Patents

Pharmaceutical compositions of candesartan cilexetil stabilized with co-solvents Download PDF

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Publication number
WO2005070398A3
WO2005070398A3 PCT/IB2005/000156 IB2005000156W WO2005070398A3 WO 2005070398 A3 WO2005070398 A3 WO 2005070398A3 IB 2005000156 W IB2005000156 W IB 2005000156W WO 2005070398 A3 WO2005070398 A3 WO 2005070398A3
Authority
WO
WIPO (PCT)
Prior art keywords
solvents
pharmaceutical compositions
stabilized
candesartan cilexetil
cilexetil
Prior art date
Application number
PCT/IB2005/000156
Other languages
French (fr)
Other versions
WO2005070398A2 (en
WO2005070398A8 (en
Inventor
Romi Barat Singh
Girish K Karanth
Vishnubhotla Naga Prasad
Original Assignee
Ranbaxy Lab Ltd
Romi Barat Singh
Girish K Karanth
Vishnubhotla Naga Prasad
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd, Romi Barat Singh, Girish K Karanth, Vishnubhotla Naga Prasad filed Critical Ranbaxy Lab Ltd
Publication of WO2005070398A2 publication Critical patent/WO2005070398A2/en
Publication of WO2005070398A3 publication Critical patent/WO2005070398A3/en
Publication of WO2005070398A8 publication Critical patent/WO2005070398A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

The present invention relates to stable pharmaceutical compositions that include candesartan cilexetil and one or more co-solvents.
PCT/IB2005/000156 2004-01-23 2005-01-21 Pharmaceutical compositions of candesartan cilexetil stabilized with co-solvents WO2005070398A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
IN127/DEL/2004 2004-01-23
IN127DE2004 2004-01-23
IN1506/DEL/2004 2004-08-16
IN1506DE2004 2004-08-16
IN2402/DEL/2004 2004-12-01
IN2402DE2004 2004-12-01

Publications (3)

Publication Number Publication Date
WO2005070398A2 WO2005070398A2 (en) 2005-08-04
WO2005070398A3 true WO2005070398A3 (en) 2006-03-30
WO2005070398A8 WO2005070398A8 (en) 2006-05-04

Family

ID=34811697

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/000156 WO2005070398A2 (en) 2004-01-23 2005-01-21 Pharmaceutical compositions of candesartan cilexetil stabilized with co-solvents

Country Status (1)

Country Link
WO (1) WO2005070398A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010502698A (en) * 2006-09-05 2010-01-28 アストラゼネカ アクチボラグ Pharmaceutical composition comprising candesartan cilexetil
WO2008045006A1 (en) * 2006-10-11 2008-04-17 Fako Ilaclari A. S. Formulations of candesartan
WO2008065097A2 (en) * 2006-11-28 2008-06-05 Laboratorios Liconsa, S.A. Stabilized solid pharmaceutical composition of candesartan cilexetil
WO2008068727A2 (en) * 2006-12-06 2008-06-12 Ranbaxy Laboratories Limited Pharmaceutical composition comprising candesartan cilexetil
WO2008084504A2 (en) * 2007-01-12 2008-07-17 Rubicon Research Private Limited Pharmaceutical compositions of angiotensin ii receptor blockers
EP1952806A1 (en) 2007-02-01 2008-08-06 Helm AG Process for the preparation of adsorbates of candesartan
PL384680A1 (en) * 2007-03-28 2008-09-29 Zak & Lstrok Ady Farmaceutyczn Pharmaceutical composition containing cylexyethyl candesarthan and its production method
WO2009017812A2 (en) * 2007-08-01 2009-02-05 Teva Pharmaceutical Industries Ltd. Pharmaceutical composition of candesartan
DE102007052070A1 (en) 2007-10-30 2009-05-07 Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg candesartancilexetil
SI2165702T1 (en) 2008-09-17 2012-05-31 Helm Ag Stable and readily dissolved compositions of candesartan cilexetil prepared with wet granulation
DE102008059206A1 (en) 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmaceutical dosage form containing nifedipine or nisoldipine and an angiotensin II antagonist and / or a diuretic
ES2364011B1 (en) 2009-11-20 2013-01-24 Gp Pharm, S.A. CAPSULES OF PHARMACEUTICAL ACTIVE AND ESTERS OF POLYINSATURATED FATTY ACIDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES.
JP2013067574A (en) * 2011-09-21 2013-04-18 Teva Pharma Japan Inc Stabilized pharmaceutical composition
CN104507459A (en) 2012-05-07 2015-04-08 拜耳制药股份公司 Process for manufacturing a pharmaceutical dosage form comprising nifedipine and candesartan cilexetil
CN117442577B (en) * 2023-12-21 2024-03-15 山东则正医药技术有限公司 Candesartan cilexetil microchip and preparation method and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0546358A2 (en) * 1991-11-20 1993-06-16 Takeda Chemical Industries, Ltd. Pharmaceutical compositions with angiotensin-II-antagonistic activity
WO1997037688A2 (en) * 1996-04-05 1997-10-16 Takeda Chemical Industries, Ltd. Pharmaceutical combination containing a compound having angiotensin ii and antagonistic activity
US6299904B1 (en) * 1997-05-27 2001-10-09 Takeda Chemical Industries, Ltd. Solid pharmaceutical preparation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0546358A2 (en) * 1991-11-20 1993-06-16 Takeda Chemical Industries, Ltd. Pharmaceutical compositions with angiotensin-II-antagonistic activity
WO1997037688A2 (en) * 1996-04-05 1997-10-16 Takeda Chemical Industries, Ltd. Pharmaceutical combination containing a compound having angiotensin ii and antagonistic activity
US6299904B1 (en) * 1997-05-27 2001-10-09 Takeda Chemical Industries, Ltd. Solid pharmaceutical preparation

Also Published As

Publication number Publication date
WO2005070398A2 (en) 2005-08-04
WO2005070398A8 (en) 2006-05-04

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