WO2005067603A2 - Polymorphismes lies a l'autisme et leur usage - Google Patents

Polymorphismes lies a l'autisme et leur usage Download PDF

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Publication number
WO2005067603A2
WO2005067603A2 PCT/US2005/000305 US2005000305W WO2005067603A2 WO 2005067603 A2 WO2005067603 A2 WO 2005067603A2 US 2005000305 W US2005000305 W US 2005000305W WO 2005067603 A2 WO2005067603 A2 WO 2005067603A2
Authority
WO
WIPO (PCT)
Prior art keywords
autism
polymoφhisms
polymoφhic
polymoφhism
gene
Prior art date
Application number
PCT/US2005/000305
Other languages
English (en)
Other versions
WO2005067603A3 (fr
Inventor
Hywel Jones
Malek Faham
Original Assignee
Parallele Bioscience, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parallele Bioscience, Inc. filed Critical Parallele Bioscience, Inc.
Publication of WO2005067603A2 publication Critical patent/WO2005067603A2/fr
Publication of WO2005067603A3 publication Critical patent/WO2005067603A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne un ensemble de sites polymorphes dans des gènes connus ou susceptibles de jouer un rôle dans l'autisme. Cette invention porte sur des acides nucléiques contenant ou avoisinant ces sites polymorphes. Les acides nucléiques peuvent être utilisés comme sondes ou amorces dans des procédés permettant de détecter les nucléotides occupant les sites polymorphes dans un échantillon clinique prélevé sur des patients, et de déterminer si ces patients manifestent une prédisposition à l'autisme ou à des pathologies connexes.
PCT/US2005/000305 2004-01-07 2005-01-05 Polymorphismes lies a l'autisme et leur usage WO2005067603A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53472904P 2004-01-07 2004-01-07
US60/534,729 2004-01-07

Publications (2)

Publication Number Publication Date
WO2005067603A2 true WO2005067603A2 (fr) 2005-07-28
WO2005067603A3 WO2005067603A3 (fr) 2005-12-22

Family

ID=34794310

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/000305 WO2005067603A2 (fr) 2004-01-07 2005-01-05 Polymorphismes lies a l'autisme et leur usage

Country Status (1)

Country Link
WO (1) WO2005067603A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2358907A1 (fr) * 2008-11-12 2011-08-24 University of Utah Research Foundation Marqueurs génétiques associés à l autisme

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6228582B1 (en) * 1997-06-17 2001-05-08 University Of Rochester Genetic polymorphisms which are associated with autism spectrum disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6228582B1 (en) * 1997-06-17 2001-05-08 University Of Rochester Genetic polymorphisms which are associated with autism spectrum disorders

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BOEHRINGER MANNHEIM: 'Nucleic Acid Labelling and Detection' BIOCHEMICALS CATALOG. 1997, page 95 *
DATABASE NCBI [Online] 02 September 2000 NATIONAL CENTER FOR BIOTECHNOLOGY INFORMATION, NATIONAL LIBRARY OF MEDICINE, NIH(BETHESDA, MD,USA), XP002992277 Database accession no. (rs847145) *
INGRAM J.L. ET AL: 'Discovery of Allelic Variants of HOXA1 and HOXB1: Genetic Susceptibility to Autism Spectrum Disorders' TETRAOLOGY vol. 62, no. 6, December 2000, pages 393 - 405, XP002992278 *
ZHONG H. ET AL: 'No association between the EN2 gene and autistic disorder' JOURNAL OF MEDICINAL GENETICS vol. 40, January 2003, pages 1 - 4, XP002992279 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2358907A1 (fr) * 2008-11-12 2011-08-24 University of Utah Research Foundation Marqueurs génétiques associés à l autisme
JP2012508579A (ja) * 2008-11-12 2012-04-12 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション 自閉症関連遺伝子マーカー
EP2358907A4 (fr) * 2008-11-12 2012-06-06 Univ Utah Res Found Marqueurs génétiques associés à l'autisme

Also Published As

Publication number Publication date
WO2005067603A3 (fr) 2005-12-22

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