WO2005062751B1 - Medical material handling systems - Google Patents
Medical material handling systemsInfo
- Publication number
- WO2005062751B1 WO2005062751B1 PCT/US2004/038879 US2004038879W WO2005062751B1 WO 2005062751 B1 WO2005062751 B1 WO 2005062751B1 US 2004038879 W US2004038879 W US 2004038879W WO 2005062751 B1 WO2005062751 B1 WO 2005062751B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- syringe
- material sample
- outlet
- sample
- valve
- Prior art date
Links
- 239000012567 medical material Substances 0.000 title 1
- 239000012530 fluid Substances 0.000 claims abstract 22
- 230000001808 coupling Effects 0.000 claims abstract 16
- 238000010168 coupling process Methods 0.000 claims abstract 14
- 238000005859 coupling reaction Methods 0.000 claims abstract 14
- 210000004369 Blood Anatomy 0.000 claims abstract 10
- 239000008280 blood Substances 0.000 claims abstract 10
- 230000004044 response Effects 0.000 claims abstract 3
- 239000000523 sample Substances 0.000 claims 52
- 239000000463 material Substances 0.000 claims 45
- 210000004027 cells Anatomy 0.000 claims 2
- 230000001276 controlling effect Effects 0.000 claims 2
- 210000001124 Body Fluids Anatomy 0.000 claims 1
- 210000001185 Bone Marrow Anatomy 0.000 claims 1
- 210000003563 Lymphoid Tissue Anatomy 0.000 claims 1
- 210000004080 Milk Anatomy 0.000 claims 1
- 210000000582 Semen Anatomy 0.000 claims 1
- 210000004927 Skin cells Anatomy 0.000 claims 1
- 210000000278 Spinal Cord Anatomy 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 230000000295 complement Effects 0.000 claims 1
- 239000000470 constituent Substances 0.000 claims 1
- 230000000875 corresponding Effects 0.000 claims 1
- 238000006073 displacement reaction Methods 0.000 claims 1
- 239000008267 milk Substances 0.000 claims 1
- 235000013336 milk Nutrition 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 210000000056 organs Anatomy 0.000 claims 1
- 230000000149 penetrating Effects 0.000 claims 1
- 210000001519 tissues Anatomy 0.000 claims 1
Abstract
Disclosed herein is a system for the collection, treatment and delivery of an autologous blood sample, comprising a first syringe having a first body portion. A first sample transfer portion has a first syringe inlet for drawing an untreated blood sample from a patient and a first syringe outlet for dispensing the untreated blood sample. A blood sample treatment chamber having a chamber inlet, the first syringe outlet being operable to establish a dedicated first fluid coupling with the chamber inlet to dispense the untreated blood sample to the blood sample treatment chamber. The blood sample treatment chamber having a chamber outlet for dispensing a treated blood sample following treatment. The second syringe has a second body portion and a second sample transfer portion, the second sample transfer portion having a passage with a first access location which is operable to form a dedicated second fluid coupling with the chamber outlet. The second body portion has a second syringe outlet, the passage having a second access location for fluid communication with the second syringe outlet, releasable lock means for forming a locked third fluid coupling between the second access location and the second syringe outlet. The lock means is operable in response to a release signal to release the third fluid coupling, the second syringe outlet being operable when released from the third fluid coupling to form a fourth fluid coupling with a blood sample delivery unit.
Claims
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AMENDED CLAIMS
[received by the International Bureau on 16 November 2005 (16.11.05) ; Claims 79-120 have been added to former claims 1-78 (8 pages).]
79. A system for the treatment of a material sample, comprising: a first syringe having a first body portion, a first sample transfer portion having a first syringe inlet for receiving an untreated material sample and a first syringe outlet for dispensing the untreated material sample; a material sample treatment chamber having a chamber inlet, the first syringe outlet being operable to establish a dedicated first fluid coupling with the chamber inlet to dispense the untreated material sample to the material sample treatment chamber; the material sample treatment chamber having a chamber outlet for dispensing a treated material sample following treatment; a second syringe having a second body portion and a second sample transfer portion, the second transfer portion having a passage with a first access location which is operable to form a dedicated second fluid coupling with the chamber outlet to receive a treated material sample from said material sample treatment chamber; the second body portion having a second syringe outlet; locking means associated with the second syringe to prevent dispensing of the treated material sample from the second syringe in the absence of a release signal; identification means for identifying a patient, said identification means being associated with the untreated material sample; verification means for verifying a match between the patient and the treated material sample; and release signal generating means for generating the release signal in response to a positive verification by the verification means.
80. A system as defined in claim 79 further including: the passage in the second transfer portion having a second access location for fluid communication with the second syringe outlet; the locking means forming a locked third fluid coupling between the second access location and the second syringe outlet; the locking means being operable in response to the release signal to release the third fluid coupling; and
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the second syringe outlet being operable when released from the third fluid coupling to form a fourth fluid coupling with a material sample delivery unit.
81. A system as defined in claim 79 or claim 80 wherein the identification means and/or the release signal generating means is located on the second syringe body, the locking means further comprising signal receiving means for receiving the release signal.
82. A system as defined in claim 79 or claim 80, or claim 81 wherein the identification means and/or the release signal generating means is located on an external article, the locking means further comprising signal receiving means for receiving the release signal.
83. A system as defined in claim 82 wherein the external article is carried by or worn by the patient.
84. A system as defined in claim 82, or claim 83 wherein the external article contains a removable portion including audit data relating to the patient and/or the treated material sample.
85. A system as defined in any preceding claim wherein the verification means includes comparison means for comparing the patient identity data with the treated material sample identity data, signal receiving means to receive one or more signals associated with the patient identity data and/or the material sample identity data, and memory means for storing the patient identity data and the treated material sample identity data.
86. A system as defined in claim 85 wherein the one or more signals contain the patient identity data and/or the material sample identity data.
. 87. A system as defined in claim 85 or claim 86, wherein the memory means stores time value data to determine at least one time value related to a
-48-
predetermiπed event or between an untreated material sample collection event and a treated material sample delivery event.
88. A system as defined in claim 87 wherein the time value includes at . least one elapsed time value between two predetermined events or between the untreated material sample collection event and the treated material sample delivery event.
89. A system as defined in claim 88 wherein the verification means is operable to prevent release of the locked third fluid coupling when the elapsed time value has exceeded a predetermined elapsed time maximum value.
' 90. A system as defined in any preceding claim, further comprising a material treatment unit to treat the material sample in the material sample treatment chamber, the verification means being operable to prevent treatment of the material sample when the elapsed time value has exceeded a predetermined elapsed time maximum value.
91. A system as defined in any preceding claim wherein the verification means is operable to verify a match between the untreated material sample in the first syringe and the patient.
92. A system as defined in claim 91 wherein the first syringe is assigned a first syringe identity code which is representative of the untreated material sample therein, and the patient is assigned an patient identity code which is representative of the patient, wherein the first syringe and patient identity codes include correlatable data or common data.
93. A system as defined in claim 92 wherein first syringe identity code includes a first time value representative of the time of untreated material sample collection from the patient and/or verification thereof.
94. A system as defined in claim 92 wherein the second syringe is assigned a second syringe identity code, which is representative of the treated material sample therein.
95. A system as defined in claim 94 wherein the second syringe identity code includes a second time value representative of the time of the treated material sample delivery thereto from the material sample treatment chamber and/or verification thereof.
96. A system as defined in any preceding claim wherein the identification means includes a first signal emitting means for emitting a first signal carrying untreated material sample identity data and a first signal receiving means to receive the first signal.
97. A system as defined in claim 96 wherein the first signal emitting means is located on the first syringe.
98. A system as defined in any preceding claim wherein the identification means includes a second signal emitting means for emitting a second signal carrying the treated material sample identity data and a second signal receiving means to receive the second signal.
99. A device as defined in claim 98 wherein the second signal emitting ■ means is located on the second syringe.
100. A system as defined in any preceding claim wherein the first body portion of the first syringe includes an untreated material sample receiving chamber and the first sample transfer portion includes a passage joining the untreated material sample receiving chamber with the first syringe inlet and the first syringe outlet, and first syringe inlet valve means for controlling the flow of material through the first syringe inlet.
101. A system as defined in claim 100 wherein the first syringe inlet valve means including a septum, further comprising a complementary penetrating member located on or intermediate to the external material collection article and in an engaged position therewith.
102. A system as defined in any preceding claim wherein the second sample transfer portion includes a filtered vent outlet in the passage for expelling one or more gas constituents in the treated material sample.
103. A system as defined in any preceding claim wherein one or both of the dedicated first and second couplings are operable releasably to lock the first sample transfer portion of the first syringe and the second sample transfer portion of the second syringe with the material sample treatment chamber in respective open fluid transfer conditions.
104. A system as defined in claim 103 wherein one or both of the dedicated first' and second couplings are operable to establish the locked open fluid transfer condition upon relative rotational displacement between the material sample treatment chamber and the corresponding first and second sample transfer portions.
105. A system as defined in any preceding claim wherein the second syringe outlet includes second syringe outlet valve means for controlling the flow of the material sample there through.
106. A system as defined in claim 105 wherein the second syringe outlet valve means includes a valve element portion and a valve seat portion, and actuating means for actuating the valve element portion relative to the valve seat portion, the actuating means being operable to displace the valve element from the valve seat portion when the second body portion is engaged with the second sample transfer portion.
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107. A system as defined in claim 106 wherein the second sample transfer portion includes a housing to receive the second syringe outlet therein, the housing having a female member in fluid communication with the second access location, the second syringe outlet including a male portion to engage the female portion, the actuating means including an actuating portion adjacent the male portion to be displaced by the female portion on engagement of the female portion with the male portion.
108. A system as defined in claim 107, further comprising an outer sheath portion spaced from the male portion to form an annular female portion-receiving passage therein, the actuating portion including at least one first actuating element positioned in the annular passage.
109. A system as defined in claim 108 wherein the second syringe outlet valve means includes a valve element portion and a valve seat portion, and actuating means for actuating the valve element portion relative to the valve seat portion, the actuating means being operable to engage the valve element with the valve seat portion when the second body portion is separated from the second sample transfer portion, and a second syringe outlet end portion extending outwardly from the second body portion.
110. A system as defined in claim 109 wherein the actuating portion includes at least one second valve actuating element which extends laterally outwardly beyond the second syringe outlet end portion.
111. A system as defined in claim 110 wherein the second outlet end portion has a bevelled distal end and the second valve actuating element has a distal end region which is configured to engage the bevelled distal end of the second outlet end portion.
112. A system as defined in claim 111 wherein the distal end region of the second valve actuating element is angled to nest with the bevelled distal end of the
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second outlet end portion when the valve element portion is engaged with the valve seat portion.
113. A system as defined in claim 112 wherein the second valve actuating element is arranged to travel along an outside surface of the second outlet end portion as the valve portion is displaced relative to the valve seat portion.
114. A system as defined in claim 113, further comprising a collar member located within the bousing, the collar member including a chamber to receive the second outlet end portion to form the third fluid coupling.
115. A system as defined in claim 114 wherein the second valve actuating element includes an abutment flange extending outwardly therefrom, the abutment flange being operable to abut a designated location in the chamber when the second syringe outlet is removed from the chamber.
116. A system as defined as claim 115 wherein the releasable lock means includes a barrier member positioned adjacent the second access location and moveable between a locked position in which the barrier member engages the second outlet end portion, and a release position in which the barrier member is retracted from the second outlet end portion.
117. A system as defined in claim 116 wherein the barrier member is biased to the release position.
118. A system as defined in claim 117, further comprising a brace means for bracing the barrier in the locked position, wherein the brace means is releasable in the presence of a predetermined current.
119. A system as defined in any of the preceding claims wherein said material sample is a biological sample.
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120. A system as defined in claim 119 wherein said material sample is autologous or non-autologous, and includes blood, bone marrow tissue, lymphatic fluids, milk, semen, ova- fluid mixtures, bodily fluids, medical fluids, or samples from organs, spinal cords, body cells, cell tissue, skin cells.
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006541420A JP2007512096A (en) | 2003-11-21 | 2004-11-22 | Medical material handling system |
BRPI0416830-5A BRPI0416830A (en) | 2003-11-21 | 2004-11-22 | medical material handling systems |
CA002546144A CA2546144A1 (en) | 2003-11-21 | 2004-11-22 | Medical material handling systems |
EP04820914A EP1696982A2 (en) | 2003-11-21 | 2004-11-22 | Medical material handling systems |
MXPA06005700A MXPA06005700A (en) | 2003-11-21 | 2004-11-22 | Medical material handling systems. |
AU2004308248A AU2004308248A1 (en) | 2003-11-21 | 2004-11-22 | Medical material handling systems |
IL175798A IL175798A0 (en) | 2003-11-21 | 2006-05-21 | Medical material handling systems |
NO20062908A NO20062908L (en) | 2003-11-21 | 2006-06-21 | Medical equipment handling systems |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52370103P | 2003-11-21 | 2003-11-21 | |
US60/523,701 | 2003-11-21 | ||
US10/991,447 US20050154368A1 (en) | 2003-11-21 | 2004-11-19 | Medical material handling systems |
US10/991,447 | 2004-11-19 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2005062751A2 WO2005062751A2 (en) | 2005-07-14 |
WO2005062751A3 WO2005062751A3 (en) | 2005-11-03 |
WO2005062751B1 true WO2005062751B1 (en) | 2006-02-09 |
Family
ID=34742954
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/038879 WO2005062751A2 (en) | 2003-11-21 | 2004-11-22 | Medical material handling systems |
Country Status (12)
Country | Link |
---|---|
US (1) | US20050154368A1 (en) |
EP (1) | EP1696982A2 (en) |
JP (1) | JP2007512096A (en) |
KR (1) | KR20070013260A (en) |
AU (1) | AU2004308248A1 (en) |
BR (1) | BRPI0416830A (en) |
CA (1) | CA2546144A1 (en) |
IL (1) | IL175798A0 (en) |
MX (1) | MXPA06005700A (en) |
NO (1) | NO20062908L (en) |
RU (1) | RU2006122001A (en) |
WO (1) | WO2005062751A2 (en) |
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2004
- 2004-11-19 US US10/991,447 patent/US20050154368A1/en not_active Abandoned
- 2004-11-22 MX MXPA06005700A patent/MXPA06005700A/en not_active Application Discontinuation
- 2004-11-22 JP JP2006541420A patent/JP2007512096A/en active Pending
- 2004-11-22 BR BRPI0416830-5A patent/BRPI0416830A/en not_active IP Right Cessation
- 2004-11-22 RU RU2006122001/14A patent/RU2006122001A/en not_active Application Discontinuation
- 2004-11-22 WO PCT/US2004/038879 patent/WO2005062751A2/en active Application Filing
- 2004-11-22 AU AU2004308248A patent/AU2004308248A1/en not_active Abandoned
- 2004-11-22 EP EP04820914A patent/EP1696982A2/en not_active Withdrawn
- 2004-11-22 KR KR1020067012267A patent/KR20070013260A/en not_active Application Discontinuation
- 2004-11-22 CA CA002546144A patent/CA2546144A1/en not_active Abandoned
-
2006
- 2006-05-21 IL IL175798A patent/IL175798A0/en unknown
- 2006-06-21 NO NO20062908A patent/NO20062908L/en not_active Application Discontinuation
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