WO2005053835A3 - Artificial receptors including gradients - Google Patents

Artificial receptors including gradients Download PDF

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Publication number
WO2005053835A3
WO2005053835A3 PCT/US2004/040578 US2004040578W WO2005053835A3 WO 2005053835 A3 WO2005053835 A3 WO 2005053835A3 US 2004040578 W US2004040578 W US 2004040578W WO 2005053835 A3 WO2005053835 A3 WO 2005053835A3
Authority
WO
WIPO (PCT)
Prior art keywords
change
building block
artificial receptor
gradients
artificial
Prior art date
Application number
PCT/US2004/040578
Other languages
French (fr)
Other versions
WO2005053835A2 (en
Inventor
Robert E Carlson
Original Assignee
Receptors Llc
Robert E Carlson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Receptors Llc, Robert E Carlson filed Critical Receptors Llc
Priority to JP2006542804A priority Critical patent/JP2007521493A/en
Priority to CA002544614A priority patent/CA2544614A1/en
Priority to EP04817946A priority patent/EP1690092A2/en
Publication of WO2005053835A2 publication Critical patent/WO2005053835A2/en
Publication of WO2005053835A3 publication Critical patent/WO2005053835A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Prostheses (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

The present invention relates to gradients of artificial receptors or building blocks, methods of making the gradients, and methods employing the gradients. The gradient can include one or more building blocks. The gradient can include change in any of a variety of characteristics of the artificial receptor or building block including change in the concentration of an artificial receptor or building block; change in the identity of an artificial receptor or building block; change in the topography of an artificial receptor or building block; change in the mode of binding of an artificial receptor or building block to the support; change in the lawn or lawn modifier; change in charge, volume, lipophilicity, or hydrophilicity of the artificial receptor or building block; or change in a molecular descriptors for the artificial receptor or building block.
PCT/US2004/040578 2003-12-02 2004-12-02 Artificial receptors including gradients WO2005053835A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2006542804A JP2007521493A (en) 2003-12-02 2004-12-02 Artificial receptors including gradients
CA002544614A CA2544614A1 (en) 2003-12-02 2004-12-02 Artificial receptors including gradients
EP04817946A EP1690092A2 (en) 2003-12-02 2004-12-02 Artificial receptors including gradients

Applications Claiming Priority (18)

Application Number Priority Date Filing Date Title
US52719003P 2003-12-02 2003-12-02
US60/527,190 2003-12-02
US60745804P 2004-09-03 2004-09-03
US60745704P 2004-09-03 2004-09-03
US60743804P 2004-09-03 2004-09-03
US60/607,457 2004-09-03
US60/607,438 2004-09-03
US60/607,458 2004-09-03
US60865404P 2004-09-10 2004-09-10
US60855704P 2004-09-10 2004-09-10
US60/608,654 2004-09-10
US60/608,557 2004-09-10
US60916004P 2004-09-11 2004-09-11
US60/609,160 2004-09-11
US61266604P 2004-09-23 2004-09-23
US60/612,666 2004-09-23
US62208604P 2004-10-25 2004-10-25
US60/622,086 2004-10-25

Publications (2)

Publication Number Publication Date
WO2005053835A2 WO2005053835A2 (en) 2005-06-16
WO2005053835A3 true WO2005053835A3 (en) 2005-11-03

Family

ID=34658349

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/040578 WO2005053835A2 (en) 2003-12-02 2004-12-02 Artificial receptors including gradients

Country Status (4)

Country Link
EP (1) EP1690092A2 (en)
JP (1) JP2007521493A (en)
CA (1) CA2544614A1 (en)
WO (1) WO2005053835A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114220480B (en) * 2022-02-17 2022-05-10 武汉宏韧生物医药股份有限公司 Method and system for analyzing pharmaceutical ingredients

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1192448E (en) * 1999-07-05 2007-01-31 Novartis Ag Process of using a sensor platform
US6656432B1 (en) * 1999-10-22 2003-12-02 Ngk Insulators, Ltd. Micropipette and dividedly injectable apparatus
JP2003149242A (en) * 2001-11-09 2003-05-21 Gifu Univ Method of detecting antibody and antigen micro-array
GB0127989D0 (en) * 2001-11-22 2002-01-16 Glaxo Group Ltd Medicament dispensing system

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DELONG S A ET AL: "Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 26, no. 16, June 2005 (2005-06-01), pages 3227 - 3234, XP004684987, ISSN: 0142-9612 *
DERTINGER STEPHAN K W ET AL: "Gradients of substrate-bound laminin orient axonal specification of neurons.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1 OCT 2002, vol. 99, no. 20, 1 October 2002 (2002-10-01), pages 12542 - 12547, XP002342473, ISSN: 0027-8424 *
HYPOLITE C L ET AL: "Formation of microscale gradients of protein using heterobifunctional photolinkers.", BIOCONJUGATE CHEMISTRY. 1997 SEP-OCT, vol. 8, no. 5, September 1997 (1997-09-01), pages 658 - 663, XP002342474, ISSN: 1043-1802 *
KRÄMER STEPHAN ET AL: "Preparation of protein gradients through the controlled deposition of protein-nanoparticle conjugates onto functionalized surfaces.", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 5 MAY 2004, vol. 126, no. 17, 5 May 2004 (2004-05-05), pages 5388 - 5395, XP002342491, ISSN: 0002-7863 *

Also Published As

Publication number Publication date
JP2007521493A (en) 2007-08-02
EP1690092A2 (en) 2006-08-16
CA2544614A1 (en) 2005-06-16
WO2005053835A2 (en) 2005-06-16

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